Gene Information

Name : smpB (PG0502)
Accession : NP_904797.1
Strain : Porphyromonas gingivalis W83
Genome accession: NC_002950
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 541599 - 542060 bp
Length : 462 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGAAAGAGAAAATACAGAAGAATATCCTCATAAAGAACAAACGTGCCACTTTCGATTACGAGATTTTGGACGTTTACAC
GGCGGGCATTGTATTGGTCGGTACCGAGATCAAATCGCTCCGACTGGGCAAAGGCGGTTTGGTTGATACCTATTGCTACT
TCCATCGGGGAGAGCTGTGGGTGAAGAATATGTACATAGCCGAATACTTCTATGGCACCTATAACAACCATGTGGCTCGC
CGCGACCGTAAACTCCTCCTTAATCGCAAAGAGCTACGCAAGCTTGAGGAGGCATCCAAGAGCATGGGTACCACGATAGT
GCCGCTCAAGCTCTTTATCAATGAAAGGGGATTGGCCAAGCTGCAAATCGGATTGGCACGAGGGAAAAAACAATATGACA
AACGTGCATCCATCAAAGAGCGAGATGATCGCCGAGAGATGGATCGTGCATTGAAACGCTAA

Protein sequence :
MKEKIQKNILIKNKRATFDYEILDVYTAGIVLVGTEIKSLRLGKGGLVDTYCYFHRGELWVKNMYIAEYFYGTYNNHVAR
RDRKLLLNRKELRKLEEASKSMGTTIVPLKLFINERGLAKLQIGLARGKKQYDKRASIKERDDRREMDRALKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-17 47
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 2e-21 47