Gene Information

Name : murD (NGO1535)
Accession : YP_208583.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 1507328 - 1508665 bp
Length : 1338 bp
Strand : -
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGACTTTCCAAAACAAAAAAATCCTCGTCGCCGGACTTGGCGGCACGGGTATTTCCATGATTGCCTATCTGCGCAAAAA
CGGCGCGGAGGTTGCCGCTTATGATGCGGAGCTGAAAGCCGAGCGCGTGGCGCAAATCGGTAAGATGTTTGACGGGCTGG
TGTTTTACACGGGTCGTCTGAAAGATGCGTTGGACAACGGTTTCGATATTCTGGCGCTCAGTCCCGGCATCAGCGAGCGG
CAGCCGGATATCGAGGCGTTCAAGCAAAACGGCGGGCGCGTGCTAGGCGACATCGAATTGCTGGCGGACATTGTGAACCG
CCGCGGCGACAAGGTGATTGCGATTACCGGCAGCAACGGCAAAACCACGGTAACGAGCCTGGTCGGCTATCTCTGCATCA
AGTGCGGGCTGGATACCGTCATTGCGGGCAATATCGGTACGCCGGTTTTGGAGGCAGAATTGCAGCGCGAAGGCAAAAAG
GCGGACGTGTGGGTGTTGGAGCTTTCCAGCTTCCAACTGGAAAACACCGAAAGCCTGCGCCCGACTGCGGCGACGGTGAT
GAACATTTCCGAAGACCATCTCGACCGCTACGACGATTTGCTCGACTACGCGCATACCAAAGCCGAGATTTTCCGTGGCG
ATGGAGTGCAGGTTTTGAATGCGGACGACGTGTTCTGCCGCGCCATGAAACGGGCAGGGCGTGAAGTGAAACGGTTTTCC
TTGGAACACGAAGCCGATTTTTGGTTGGAACGCGGGACGGGCTGTTTAAAACAAGGCAATGAAGATTTGATTTCTACGCA
AGACATCCCGCTGCAAGGTTTGCACAACGCCGCCAACGTTATGGCTGCCGTGGCTTTGTGCGAGGCCGTCGGTTTGCCGC
GCGAAGCATTGCTGGAACACGTCAAAACCTTCCAAGGCTTGCCGCACCGTGTGGAAAAAATCGGCGAGAAAAACGGCGTG
GTATTCATCGACGACAGCAAAGGCACGAATGTCGGCGCGACCGCCGCCGCGATTGCCGGTTTGCAAAACCCGCTCTTCGT
GATTTTGGGCGGCATGGGCAAAGGGCAGGACTTCACGCCCCTGCGCGACGCGTTGAAAGATAAGGCAAAAGGCGTGTTCC
TGATCGGCGTCGATGCGCCGCAAATCCGCCGCGATTTGGACGGCTGCGGCTTGAACCTGACCGACTGCGTCACTTTGGAA
GAGGCGGTTCAGACGGCATACGCCCAAGCCGAAGCGGGCGATATTGTCTTGCTCAGCCCCGCCTGCGCGAGTTTCGATAT
GTTTAAAGGCTACGCGCACCGTTCGGAAGTGTTTATCGAAGCGTTTAAGGCTTTGTGA

Protein sequence :
MTFQNKKILVAGLGGTGISMIAYLRKNGAEVAAYDAELKAERVAQIGKMFDGLVFYTGRLKDALDNGFDILALSPGISER
QPDIEAFKQNGGRVLGDIELLADIVNRRGDKVIAITGSNGKTTVTSLVGYLCIKCGLDTVIAGNIGTPVLEAELQREGKK
ADVWVLELSSFQLENTESLRPTAATVMNISEDHLDRYDDLLDYAHTKAEIFRGDGVQVLNADDVFCRAMKRAGREVKRFS
LEHEADFWLERGTGCLKQGNEDLISTQDIPLQGLHNAANVMAAVALCEAVGLPREALLEHVKTFQGLPHRVEKIGEKNGV
VFIDDSKGTNVGATAAAIAGLQNPLFVILGGMGKGQDFTPLRDALKDKAKGVFLIGVDAPQIRRDLDGCGLNLTDCVTLE
EAVQTAYAQAEAGDIVLLSPACASFDMFKGYAHRSEVFIEAFKAL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 5e-57 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 5e-57 41