Gene Information

Name : NGO2041 (NGO2041)
Accession : YP_209061.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 2011464 - 2013365 bp
Length : 1902 bp
Strand : +
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACTACGCCAAAAAAAACCGCCAAAATTTCCGGCAACGAAGCGCGCGAACTTTCCGACTTGAGCGAAGACATCGGCAT
CCGCTTCAAATATCAGAACTCCGAACGCGTGTATCTGCAAGGCAGCCGCGACGACATCCGCGTGCCTTTGCGCGAAATCC
GTCAGGACGACACCTACACGGCGCAAGGTACGGAAGCCAACCCGCCTATTCCGGTGTACGACACCAGCGGCGCATACGGC
GATCCGGCGGCGCACATCGACCTGAAACAAGGCCTGCCGCACATCCGCACGGCGTGGCTGGACGAACGCGGCGATACCGA
AATCCTGCCCAAGCTCTCCAGCGAATACGGCATCGAACGTGCGCACGATCCGAAAACCGCCCATCTGCGCTTCAACCAAA
TCACCCGCCCGCGCCGTGCCAAAGCCGGCCGCAATGTAACCCAGCTCCATTACGCCCGCCAAGGCATTATCACGCCCGAA
ATGGAGTTCGCCGCCATACGCGAACGCATGAAGCTGGACGAGCTTTTCAGACGGCCTGAATACGCCAAGCTCTTGAAACA
GCACACAGGGCAAAGTTTCGGTGCGAACATCCCGACCCGTCCCGACCAAATCACCCCCGAATTCGTGCGCCAAGAAATCG
CCGCCGGACGCGCGATTATCCCCGCCAACATCAACCACCCCGAACTCGAACCGATGATTATCGGCCGCAACTTCCGCGTC
AAAATCAACGGCAACTTGGGCAATTCCGCCGTAACCTCCAGCCTGACCGAAGAAGTCGAAAAAATGGTGTGGTCGCTGCG
TTGGGGCGCGGACACGATTATGGACTTATCCACAGGCGCGCACATCCACGAAACGCGCGAATGGATTATCCGCAACGCGC
CCGTCCCCATCGGCACAGTGCCGATTTACCAAACTTTGGAAAAAACCGGCGGCATCGCCGAAGATTTGACTTGGGATTTG
TTCCGCGACACCTTAATCGAGCAGGCGGAACAAGGCGTGGACTATTTCACCATACACGCGGGCGTGTTGCTGCGTTATGT
GCCGATGACCGCCAACCGCCTCACCGGCATCGTATCGCGCGGCGGTTCGATTATGGCGAAATGGTGTTTGGCACATCATC
GGGAAAACTTCCTCTACACGCATTTCGACGAAATCTGCGAAATCATGAAGGCGTATGACGTATCGTTCAGCTTGGGCGAC
GGCCTGCGCCCCGGCTGCATTGCCGATGCCAACGACGAATCCCAATTCGCCGAATTGCACACCTTGGGCGAATTGACCGA
TAAAGCGTGGAAACACGACGTACAAGTCATGATCGAAGGCCCCGGCCATGTGCCGCTGCAACGCGTCAAAGAAAATATGA
CCGAAGAGTTGCAACACTGCTTTGAAGCACCGTTTTACACACTCGGCCCGCTCGTTACCGACATCGCCCCCGGCTACGAC
CACATCACTTCGGGCATAGGCGCGGCCAATATCGGCTGGTACGGCACGGCGATGCTTTGTTACGTTACCCCCAAAGAACA
TTTGGGGCTGCCCGACAAAGAAGACGTGCGCACCGGCATCATCACCTACAAACTCGCCGCCCACGCCGCCGACCTCGCCA
AAGGCTGGCCGGGCGCGCAATTACGCGACAACGCCCTGAGCAAGGCGCGTTTCGAATTCCGCTGGCGCGACCAATTCCGC
TTAAGCCTCGACCCCGAACGCGCCGAGAGCTTCCACGACGAAACCCTGCCCGCCGAAGGCGCGAAAATCGCCCATTTTTG
CTCAATGTGCGGCCCCAAATTTTGCTCGATGAAAATCACGCAGGAAGTGCGCGACTACGCCGACAAGCAAAAAGCCCAAC
GGCAGGGTATGGAGGAAAAAGCGGTCGAGTTCGTCAAAAAAGGCGCGAAGATTTACAGTTGA

Protein sequence :
MTTPKKTAKISGNEARELSDLSEDIGIRFKYQNSERVYLQGSRDDIRVPLREIRQDDTYTAQGTEANPPIPVYDTSGAYG
DPAAHIDLKQGLPHIRTAWLDERGDTEILPKLSSEYGIERAHDPKTAHLRFNQITRPRRAKAGRNVTQLHYARQGIITPE
MEFAAIRERMKLDELFRRPEYAKLLKQHTGQSFGANIPTRPDQITPEFVRQEIAAGRAIIPANINHPELEPMIIGRNFRV
KINGNLGNSAVTSSLTEEVEKMVWSLRWGADTIMDLSTGAHIHETREWIIRNAPVPIGTVPIYQTLEKTGGIAEDLTWDL
FRDTLIEQAEQGVDYFTIHAGVLLRYVPMTANRLTGIVSRGGSIMAKWCLAHHRENFLYTHFDEICEIMKAYDVSFSLGD
GLRPGCIADANDESQFAELHTLGELTDKAWKHDVQVMIEGPGHVPLQRVKENMTEELQHCFEAPFYTLGPLVTDIAPGYD
HITSGIGAANIGWYGTAMLCYVTPKEHLGLPDKEDVRTGIITYKLAAHAADLAKGWPGAQLRDNALSKARFEFRWRDQFR
LSLDPERAESFHDETLPAEGAKIAHFCSMCGPKFCSMKITQEVRDYADKQKAQRQGMEEKAVEFVKKGAKIYS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
thiC YP_001598318.1 thiamine biosynthesis protein ThiC Not tested MDA Protein 0.0 98
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 0.0 70
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 0.0 70