Gene Information

Name : kdsB (PG1815)
Accession : NP_905914.1
Strain : Porphyromonas gingivalis W83
Genome accession: NC_002950
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 1910759 - 1911523 bp
Length : 765 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAATACAGAGGTAATAGCCATCATTCCGGCTCGATTTGCTTCCAGCCGATTCCCGGGCAAGCCACTGGCCGATATGCT
TGGCAAGTCTATGATCCAACGGGTACATGAGCGAATAGTCGGTGTCGTCCCCCGGGCCGTCGTAGCCACCGATGACGAAC
GTATCCGTCAGGCCGTGGAGGACTTCGGAGGAGAGGTGGTGATGACGTCCCCAGAGTGCAGTAGTGGTACAGAACGCTGT
CGGGAGGCATTCGACAAAGTAGGTCGGGGAGAAAAGATCGTCCTGAATCTGCAAGGCGATGAACCTTTTATCCAAAAGGA
ACAGATCGATCTGCTGATTTCGGCCTTCGACAAACCAGAAACCGATATAGCTACGTTAGCAGAAGTTTTCTCGTCTGACG
TAAGCTTCGAGCGTTTGAACAATCCAAACAGCCCGAAGATCGTATTGGATCATGGAGGCTATGCCCTTTATTTCAGCCGC
TCCGTTATCCCATATCTCAGGGGGGTACAGCCTGACTCTTGGTGCCGTCGGCATACTTACTACAAGCATATCGGGATCTA
TGCCTTTCGCCCGACCGTCCTCCGCAAGATAACCTCACTGCCACAAAGTACGGCAGAGCAAGCCGAAAGTCTCGAACAGC
TTCGCTGGCTGGAATACGGCTATCGGATTCGAGTGCTGCAAACACAGCAGAGTACGATAGGAATCGATACGCCGGAGGAT
ATGGAGAAGGCCATAGCCTATCTCCGTTCGCAGGGAATGGAATGA

Protein sequence : 
MNTEVIAIIPARFASSRFPGKPLADMLGKSMIQRVHERIVGVVPRAVVATDDERIRQAVEDFGGEVVMTSPECSSGTERC
REAFDKVGRGEKIVLNLQGDEPFIQKEQIDLLISAFDKPETDIATLAEVFSSDVSFERLNNPNSPKIVLDHGGYALYFSR
SVIPYLRGVQPDSWCRRHTYYKHIGIYAFRPTVLRKITSLPQSTAEQAESLEQLRWLEYGYRIRVLQTQQSTIGIDTPED
MEKAIAYLRSQGME

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 1e-38 44
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 2e-38 44
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 1e-38 44