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Name : ldhA (PP_1649) Accession : NP_743806.1 Strain : Pseudomonas putida KT2440 Genome accession: NC_002947 Putative virulence/resistance : Resistance Product : D-lactate dehydrogenase Function : - COG functional category : C : Energy production and conversion COG ID : COG1052 EC number : - Position : 1840970 - 1841998 bp Length : 1029 bp Strand : - Note : Catalyzes the reduction of sulfopyruvate to (R)-sulfolactate much more efficiently than the reverse reaction. Also catalyzes the reduction of oxaloacetate, alpha-ketoglutarate, and to a much lower extent, KHTCA, but not pyruvate. Involved in the biosynthe DNA sequence : GTGACCCACCCAAGACATGCATTGCAAAGGAGTTCGACCATGCGCGCCCTGTTGTTCAGCAGCCAGCACTACGATCAGGA AAGCTTCACCAAGGCTGCCGGCGGCACCGCCCTGGAGCTGCATTTCCAGCCCGCCCGCCTGACCCTCGACACCGCCGCCC TGGCAGATGGCTTTGAGGTGGTCTGCGCCTTCATCAATGACGAACTCGACGCGCCGGTGCTGCAGCGCCTGGCCGCCGCT GGCACGCGGTTGATCGCCCTGCGCTCGGCCGGCTACAACCACGTCGACCTGGCCGCCGCCCAGCGCTTGGGGCTGGCCGT GGTGCGGGTGCCGGCCTACTCGCCACACGCCGTTGCCGAGCATGCCGTGGCGCTCATCCTGGCACTCAACCGGCGTCTGC ATCGGGCCTACAACCGCACCCGCGAAGGTGACTTCACCCTGCACGGGCTGACCGGCTTCGACCTGCACGGGAAAACCGTC GGGGTGGTCGGTACCGGCCAGATCGGGGTCGCCTTCGCTCGCATCATGGCCGGTTTCGGCTGCCAGCTGCTGGCTTACGA CCCCTACCCCAACCCAGAGCTGCTGGCCCTTGGCGCCCGCTACCTGCCCCTGCCCGAGCTATTGCGCGAAGCCCGCATCA TCAGCCTGCACTGCCCACTGACCGAGCACACTCGCCACCTGATCAACGCGCAAAGCCTGGCCCAGTTGCAGCCCGGCGCC ATGCTGATCAACACCGGTCGCGGTGCGTTGGTCGACACCCCGGCGCTGATCGACGCACTGAAAAGCGGCCAGCTTGGCTA CCTGGGCCTGGACGTCTACGAAGAAGAAGCCCAACTGTTCTTCGAGGACCGCTCCGACCTGCCCTTGCAAGACGATGTGC TGGCTCGGCTGCTGACCTTCCCCAACGTGATCATCACCGCCCACCAGGCTTTCCTCACCCGCGAGGCGCTGGATGCCATT GCCGCGACCACACTGGACAACATCAACCGCTGGGCGGCAGGCAATCCACAGAACCTGGTGATGGGTTAA Protein sequence : MTHPRHALQRSSTMRALLFSSQHYDQESFTKAAGGTALELHFQPARLTLDTAALADGFEVVCAFINDELDAPVLQRLAAA GTRLIALRSAGYNHVDLAAAQRLGLAVVRVPAYSPHAVAEHAVALILALNRRLHRAYNRTREGDFTLHGLTGFDLHGKTV GVVGTGQIGVAFARIMAGFGCQLLAYDPYPNPELLALGARYLPLPELLREARIISLHCPLTEHTRHLINAQSLAQLQPGA MLINTGRGALVDTPALIDALKSGQLGYLGLDVYEEEAQLFFEDRSDLPLQDDVLARLLTFPNVIITAHQAFLTREALDAI AATTLDNINRWAAGNPQNLVMG |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| vanHB | YP_008394258.1 | VanH protein, D-specific alpha-keto acid dehydrogenase | Not tested | Not named | Protein | 2e-36 | 42 |
| EF2295 | NP_815952.1 | D-specific alpha-keto acid dehydrogenase | Not tested | Not named | Protein | 2e-36 | 42 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | AF130997.1.orf3.gene | Protein | 1e-35 | 42 |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | NC_005054.2598279.p0 | Protein | 2e-34 | 42 |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | NC_014475.1.orf2.gen | Protein | 2e-34 | 42 |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | AF310956.2.orf4.gene | Protein | 3e-37 | 42 |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | U35369.1.gene5.p01 | Protein | 1e-36 | 42 |
| ldhA | NP_743806.1 | D-lactate dehydrogenase | AF155139.2.orf4.gene | Protein | 1e-34 | 41 |
