|
Name : leuS (NGO0006) Accession : YP_207190.1 Strain : Neisseria gonorrhoeae FA 1090 Genome accession: NC_002946 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 6500 - 9136 bp Length : 2637 bp Strand : + Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGACCATGCAAGAACATTACCAGCCCGCCGCCATCGAGCCTGCGGCGCAGAAAAAATGGGACGACGCCCGTATTTCCAA CGTCTCCGAAGACGCTTCCAAACCCAAATATTATTGCCTTTCGATGTTCCCTTACCCTAGCGGCAAGCTGCATATGGGGC ATGTACGCAACTACACCATCGGCGACGTATTGAGCCGCTTCAAACTTTTAAACGGCTTCAACGTTATGCAGCCTATGGGT TGGGACGCGTTCGGCATGCCGGCGGAAAATGCGGCGATGAAAAACAACGTCGCCCCCGCCGCTTGGACCTACGACAACAT CGAATACATGAAAACCCAGCTCAAAAGCCTGGGTTTTGCGATTGACTGGGAACGCGAAGTCGCCACCTGCAAACCCGAAT ACTACCGCTGGGAACAATGGCTGTTTACCAAGCTGTTTGAAAAAGGCATCGTCTATCGCAAAAACGGAACGGTGAACTGG GACCCGGTCGACCAAACCGTCCTTGCCAACGAGCAAGTCATCGACGGACGCGGCTGGCGTTCGGGCGCGTTGATCGAAAA ACGCGAAATCCCGATGTATTACTTCAAAATTACGGATTACGCCGAAGAGCTGCTCAACGATTTGGACAAGCTGGAACACT GGCCGGAACAAGTCAAAACCATGCAGCGCAACTGGATCGGCAAATCTCGCGGCATGACCGTGCGCTTCGCCGTTTCAGAC GACAGCAAGCAAGGTTTGGAAGGCGATTACGCGAAATTCCTGCAAGTTTATACCACCCGCCCCGACACGCTGATGGGTGC GACTTATGTCGCTGTTGCCGCCGAACATCCGCTGGCAACAGCCGCAGCCGCCGACAAACCCGAATTGCAGGCATTTATCG CCGAATGCAAAGCCGGTTCGGTTGCCGAAGCCGATATGGCGACGATGGAGAAAAAAGGCGTGCCGACCGGCCGCTACGTC GTCAACCCGCTCAACGGCGACAAGCTGGAAGTGTGGATTGCCAACTATGTCTTGTGGGGCTACGGCGACGGCGCGGTGAT GGCTGTTCCGGCGCACGACGAACGCGATTTCGAGTTTGCCGCCAAATACAATCTGCCGAAAAAACAAGTCATTGCCGTCG GCGACAACGCATTCGACGCAAACCGATGGCAAGAATGGTACGGCGACAAAGAAAACGGCGTATTGGTCAACAGCGGCGAC TTGGACGGCTTGGATTTTCAGACGGCATTTGATGCCGTTGCCGCCAAGCTGCAAAGCCAAGGTGCGGGCGAACCGAAAAC CCAATACCGCCTGCGCGACTGGGGCATTTCGCGCCAACGCTACTGGGGCTGCCCGATTCCCATCGTCCATTGCGAAAAAT GCGGAGACGTTCCCGTCCCTGCCGACCAACTGCCCGTCGTCCTGCCTGAAAACGTCGTACCCGACGGTATGGGTTCGCCG CTGGCAAAAATGCCCGAGTTTTACGAAACTTCCTGCCCGTGCTGCGGCGGCGCGGCGAAACGCGAAACCGACACCATGGA CACCTTCATGGAGTCGAGCTGGTACTTCTTCCGCTATATGTCGCCCAAGTTTTCAGACGGCATGGTATCGGCAGAATCCG CGAAATACTGGGGCGCGGTCGACCAATACATCGGCGGCATCGAACACGCGATTTTGCACCTCCTGTACGCGCGCTTCTTC ACCAAACTGATGCGCGACGAAGGTTTGGTCAATGTTGACGAACCGTTTGAACGCCTGCTCACGCAAGGTATGGTCGTCTG CGAAACCTACTACCGCGAAAACGACAAAGGCGGCAAAGACTGGATCAACCCCGCCGATGTCGAGCTGACTTTCGATGACA AAGGCCGCCCCGTTTCCGCCGTCCTCAAAGCCGACGGACTGCCCGTCGTCATCAGCGGCACGGAAAAAATGTCCAAATCC AAAAACAACGGCGTCGATCCGCAAGAACTGATTAACGCCTACGGCGCGGACACCGCCCGCCTGTTCATGATGTTCGCCGC ACCGCCCGAACAGTCCCTCGAATGGAGCGACAGCGGCGTCGAAGGTGCACACCGCTTCCTGCGCCGTCTGTGGCGTACCG TTTACGAATACCTGAAGCAAGGCGGCGCGGTCAAAGCATTTGCAGGCAACCAAGACGGTTTGTCTAAAGAACTCAAAGAC CTGCGCCACAAACTGCATTCCACCACCGCCAAAGTCAGCGACGACTACGGCCGCCGCCAGCAGTTCAACACCGCCATCGC CGCCGTGATGGAACTGCTCAACCAATACGACAAAACCGACACCGGCAGCGAACAAGGCCGCGCCGTCGCCCAAGAAGTAT TGGAAGCCGCCGTACGCCTGTTGTGGCCCATCGTGCCGCACATCTGCGAAACCCTGTGGAGCGAATTGAACGGCGCGAAA CTGTGGGAAGCAGGCTGGCCGACAGTCGACGAAGCCGCCCTGGTCAAATCCGAAATCGAAGTGATGGTTCAAGTCAACGG CAAACTGCGCGGCAAAATCACCGTCGCCGCCGACGCCTCCAAAGCCGACCTCGAAGCCGCCGCACTCGCCAACGAAGGCG CAGTGAAATTCATGGAAGGCAAGCCTGCGAAGAAAATCATCGTCGTACCGGGCAGACTGGTGAACATCGTCGTCTAA Protein sequence : MTMQEHYQPAAIEPAAQKKWDDARISNVSEDASKPKYYCLSMFPYPSGKLHMGHVRNYTIGDVLSRFKLLNGFNVMQPMG WDAFGMPAENAAMKNNVAPAAWTYDNIEYMKTQLKSLGFAIDWEREVATCKPEYYRWEQWLFTKLFEKGIVYRKNGTVNW DPVDQTVLANEQVIDGRGWRSGALIEKREIPMYYFKITDYAEELLNDLDKLEHWPEQVKTMQRNWIGKSRGMTVRFAVSD DSKQGLEGDYAKFLQVYTTRPDTLMGATYVAVAAEHPLATAAAADKPELQAFIAECKAGSVAEADMATMEKKGVPTGRYV VNPLNGDKLEVWIANYVLWGYGDGAVMAVPAHDERDFEFAAKYNLPKKQVIAVGDNAFDANRWQEWYGDKENGVLVNSGD LDGLDFQTAFDAVAAKLQSQGAGEPKTQYRLRDWGISRQRYWGCPIPIVHCEKCGDVPVPADQLPVVLPENVVPDGMGSP LAKMPEFYETSCPCCGGAAKRETDTMDTFMESSWYFFRYMSPKFSDGMVSAESAKYWGAVDQYIGGIEHAILHLLYARFF TKLMRDEGLVNVDEPFERLLTQGMVVCETYYRENDKGGKDWINPADVELTFDDKGRPVSAVLKADGLPVVISGTEKMSKS KNNGVDPQELINAYGADTARLFMMFAAPPEQSLEWSDSGVEGAHRFLRRLWRTVYEYLKQGGAVKAFAGNQDGLSKELKD LRHKLHSTTAKVSDDYGRRQQFNTAIAAVMELLNQYDKTDTGSEQGRAVAQEVLEAAVRLLWPIVPHICETLWSELNGAK LWEAGWPTVDEAALVKSEIEVMVQVNGKLRGKITVAADASKADLEAAALANEGAVKFMEGKPAKKIIVVPGRLVNIVV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 8e-138 | 41 |
