Gene Information

Name : NGO1335 (NGO1335)
Accession : YP_208397.1
Strain : Neisseria gonorrhoeae FA 1090
Genome accession: NC_002946
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 1294170 - 1295465 bp
Length : 1296 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATATCCAATTGCTCCGCAGCAACACCGCCGCCGTTGCCGAACGGCTTGCACGGCGCGGTTATGACTTTGATAC
CGCACGTTTTGACGCACTGGAAGAACGACGCAAGTCCGTTCAGGTGAAAACCGAAGAACTACAAGCCTCGCGCAACAGCA
TTTCCAAACAAATCGGCGCACTGAAAGGTCAGGGCAAACATGAAGAGGCGCAGGCGGCCATGGATCAAGTCGCCCAAATC
AAAACCGATTTGGAACAGGCTGCCGCCGATTTGGATGCCGTTCAAAAAGAATTGGACGCATGGTTGTTGAGCATACCTAA
CCTGCCGCACGAAAGCGTACCTCCCGGTAAAGACGAAACCGAAAACGTCGAAGTCCGCAAAGTCGGTACGCCGCGCGAAT
TTGATTTTGAAATCAAAGATCATGTCGATTTGGGCGAGCCTTTGGGCTTGGATTTCGAAGGCGGCGCGAAACTTTCCGGC
GCACGATTTACCGTGATGCGCGGACAAATCGCCCGTCTGCACCGCGCCTTGGCGCAATTCATGCTCGATACGCACATGCT
GCAACACGGCTACACCGAGCATTACACGCCTTATATCGTTGACGATACGACGCTGCAAGGCACAGGTCAGCTGCCCAAAT
TTGCAGAAGATTTGTTCCACGTTACCCGCGGCGGCGATGAAACCAAAACCACGCAATATCTGATTCCGACAGCCGAAGTT
ACCCTGACCAATACCGTTGCCGGCAGCATTATCCCGTCCGAACAACTGCCGCTGAAGCTGACCGCGCATTCGCCCTGTTT
CCGCAGTGAAGCGGGATCATACGGCAAAGACACGCGCGGCCTAATCCGCCAGCACCAGTTCGACAAAGTAGAAATGGTAC
AAATCGTTCATCCCGAAAAATCATACGGCGCGCTGGAAGAAATGGTCGGCCATGCCGAAAACATCCTGAAGGCTTTGGAA
CTGCCCTACCGCGTGATTACCCTGTGTACCGGCGACATGGGTTTCAGCGCGGCCAAAACGTATGACTTGGAAGTTTGGGT
TCCCGCACAAAATACCTACCGCGAAATCTCAAGCTGCTCCAACTGCGAAGATTTCCAAGCACGCCGCATGAAGGCGCGTT
TCAAAGACGAAAACGGCAAAAACCGCTTGGTACATACCTTAAACGGCTCCGGTTTGGCAGTCGGTCGCACTTTGGTCGCG
GTTTTGGAAAACCATCAAAACGCCGACGGCAGCATCAATATCCCCGCCGCACTGCAACCGTATATGGGCGGTGTTACCAA
GTTGGAAGTGAAATAA

Protein sequence :
MLDIQLLRSNTAAVAERLARRGYDFDTARFDALEERRKSVQVKTEELQASRNSISKQIGALKGQGKHEEAQAAMDQVAQI
KTDLEQAAADLDAVQKELDAWLLSIPNLPHESVPPGKDETENVEVRKVGTPREFDFEIKDHVDLGEPLGLDFEGGAKLSG
ARFTVMRGQIARLHRALAQFMLDTHMLQHGYTEHYTPYIVDDTTLQGTGQLPKFAEDLFHVTRGGDETKTTQYLIPTAEV
TLTNTVAGSIIPSEQLPLKLTAHSPCFRSEAGSYGKDTRGLIRQHQFDKVEMVQIVHPEKSYGALEEMVGHAENILKALE
LPYRVITLCTGDMGFSAAKTYDLEVWVPAQNTYREISSCSNCEDFQARRMKARFKDENGKNRLVHTLNGSGLAVGRTLVA
VLENHQNADGSINIPAALQPYMGGVTKLEVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 4e-101 55