Gene Information

Name : kdsB (PP_1902)
Accession : NP_744057.1
Strain : Pseudomonas putida KT2440
Genome accession: NC_002947
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 2144880 - 2145644 bp
Length : 765 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGCCTGGAATTTACGGTAGTAATCCCCGCCCGGCTGCGCTCCACCCGCCTGCCAGGCAAACCGCTGCTGCTGATTGC
CGGCAAGCCGATGGTGCAACATGTGTGGGAGCAGGCCCGCAAGAGCGGTGCCAGCCGTGTGGTCATCGCCACCGACGACA
CCAGCATCCTCGAAGCCTGCCAGGCCTTCGGTGCTGAAGTGATGATGACCCGTGCCGATCATGAATCGGGCACTGACCGC
CTGGCCGAAGTGGCCGCGTACCTAGGGTTGCCGGCTGACGCCATTGTGGTCAACGTGCAGGGCGACGAGCCGCTGATCCC
GCCGGTGATCATCGACCAGGTGGCGGCCAACCTGGCTGCGCATCCGGAAGCCGGTATCGCCACCCTGGCCGAGCCGATCC
ATGAGCCGGAAACCGTGTTCAACCCGAACGCGGTCAAGGTGGTGAGTGACAAGAACGGCCTGGCCCTGACGTTCAGCCGA
GCGCCGCTGCCCTGGGCCCGCGATACCTTTGCCAAGGCCCGCGACGTGCTGCCGGAAGGGGTGCCCTATCGCCGTCATAT
TGGCATGTACGCCTACCGTGTCGGCTTCCTGCACGACTTCGTCAGCTGGGGCCCATGCTGGCTCGAGCAGGCTGAAGCGC
TGGAGCAGCTGCGTGCCCTGTGGCACGGCGTACGCATTCACATCGAGGACGCCATCGAGGCGCCTGCCGTGGGTGTCGAC
ACCCCAGAGGATCTGGAGCGCGTACGGCGCTTGCTGGAGGCCTGA

Protein sequence : 
MSLEFTVVIPARLRSTRLPGKPLLLIAGKPMVQHVWEQARKSGASRVVIATDDTSILEACQAFGAEVMMTRADHESGTDR
LAEVAAYLGLPADAIVVNVQGDEPLIPPVIIDQVAANLAAHPEAGIATLAEPIHEPETVFNPNAVKVVSDKNGLALTFSR
APLPWARDTFAKARDVLPEGVPYRRHIGMYAYRVGFLHDFVSWGPCWLEQAEALEQLRALWHGVRIHIEDAIEAPAVGVD
TPEDLERVRRLLEA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 2e-38 45
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-38 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-38 45