Gene Information

Name : hemC (NGO0146)
Accession : YP_207316.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : porphobilinogen deaminase
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0181
EC number : 2.5.1.61
Position : 153500 - 154435 bp
Length : 936 bp
Strand : +
Note : transformation of porphobilinogen to hydroxymethylbilane in porphyrin biosynthesis

DNA sequence :
ATGAACCCGAAAAAACTTGTTATCGCCAGCCGCGAAAGCCTGCTTGCCATGTGGCAGGCGAAACATATCCAAGGCCGTCT
GAAGGCGCTGTATCCCGATTGCGAAGTCGAAATTTTGGGCATGACCACGCGCGGCGACCGGATTTTGGACAGAACTTTGT
CAAAAGTCGGCGGGAAAGGCTTGTTTGTCAAAGAGTTGGAACAATCCCTTCAAGACGGGCGCGCCGATTTGGCGGTGCAT
TCGATTAAGGACGTGCCGATGGATTTGCCCGAAGGCTTCGCCCTTGCCGCCATCAGCGAACGCGCCAATCCGTTTGACGC
GTTTGTGTCCAACCGATACGCGCGTTTGGAAGAAATGCCCGAAGGCGCGGTTGTCGGCACATCCAGCCTGCGCCGCGAAG
CCCAGTTGCGCGCGCGCTATCCGCATTTGGTAATTAAACCCCTGCGCGGCAATGTACAAACCCGTTTGTCCAAACTCGAC
AACGGCGAATACGATGCAATTATCTTGGCTGCCGCCGGGTTGCAGCGTCTGGAATTGGATGAACGCATCCGCATGATTTT
GTCGGAATCCGACAGCCTGCCTGCCGCCGGACAAGGCGCATTGGGTATTGAAATTGCCACGCATCGCGAAGATTTGTACG
AAGTCTTGAAGCCGTTAAACCACGATACCACACACGCCTGCGTTACCGCCGAACGCGCTTTGGCGCGCGCTTTGGGCGGA
AGCTGCCAAGTGCCGCTGGCCGCGTATTGCACTGAAGAAAACGGGCTGCTGATCTTGCGCGGATTGGTCGGGCATCCCGA
CGGATCGATTGTGTTGCAGGCGGACGCGCAAGCCCCTGCCGGATATGCCGATGCGCTTGGACGTGCGGTTGCCAAAAAAC
TGGCGGACGACGGTGCGCAGGAATTGATTGGAGCAGTATTGAATACGGAAAATTGA

Protein sequence :
MNPKKLVIASRESLLAMWQAKHIQGRLKALYPDCEVEILGMTTRGDRILDRTLSKVGGKGLFVKELEQSLQDGRADLAVH
SIKDVPMDLPEGFALAAISERANPFDAFVSNRYARLEEMPEGAVVGTSSLRREAQLRARYPHLVIKPLRGNVQTRLSKLD
NGEYDAIILAAAGLQRLELDERIRMILSESDSLPAAGQGALGIEIATHREDLYEVLKPLNHDTTHACVTAERALARALGG
SCQVPLAAYCTEENGLLILRGLVGHPDGSIVLQADAQAPAGYADALGRAVAKKLADDGAQELIGAVLNTEN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00327 YP_008207792.1 Porphobilinogen deaminase Not tested AbaR25 Protein 5e-68 55
BJAB0868_00331 YP_008211657.1 Porphobilinogen deaminase Not tested AbaR26 Protein 5e-68 55