Gene Information

Name : topB (PP_4019)
Accession : NP_746149.1
Strain : Pseudomonas putida KT2440
Genome accession: NC_002947
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 4530160 - 4532121 bp
Length : 1962 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGCGCCTGTTTCTCTGCGAAAAACCCTCCCAGGCAAAAGACATCGCCAAAGTGCTCGGCGCCAACCGCAAAGGCGACGG
CTGCTGGCAAGGCACCGACATCTGCGTAACCTGGTGCATCGGCCACCTGCTGGAAACCGCCCCGCCCGACAGCTACGACG
AACGTTACAAGCGCTGGAACCTGGCCGACCTGCCGATCATTCCAGACAAGTGGAAGATGCTGGTAAAGCCCAAGACTGCC
AGCCAGTTCAAGGCGGTCAAGCGCCTGCTCGGTGAAGCGCGGGAGCTGGTGATTGCCACCGACGCCGACCGCGAAGGCGA
AATGATTGCCCGCGAGCTGGTCGAGCATTGCCGCTACCGGGGCCCGGTGCAGCGCCTGTGGCTGTCGGCACTGGACGACG
CCTCCATCCGCAAGGCCCTGGCACGCCTGCTGCCAGGCCACGAGACGTTCAACCTGTACCACTCGGCACTGGGCCGATCG
CGCGCCGACTGGCTGATCGGCATGAACATGAGCCGGCTGTTCACCCTGCTGGGCCGCCAATCCGGCTACCAGGGTGTGCT
GCCGGTAGGCCGCGTACAAACGCCTACCTTGCGCCTGGTGGTCGACCGCGACCGCAGCATCGCCAACTTCGTGCCGGTGC
CGTTCTGGGCCATCGACGTACAGCTGGAACACGCCGGCCAACGCTTCAATGCCCAATGGCGCGCCCCCGAAGACGCCTGC
GACGACCAAGGCCGCTGCCTGAAGCAAAGCCTGGCTCAGCAGGCCGCGGCCGACATCGGCCATGCCGGCACTGCCCGAGC
GGTAAAGGTGGCGACCGAGCGTGTGCGCGAAGCAGCACCGCTACCCTTCGACCTTGGCACCCTGCAGGAGCTGTGCTCGA
AAAAGTTCGGCCTCGGCGCCCAGGAAACCCTCGACATTGCCCAGGCACTGTACGAAACACACAAGCTAATCACCTACCCG
CGCAGCGATTGCGGCTATTTGCCACAAAGCCAGCACGCCGAGGCACCCGCCATCCTTGCCGCCCTGCAACGGGCCGATGC
CAGCCTTGCGCCGCTGCAGCCCTACCTGGAGCCGCAACGCCGCTCGCGGGCGTGGAACGACGCCAAGGTCAGCGCTCACC
ATGGCATCATCCCCACCGCCGCCGCCAGCGACCCCTCGCGCCTGCCGGCCAAGCACAAGGCCGTGTACACCCTGATCCGC
GCCCGCTATCTGGCGCAGTTCCTGCCCAACCATGAGTACGACCGCACCCAGGCGGACTTCGACTGCGCCGGTCATGCGCT
GCGTGCTGTGGGCAAACAGATCGTCGAGCCGGGCTGGCGCCGCGCCTTGCCCGAAGCGCTGACCCCGGCCAAAGGCCGCG
AGGCACCACCGGCCCAGGTGTTGCCAGCGCTGCGCGAAGGCCAGGACTGCAACGTACACGGCCTGCAACTGAAAGACCTG
TGGACCCAGCCGCCCAAGCCGTTTACCGAAGGCGACCTGATCAAGGCGATGAAAAACGTGGCCAAGCTGGTGGATGACCC
TCGGCTGAAGCAGAAGCTCAAGGAAACCACCGGCATTGGCACCGAAGCCACCCGCGCCAGCATCATCCAGGGCCTGCTCG
ACCGCGGTTACCTGGTGAAGAACGGCAAGGCGTTGTCGGCCACACCTGCGGCCTTCAGCCTGATCGACGCCGTTCCCCGC
GCGATTGCCGACCCCGGTACCACGGCGATCTGGGAGCAGGCGCTGGACATGGTGCAAAGCGGCGAGATGCCCCTGGAAGA
GTTCGTCGCCCGGCAGTCAGCGTGGATGGGCAAGCTGGTCGAGCGTTGCAGCGGCATGCGCATGACCATCAGCGGGCCAG
CGGCCGGGGCGGCCCCGCCCTGGAAAAAGAAACGTCGCGGTGGCGGGAAGAGCAAAGCGACTGGAAGCAAGGCGACCCCA
AGCAAGCCACGGCAGGCGCGAAAAAAGCGAGCCCCCCTGTAG

Protein sequence :
MRLFLCEKPSQAKDIAKVLGANRKGDGCWQGTDICVTWCIGHLLETAPPDSYDERYKRWNLADLPIIPDKWKMLVKPKTA
SQFKAVKRLLGEARELVIATDADREGEMIARELVEHCRYRGPVQRLWLSALDDASIRKALARLLPGHETFNLYHSALGRS
RADWLIGMNMSRLFTLLGRQSGYQGVLPVGRVQTPTLRLVVDRDRSIANFVPVPFWAIDVQLEHAGQRFNAQWRAPEDAC
DDQGRCLKQSLAQQAAADIGHAGTARAVKVATERVREAAPLPFDLGTLQELCSKKFGLGAQETLDIAQALYETHKLITYP
RSDCGYLPQSQHAEAPAILAALQRADASLAPLQPYLEPQRRSRAWNDAKVSAHHGIIPTAAASDPSRLPAKHKAVYTLIR
ARYLAQFLPNHEYDRTQADFDCAGHALRAVGKQIVEPGWRRALPEALTPAKGREAPPAQVLPALREGQDCNVHGLQLKDL
WTQPPKPFTEGDLIKAMKNVAKLVDDPRLKQKLKETTGIGTEATRASIIQGLLDRGYLVKNGKALSATPAAFSLIDAVPR
AIADPGTTAIWEQALDMVQSGEMPLEEFVARQSAWMGKLVERCSGMRMTISGPAAGAAPPWKKKRRGGGKSKATGSKATP
SKPRQARKKRAPL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB AAN62317.1 putative DNA topoisomerase III Not tested PAGI-3(SG) Protein 0.0 65
topB AAN62194.1 putative DNA topoisomerase III Not tested PAGI-2(C) Protein 0.0 63
pph56 CAI36097.1 Topoisomerase IA Not tested PPHGI-1 Protein 0.0 63
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 3e-151 51
topB NP_458624.1 topoisomerase B Not tested SPI-7 Protein 8e-152 50
topB NP_807836.1 DNA topoisomerase III Not tested SPI-7 Protein 8e-152 50
topB AAF14809.1 topoisomerase B Not tested SPI-7 Protein 6e-152 50
PMI2630 YP_002152332.1 DNA topoisomerase III Not tested Not named Protein 2e-150 49
topB AAW83109.1 TopB Not tested GGI Protein 1e-118 43