Gene Information

Name : serS (PG0316)
Accession : NP_904632.1
Strain : Porphyromonas gingivalis W83
Genome accession: NC_002950
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 348577 - 349848 bp
Length : 1272 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTGACACTCAAGCAAATCATAGAAAACAAGGAAGAAGTGATCCGTCGCTTGGCGGTGAAGCACTTCGATGCAGCTGC
TATTCTCGACGAAGTCATCTCTCTCGACAGACAGCGACGCGAAACTCAACAGAGTCTGGATGCTCGCTTGGCGGAGCAAA
ACGCCATTGCCAAGGAGATCGGAGCTTTGATGAAAGCCGGCAAGAAAGACGAGGCAGAGGCCATCCGTGCGAAAGTAGCC
GATATGAAAGCCGGGAGCCACCATCTGGAAGAGCGGAAAGCTGATCTGGAGAATGCTATACGCCAACAGCTTCTGCTTAT
CCCGAATCTGCCGCATGAGTCTGTCCCTGCAGGCAAGACCGCAGAGGAGAATGTCTGTGTGAAGACAGGCGGCACAGTGC
CGGAGCTTGGAACGCACAAGCTCCCACATTGGGATCTGGCCAAGAAATACGATCTGATCGACTTCGAACTCGGCGTCAAG
ATAACCGGAGCAGGCTTCCCTGTCTATAAGGGCAAAGGAGCACGCCTGCAGCGAGCTTTGGTCAACTTCTTCTTGGATGA
AGCCCGCAACGCCGGCTTCACGGAGATAGAGCCGCCCTATGTAGTCAATGAGGATTCCGGCTACGGTACGGGACAGCTCC
CTGACAAGGAAGGGCAGATGTACCATGTCACGGCGGACAACCTGTATCTGATCCCCACGGCAGAGGTGCCGGTGACCAAT
ATCTTCCGCGATGTCATTCTCTCCGAGGACGAATTGCCCATTCTCCTGACCGCTTACTCGGCTTGCTTCCGACGCGAAGC
CGGTTCGTACGGCAAGGATGTTCGCGGTCTGAACCGCCTCCATCAGTTCAACAAGGTGGAGATCGTCTGCATCGACAAGC
CCGAACACTCCTACGAACAGCTCGATCAGATGGTCGGCTATGTCCAAGGCCTTGTAGATAAGTTGGGACTTCCGTGGCGT
ATCCTTCGCCTCTGCGGCGGAGATATCAGCTTCACTTCGGCATTGACTTACGATTTCGAAGTCTATTCGGCTGCCCAAGA
GCGGTGGTTGGAGGTTAGCTCGGTGTCCAATTTCGAGAGCTTCCAAGCCAATCGTCTGAAGTGCCGTTATCGCAATGCGG
ATAAGAAAGTGGAGCTTTGCCACACGCTCAACGGTAGTGCCTTGGCCTTGCCGCGTATCGTGGCTGCTCTGCTGGAAAAC
AATCAGACAGCCGATGGCATCCGCATCCCCGACTGTCTGGTGCCTTATACAGGCTTCTCGATGATCGATTGA

Protein sequence :
MLTLKQIIENKEEVIRRLAVKHFDAAAILDEVISLDRQRRETQQSLDARLAEQNAIAKEIGALMKAGKKDEAEAIRAKVA
DMKAGSHHLEERKADLENAIRQQLLLIPNLPHESVPAGKTAEENVCVKTGGTVPELGTHKLPHWDLAKKYDLIDFELGVK
ITGAGFPVYKGKGARLQRALVNFFLDEARNAGFTEIEPPYVVNEDSGYGTGQLPDKEGQMYHVTADNLYLIPTAEVPVTN
IFRDVILSEDELPILLTAYSACFRREAGSYGKDVRGLNRLHQFNKVEIVCIDKPEHSYEQLDQMVGYVQGLVDKLGLPWR
ILRLCGGDISFTSALTYDFEVYSAAQERWLEVSSVSNFESFQANRLKCRYRNADKKVELCHTLNGSALALPRIVAALLEN
NQTADGIRIPDCLVPYTGFSMID

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-73 45