Gene Information

Name : leuS (PP_4794)
Accession : NP_746899.1
Strain : Pseudomonas putida KT2440
Genome accession: NC_002947
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 5456267 - 5458873 bp
Length : 2607 bp
Strand : +
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGCACGAACAATACACGCCCCGTGATATCGAAGCCGCCGCCCAGAAGTTCTGGGACGAGCAACAATCGTTCGCTGTTAC
CGAACAGCCAGGCAAAGACACCTACTATTGCCTATCGATGTTCCCGTACCCGAGCGGCAAGCTACACATGGGCCACGTGC
GCAACTACACCATCGGTGACGTGATTGCCCGCTACCAGCGCATGCTGGGCAAGAACGTCCTGCAGCCGATGGGCTGGGAC
GCTTTCGGCATGCCCGCGGAAAACGCGGCGATGAAAAACAACGTCGCCCCGGCCAAGTGGACGTACGAAAACATCGACTA
CATGAAGACCCAGCTCAAGAGCCTGGGCCTGGCCATCGACTGGGCACGTGAAGTCACCACCTGCAAACCCGACTATTACC
GTTGGGAGCAGTGGCTGTTCACCCGCCTGTTCGAAAAAGGCATCATCTACCGCAAGAACGGTACCGTGAACTGGGACCCG
GCGGACCAGACCGTACTGGCCAACGAACAAGTCATCGACGGCCGTGGCTGGCGTTCGGGCGCGCTGATCGAGAAGCGCGA
AATCCCGATGTACTACTTCCGCATCACCGATTACGCCGACGAGCTGCTGGAGAGCCTTGACGAGCTGCCGGGCTGGCCTG
AGCAGGTCAAGACCATGCAGCGCAACTGGATCGGCAAATCGCGCGGCATGGAAGTCCAGTTCCCGTACGACAAGGCCAGC
ATCGGCCACGAAGGCACCCTCAAGGTCTTCACCACCCGTCCGGACACGCTGATGGGCGCCACCTATGTCGCCGTCGCCGC
CGAGCACCCGCTGGCCACCCAGGCTGCGCAGGGCAACCCGGCGCTGCAGGCGTTCATCGATGAGTGCAAGAGCGGCAGCG
TTGCCGAAGCCGACATGGCCACCCAGGAGAAGAAAGGCATGGCCACTTCCCTGCTGGTCGAGCACCCGCTCACCGGCGAG
AAGCTGCCAGTATGGGTCGCCAACTACGTGCTGATGCACTACGGCGATGGCGCGGTAATGGCCGTGCCGGCCCACGACGA
GCGCGACTTCGAGTTCGCCCACAAGTACAACTTGCCGGTCAAGGCCGTGGTGCGCACCAGCGCTGGCGATGAAGTCGGCA
GCGAGTGGCAGGCCGCCTATGGTGAGCACGGCCAGCTGATCAACTCCGCAGAATTCGACGGCCTGGACTTTGCTGGCGCC
TTCGACGCCATCGAAGCGGCCCTGATCCGCAAGGAACTGGGCAAATCGCGTACACAGTTCCGCCTGCGCGACTGGGGTAT
CAGCCGCCAGCGCTACTGGGGCTGCCCGATCCCGATCATCCACTGCCCGTCCTGCGGCGACGTCCCGGTGCCGGAAGACC
AGCTGCCGGTCACCCTGCCGGAGAACGTGGTGCCGGACGGCGCCGGTTCGCCACTGGCACGCATGCCTGAATTCTACGAA
TGCAGCTGCCCGAAATGCGGTGCTGCGGCCAAGCGCGAAACCGACACCATGGACACCTTCGTCGAGTCGTCCTGGTACTT
CGCCCGCTACGCCTCGCCAAACTACGACAAAGGCCTGGTCGACCCCAAAGCCGCCAACCACTGGCTGCCGGTAGATCAGT
ACATCGGCGGTATCGAACACGCGATCCTGCACCTGCTGTACGCGCGCTTCTTCCACAAGCTGATGCGTGACGAAGGCCTG
GTCACCTCGAACGAGCCGTTCAAGAACCTGCTGACCCAGGGCATGGTGGTCGCCGAAACCTACTACCGCGTTGCCAGCAA
CGGCGGCAAGGACTGGTTCAACCCGGCCGATGTCGAAATCGAGCGTGATGCCAAAGCCAAGATCATTGGCGCCCGCCTGA
AGACCGACGGCTTGCCGGTGGAAATCGGTGGCACCGAGAAAATGTCGAAGTCGAAAAACAACGGCGTCGACCCGCAGTCC
ATGATCGAAGCCTACGGCGCCGACACCTGCCGCCTGTTCATGATGTTCGCCTCGCCGCCCGACATGAGCCTGGAATGGTC
CGACTCCGGCGTCGAAGGTGCCAGCCGCTTCCTGCGCCGTGTCTGGCGTCTGGCTCAGGCTCACGTCAGCCAGGGCCTGC
CAGGCAAGCTGGATGTTGCCGCCCTGGACGACGCGCAAAAGGTCATCCGCCGCGCCATTCACGCTGCCATCAAGCAGGCC
AGCACCGACGTGGGCCAGTTCCACAAGTTCAATACCGCCATCGCCCAGGTGATGACCGTGATGAACGTGCTGGAAAAGGC
CCCGCAAGCCACCGAACAGGACCGCGCCCTGCTGCAGGAAGGCCTGGAAGCCGTCACCCTGCTGCTGGCGCCGATCACTC
CGCACATCTCTCACGCGCTGTGGCAGCACCTGGGCCACGCAGGCTCGGTGATCGATGCCGCCTGGCCAAGCGTCGACGAA
CAGGCGCTGGTGCAGGACTCCATTACCTTGGTGGTTCAGGTCAACGGTAAACTGCGCGGCCAGGTCGAGATGCCTGCCGC
TGCCAGCCGCGAAGAAGTCGAAGCCGCTGCCCGCAGCAACGAGAATGTCCTGCGCTTCATCGATGGCCTGACCATCCGCA
AGGTCATCGTGGTACCGGGCAAGCTGGTCAACATCGTCGCCAACTGA

Protein sequence :
MHEQYTPRDIEAAAQKFWDEQQSFAVTEQPGKDTYYCLSMFPYPSGKLHMGHVRNYTIGDVIARYQRMLGKNVLQPMGWD
AFGMPAENAAMKNNVAPAKWTYENIDYMKTQLKSLGLAIDWAREVTTCKPDYYRWEQWLFTRLFEKGIIYRKNGTVNWDP
ADQTVLANEQVIDGRGWRSGALIEKREIPMYYFRITDYADELLESLDELPGWPEQVKTMQRNWIGKSRGMEVQFPYDKAS
IGHEGTLKVFTTRPDTLMGATYVAVAAEHPLATQAAQGNPALQAFIDECKSGSVAEADMATQEKKGMATSLLVEHPLTGE
KLPVWVANYVLMHYGDGAVMAVPAHDERDFEFAHKYNLPVKAVVRTSAGDEVGSEWQAAYGEHGQLINSAEFDGLDFAGA
FDAIEAALIRKELGKSRTQFRLRDWGISRQRYWGCPIPIIHCPSCGDVPVPEDQLPVTLPENVVPDGAGSPLARMPEFYE
CSCPKCGAAAKRETDTMDTFVESSWYFARYASPNYDKGLVDPKAANHWLPVDQYIGGIEHAILHLLYARFFHKLMRDEGL
VTSNEPFKNLLTQGMVVAETYYRVASNGGKDWFNPADVEIERDAKAKIIGARLKTDGLPVEIGGTEKMSKSKNNGVDPQS
MIEAYGADTCRLFMMFASPPDMSLEWSDSGVEGASRFLRRVWRLAQAHVSQGLPGKLDVAALDDAQKVIRRAIHAAIKQA
STDVGQFHKFNTAIAQVMTVMNVLEKAPQATEQDRALLQEGLEAVTLLLAPITPHISHALWQHLGHAGSVIDAAWPSVDE
QALVQDSITLVVQVNGKLRGQVEMPAAASREEVEAAARSNENVLRFIDGLTIRKVIVVPGKLVNIVAN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 7e-148 41