Gene Information

Name : smpB (NGO0986)
Accession : YP_208083.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 957331 - 957783 bp
Length : 453 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGTTTATGGCTATTGCGAACAATAAAAAAGCATTTCACGATTTTTTCATTGAAGACCGGATTGAAGCCGGTTTGGTCTT
GGAAGGCTGGGAAGTCAAAGCAATCCGCGCCGCGCGCGTACAGCTTAAAGAGAGTTATATCTATTGGAAAAAAGATGCGT
TTTATCTGGTCGGCTGCCATATTACGGCTTTGCCTACGGCTTCGACACACATCAAACCGGATGCCGTACGTCCGCGCAAA
CTGTTATTAAAACAGTCGGAAATCAATAAGTTAATCGGAAAAACCGAACGTGCAGGTTACACCATCGTGCCGCTGGATTT
GCATTTTTCACGCGGAAAAATCAAGATGGAAATCGGTTTGGCAAAAGGTAAGAAACAGCACGATAAACGACAAAGTATGA
AGGAAGCCGACTGGAAACGCGAGAAACAGCGGTTGATTAAGCATACGCGCTGA

Protein sequence :
MFMAIANNKKAFHDFFIEDRIEAGLVLEGWEVKAIRAARVQLKESYIYWKKDAFYLVGCHITALPTASTHIKPDAVRPRK
LLLKQSEINKLIGKTERAGYTIVPLDLHFSRGKIKMEIGLAKGKKQHDKRQSMKEADWKREKQRLIKHTR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 9e-31 47
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 9e-23 46
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 1e-14 42