Gene Information

Name : thiC (PG2110)
Accession : NP_906170.1
Strain : Porphyromonas gingivalis W83
Genome accession: NC_002950
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2219539 - 2221302 bp
Length : 1764 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGAAAGAATTCAAAGTGACTACCGGTCCTCTGCCCGGCAGTGAGAAAATCTATGTCGAAGGAGAGCGTTTCCCCTTCTT
GCGCGTACCGATGCGGCGCATCCGAATGTCCGACACCATATTGGAGAACGGCGAACGTGAGAAAAACGAAGATGTAGTCG
TATACGATACCAGTGGCCCCTATACCGATACCTCCTATGAGGTGAATCTGCACCGAGGCGTACCGAAGATACGCGAGCAG
TGGATAGAGGATCGGGGCGATACGGTGCGGCTCGAAGGGCTCAGCTCCGAATACGGACGGATAAGGCAGTCGGACGCTTC
GCTCGAAAAGCTGCGTTACGAGCATGTGTGCACGCGTCCCCGTGCCGCCAAGGACGGCTGTGCCACGCAGCTCTACTACG
CCCGTCAGGGGATCGTGACGCCGGAGATGGAGTTCGTGGCCATCCGCGAAAATCAGTTGATCGATCAGGTCAGGACGCGC
TATCGCGCTGAGGAGGGTGAGCCGCTCGGAGCTGTTATTCCGCGCAAGATCACGCCCGAATTTGTACGCGACGAGATTGC
CGCCGGACGGGCTATCCTTCCGGCCAATATCAATCATCCGGAAAGTGAGCCGATGATCATCGGGCGCAATTTCCTCGTCA
AGATCAATGCGAACATAGGCAATTCGCCCATCAGCAGTACCATCGAGGAAGAGGTGGAAAAGGCCGTCTGGGCCATACGC
TGGGGTGCCGATACGGTCATGGATCTCTCCACGGGGGATCATATCCATGAGACGCGCGAGTGGATCATCCGCAATTCGCC
CGTGCCCATCGGCACTGTGCCCCTCTACCAGACGCTGGAGAAGGTGCAGGGCGATGTGACGAAGCTCAACTGGGAGATAT
TCCGCGATACGCTCATCGAGCAGGCCGAGCAGGGTGTGGACTACTTCACCATCCACGCCGGTCTGCGTTGGCACCACGTG
CCTCTGACCTTGCGCCGCCTCACGGGGATCGTCTCCCGCGGTGGTTCCATCATCGCCAACTGGTGCACCACCCACAAGCG
CGAAAGTTTCATCTACGAGCATTTCGAAGAGATCTGCCAAATCCTCGCACGCTACGACGTAGCCATATCTCTCGGCGATG
GCTTGCGCCCGGGCTGCATCCACGACGCCAACGATGCTGCGCAGATAGCTGAGCTGAAGACGCTGGGCGAACTTACCGAG
ATCGCTTGGAAGTATAACGTGCAAACCATTATCGAAGGACCGGGACACGTGCCCATGCACAAGATCCGCGAGAATATGGA
GATTCAACTCGAAGCCTGCCATGGCGCACCCTTCTACACTCTCGGCCCGTTGGTCAGCGACGTGGCGTCCGGCTACGACC
ATATCACATCGGCTATCGGCGCGGCACAGATCGGATGGTTCGGCACAGCCATGCTCTGCTATGTGACGCAAAAGGAGCAT
TTGGGTCTGCCCAACCGCGAAGATGTACGTGAAGGTGTAGTAACCTATAGACTGGCTGCTCATGCCGCCGACTTGGCCAA
AGGACACCCCACGGCGTACTGGCGCGACTATATGATGAGCAAGGCGCGGTTCGAATTCCGCTGGAAGGATCAGTTCCATC
TCTCGCTTGATCCAGAGAAAGCGATCCAATTCCACGATGCCACGCTGCCGGACGAAGGCCACAAAGAGGCGCATTTCTGC
TCCATGTGCGGCGAACACTTCTGCTCCATGCGTGCCAATAAGAACTTCCGCAAGTTGCTAAACGAAGAGGCAGTCTCCAA
ATGA

Protein sequence :
MKEFKVTTGPLPGSEKIYVEGERFPFLRVPMRRIRMSDTILENGEREKNEDVVVYDTSGPYTDTSYEVNLHRGVPKIREQ
WIEDRGDTVRLEGLSSEYGRIRQSDASLEKLRYEHVCTRPRAAKDGCATQLYYARQGIVTPEMEFVAIRENQLIDQVRTR
YRAEEGEPLGAVIPRKITPEFVRDEIAAGRAILPANINHPESEPMIIGRNFLVKINANIGNSPISSTIEEEVEKAVWAIR
WGADTVMDLSTGDHIHETREWIIRNSPVPIGTVPLYQTLEKVQGDVTKLNWEIFRDTLIEQAEQGVDYFTIHAGLRWHHV
PLTLRRLTGIVSRGGSIIANWCTTHKRESFIYEHFEEICQILARYDVAISLGDGLRPGCIHDANDAAQIAELKTLGELTE
IAWKYNVQTIIEGPGHVPMHKIRENMEIQLEACHGAPFYTLGPLVSDVASGYDHITSAIGAAQIGWFGTAMLCYVTQKEH
LGLPNREDVREGVVTYRLAAHAADLAKGHPTAYWRDYMMSKARFEFRWKDQFHLSLDPEKAIQFHDATLPDEGHKEAHFC
SMCGEHFCSMRANKNFRKLLNEEAVSK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 65
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 65
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 1e-180 63