Gene Information

Name : NGO0386 (NGO0386)
Accession : YP_207542.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.1
Position : 379010 - 380167 bp
Length : 1158 bp
Strand : -
Note : Best Blastp Hit: pir||A81158 cystathionine beta-lyase (EC 4.4.1.8) NMB0802 [similarity] - Neisseria meningitidis (group B strain MD58) >gi|7226035|gb|AAF41215.1| (AE002433) cystathionine gamma-synthase [Neisseria meningitidis MC58]; COG0626 Cystathionine

DNA sequence :
ATGAAATTCCCGACCCGTACCATCCATTCCGGCTACGATTGCGACGAACACAACCGCGCGCTGATGCCGCCGATTTATCA
AAACAGTATGTTTGCGCTGCACGAAATCGGCGAAAATGTGCCTTACCGTTATTCGCGCCTGAGCAACCCGACCCGTCAGA
TTTTGGAAGACACCGTTGCCGATTTGGAACACGGTGCGGCAGGTTTTGCGTTTTCCAGCGGTATGGCGGGGATTGATGCC
GTGTGGCGTACCTTCCTGCGCCCGGGCGATACCATCGTCGCGGTCGCCGATATTTACGGCGGCGCATATGACTTATTGGT
CGATGTTTATCAAAAATGGGGGGTGAACGTTGTTTTTGCCGATTTGGGCAATCCCGATAATTTGGACGAATTGCTCAAAG
CGCACAATGTCAAACTGGTTTGGCTGGAAATGCCGTCCAATCCGCTTTTACGCTTGGTAGACATCAAAGCCCTTGCAGCG
AAAGCCAAAGCAGCCGACGCGCTGGTCGGCATCGACAACACCTTTGCCACGCCGTATCTGCAACAGCCCTTGGATATGGG
TTGCGATTTTGCATTCCATTCCGCTACCAAATATTTGTGCGGCCATTCCGACGTATTGATGGGCATCGTCGTTGCCAAAA
CCAAAGAGCTGGCTCAGCCTTTGCACGATATGATGGTGCATACCGGCGCGATTGCAGGTCCGACGGACTGCTGGCTGGTG
TTGCGCGGCATCAAAACGCTTGCCCTGCGTATGGAGGCACACTGCAAAAACGCACTCGAAATTGCGCGCCGTTTGGAAGC
CCATCCTGCCATTGAAAAAGTGTTCCATCCCGGCCTGCCGTCTCACGAACATTACGCACTCGCCCAAGCGCAAATGCCCA
AAGGCATCGGCGGCGTGGTTACGGTTTATCTCAAAAACGACACGCGCGAAGCGGCAAACAGCGTGATTAAAAACATGAAA
CTGGTCAAAATGACCTCCAGCCTCGGCGGCGTGGAAAGTCTGGTCAACCATTGCTATTCCCAATCTCACAGCGGCGTGCC
GCATAATGTGAAAATGGAAATGGGCATCAGGGTCGGACTCCTGCGCTTCTCCATCGGTATTGAAGACGTAGATGATATTT
GGAACGATATTTCCGCCGCACTCGATACAACTTTGTAA

Protein sequence :
MKFPTRTIHSGYDCDEHNRALMPPIYQNSMFALHEIGENVPYRYSRLSNPTRQILEDTVADLEHGAAGFAFSSGMAGIDA
VWRTFLRPGDTIVAVADIYGGAYDLLVDVYQKWGVNVVFADLGNPDNLDELLKAHNVKLVWLEMPSNPLLRLVDIKALAA
KAKAADALVGIDNTFATPYLQQPLDMGCDFAFHSATKYLCGHSDVLMGIVVAKTKELAQPLHDMMVHTGAIAGPTDCWLV
LRGIKTLALRMEAHCKNALEIARRLEAHPAIEKVFHPGLPSHEHYALAQAQMPKGIGGVVTVYLKNDTREAANSVIKNMK
LVKMTSSLGGVESLVNHCYSQSHSGVPHNVKMEMGIRVGLLRFSIGIEDVDDIWNDISAALDTTL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-60 44
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 6e-61 43