Gene Information

Name : murD (PP_1335)
Accession : NP_743494.1
Strain : Pseudomonas putida KT2440
Genome accession: NC_002947
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1520740 - 1522092 bp
Length : 1353 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGAGCGTGTCTTTGATCGCTTCCGACCAATTCCGCATCGTTGTCGGCCTCGGCAAGAGCGGCATGTCCCTGGTTCGCTT
CCTGGCGAGCCGGGGCATTGCCTTTGCGGTCGCCGATACCCGCGAGCAGCCGCCGGAACTGGAAACCCTGCGCCGTGATT
ACCCGCAGGTGGAAGTGCGCTGTGGTGAACTGGACGTGGACTTCCTGTGCCGCGCCAACGAGCTGTACGTGAGCCCCGGC
CTGGCCTTGGCCACGCCGGCCTTGCAGCAGGCTGCCGCGCGTGGCGTGAAGCTGTCTGGCGACATAGAGCTGTTTGCTCG
CCATGCCAAGGCGCCGATCGTTGCCATCAGTGGTTCCAACGCCAAGAGCACCGTCACGACGCTGGTCGGTGAAATGGCCG
CCAAGGCCGGCAAACGCGTGGCCGTGGGCGGTAACCTCGGTACCCCGGCACTCGACCTGCTGGCCGATGACATCGAGCTG
TACGTGCTGGAGCTTTCCAGCTTCCAGCTGGAAACCACTGACCAGCTCAACGCCGAAGTGGCGACCGTTCTGAACATCAG
CGAAGACCACATGGACCGCTATAGCGGCCTTCCGGCCTACCACCTGGCCAAACACCGGATTTTCCGCGGTGCCCGCCAGG
TGGTGGTCAACCGCCAGGACGCCCTGAGCCGGCCGCTGCCGGTGGAAGGCCGTCCATGCTGGACCTTCGGCCTCAACCCG
CCCGACTTCAAAGCGTTTGGCCTGCGTGAAGTGGACGGTGAGAAATACCTGGCGTTCGAGTTCCAGACGCTGATGCCGGC
GCGTGAACTGAAGGTTCGCGGTGCTCACAACCAGAGTAACGCCCTGGCGGCGCTGGCCCTGGGGCATGCTGCCGGCCTGC
CGTTCGAGCCCATGCTGGAGGCTCTGCGCGAATTCGGTGGCCTGGCCCACCGGTGCCAGTGGGTACGCGAGCGTAATGGC
GTGAACTGGTACGACGATTCCAAAGCCACCAACGTCGGTGCAGCCCTGGCCGCCATCGAAGGCCTGGGCGCTGATATCGA
AGGCAAGTTGGTGCTGATCGCCGGTGGTGACGGCAAAGGTGCTGAATTCACTGCGCTGCGCGAGCCGGTCAAGCGTTTCT
GCCGCGCCGTGGTATTGCTTGGCCGTGATGCCGAGCGCCTGGCCGAGGCCTTGGGCGATGCCGTGCCACTGGTTCGGGTC
AAGACGCTTGACGATGCCGTACAGCAGTGTGCCGAACTGGCCCAGGCCGGCGATGCCGTGCTGCTGTCGCCAGCATGCGC
CAGCCTCGACATGTTCAAGAACTTCGAGGAACGGGGACGCCTGTTCGCCCAGGCAGCGGGAGGTCTTGCATGA

Protein sequence :
MSVSLIASDQFRIVVGLGKSGMSLVRFLASRGIAFAVADTREQPPELETLRRDYPQVEVRCGELDVDFLCRANELYVSPG
LALATPALQQAAARGVKLSGDIELFARHAKAPIVAISGSNAKSTVTTLVGEMAAKAGKRVAVGGNLGTPALDLLADDIEL
YVLELSSFQLETTDQLNAEVATVLNISEDHMDRYSGLPAYHLAKHRIFRGARQVVVNRQDALSRPLPVEGRPCWTFGLNP
PDFKAFGLREVDGEKYLAFEFQTLMPARELKVRGAHNQSNALAALALGHAAGLPFEPMLEALREFGGLAHRCQWVRERNG
VNWYDDSKATNVGAALAAIEGLGADIEGKLVLIAGGDGKGAEFTALREPVKRFCRAVVLLGRDAERLAEALGDAVPLVRV
KTLDDAVQQCAELAQAGDAVLLSPACASLDMFKNFEERGRLFAQAAGGLA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 5e-84 53
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 5e-84 53