Gene Information

Name : NGO0915 (NGO0915)
Accession : YP_208023.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : dihydrolipoamide dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1249
EC number : 1.8.1.4
Position : 893178 - 894611 bp
Length : 1434 bp
Strand : -
Note : E3 component of 2-oxoglutarate dehydrogenase complex; catalyzes the oxidation of dihydrolipoamide to lipoamide

DNA sequence :
ATGTCTCAATATGATGTAGTAGTGATTGGTGCAGGTCCGGGCGGATACGTTGCCGCCATCCGTGCCGCACAACTGGGTTT
CAAAACTGCCTGTGTCGATGCAGGCGTTAACAAAGCAGGCAATGCCCCTGCATTGGGCGGTACTTGCTTGAACGTAGGCT
GTATCCCTTCTAAAGCCCTGTTGCAATCCAGCGAACATTTCCACGCTGCGCAACACGATTTTGCCGAACACGGTATCACT
GTCGGCGACGTAAAATTCGACGCGGCCAAAATGATTGAGCGCAAAGATGCCATCGTGACCAAACTGACCGGCGGCGTGAA
ATTCCTGTTCCAAAAAAACAAAGTAACCAGCCTGTTCGGTACTGCTTCCTTTGCCGGTAAAAATGGCGATGCTTACCAAA
TTGAAGTCGATAACAAAGGCGAGAAAACCGTTATCGAAGCCAAACACGTCATCGTAGCAACCGGTTCCGTACCGCGTCCG
TTGCCGCAAGTCGCTATCGACAACGTGAACGTATTGGACAACGAAGGCGCATTGAACCTGACTGAAGTACCTGCCAAACT
CGGCGTAATCGGTTCCGGTGTGATTGGTTTGGAAATGGGTTCCGTATGGAACCGCGTGGGTGCGGAAGTTACCATTCTTG
AAGCCGCGCCGACCTTCCTGGCTGCCGCCGACCAACAAATCGCCAAAGAAGCCTTCAAATACTTCACCAAAGAGCAAGGT
CTGAGCATCGAATTGGGTGTGAAAATCGGCGACATCAAGTCTGAAGGCAAAGGTGTTTCCGTTGCTTACGAAACTGCTGC
CGGCGAAGCCAAAACCGAAGTATTCGACAAACTGATCGTTGCCATCGGCCGTATTCCAAACACCAAAGGCCTGAACGCTG
AAGCCGTAGGCTTGGAAAAAGACGAGCGCGGCTTTATCAAAGTGGATGGCGAATGCCGTACCAACCTGCCTAACGTATGG
GCAATCGGCGACGTGGTTCGCGGCCCGATGTTGGCACACAAAGCCAGCGACGAAGGCGTTGCCGTTGCCGAGCGCATTGC
CGGTCAAAAACCGCATATCGACTTCAACAACGTACCGTTTGTGATTTACACCGACCCTGAAATCGCTTGGGTGGGTAAAA
CCGAAGAGCAGCTCAAAGCCGAAGGCGTGGAGTACAAAAAAGGTACTTCAGGTTTCGGTGCAAACGGCCGTGCATTGGCA
ATGGGCAAAGCCAAAGGTACGGTTAAAGTGTTGGCAGATGCCAAAACCGACCGTATCTTGGGCGTACACATGATCGGCCC
GGTTGTCAGCGAATTGGTTACCGAAGGCGTGACTGCGCTCGAATTCTTCGCCAGCAGCGAAGACATCGCCCGTATTATCC
ATGCCCACCCAACCTTGTCCGAAGTGGTTCACGAAGCTGCATTGGCGGCCGACAAACGCGCTTTGCACGGTTGA

Protein sequence :
MSQYDVVVIGAGPGGYVAAIRAAQLGFKTACVDAGVNKAGNAPALGGTCLNVGCIPSKALLQSSEHFHAAQHDFAEHGIT
VGDVKFDAAKMIERKDAIVTKLTGGVKFLFQKNKVTSLFGTASFAGKNGDAYQIEVDNKGEKTVIEAKHVIVATGSVPRP
LPQVAIDNVNVLDNEGALNLTEVPAKLGVIGSGVIGLEMGSVWNRVGAEVTILEAAPTFLAAADQQIAKEAFKYFTKEQG
LSIELGVKIGDIKSEGKGVSVAYETAAGEAKTEVFDKLIVAIGRIPNTKGLNAEAVGLEKDERGFIKVDGECRTNLPNVW
AIGDVVRGPMLAHKASDEGVAVAERIAGQKPHIDFNNVPFVIYTDPEIAWVGKTEEQLKAEGVEYKKGTSGFGANGRALA
MGKAKGTVKVLADAKTDRILGVHMIGPVVSELVTEGVTALEFFASSEDIARIIHAHPTLSEVVHEAALAADKRALHG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0077 NP_763632.1 dihydrolipoamide dehydrogenase component of pyruvate dehydrogenase E3 Not tested SCCpbp4 Protein 9e-67 42