Gene Information

Name : clpC (Mb3627c)
Accession : NP_857266.1
Strain : Mycobacterium bovis AF2122/97
Genome accession: NC_002945
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease ATP-binding subunit CLPC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : 3.4.-.-
Position : 3981399 - 3983945 bp
Length : 2547 bp
Strand : -
Note : -

DNA sequence :
ATGTTCGAACGATTTACCGACCGTGCCCGCAGGGTCGTCGTCCTGGCTCAGGAAGAGGCCAGGATGCTCAACCACAACTA
CATCGGCACCGAGCACATTCTTTTAGGCCTGATCCATGAAGGGGAAGGCGTTGCCGCCAAGTCACTGGAGTCGTTGGGGA
TCTCGCTGGAAGGTGTGCGCAGTCAGGTCGAGGAGATCATCGGCCAGGGCCAGCAGGCGCCGTCTGGGCACATTCCGTTT
ACCCCCCGCGCCAAAAAGGTCCTCGAGCTGAGCTTGCGTGAAGCGCTGCAGCTTGGCCACAACTACATCGGGACCGAACA
CATTTTGCTGGGCCTCATCCGAGAGGGTGAAGGCGTGGCCGCCCAGGTGCTGGTCAAGCTGGGCGCCGAGCTGACCCGGG
TGCGCCAGCAGGTGATCCAGCTGCTCTCCGGTTACCAAGGCAAGGAGGCCGCCGAAGCCGGCACCGGCGGCCGCGGGGGA
GAGTCCGGCTCTCCGTCTACGTCCTTGGTGCTCGACCAGTTCGGCCGCAACCTCACGGCGGCGGCGATGGAAGGCAAACT
GGACCCGGTCATCGGCCGCGAGAAGGAAATCGAGCGGGTCATGCAGGTGCTCTCTCGGCGCACCAAGAACAACCCGGTGC
TGATCGGCGAGCCCGGCGTCGGCAAGACCGCGGTCGTCGAAGGACTGGCGCAGGCCATCGTGCACGGCGAGGTGCCCGAG
ACGCTCAAGGACAAGCAGCTCTACACGCTGGATCTGGGATCGCTGGTGGCGGGTAGCCGCTACCGCGGTGACTTCGAGGA
ACGCCTCAAGAAGGTGCTCAAGGAGATCAACACCCGCGGTGACATCATCCTGTTTATCGACGAGCTGCACACCTTGGTCG
GTGCTGGAGCCGCCGAGGGCGCGATCGACGCCGCCTCGATCCTGAAACCGAAGCTCGCTCGCGGTGAACTGCAAACGATC
GGCGCCACCACGCTCGACGAATACCGCAAGTACATCGAGAAGGACGCCGCGCTGGAGCGCCGCTTCCAGCCGGTGCAGGT
GGGTGAGCCGACGGTGGAGCACACCATCGAGATCCTCAAGGGCCTGCGGGACCGGTACGAGGCGCACCACCGGGTGTCGA
TCACCGATGCGGCGATGGTGGCCGCCGCGACCCTGGCCGACCGCTACATCAACGACCGGTTCCTGCCCGACAAGGCGATC
GACCTGATCGACGAGGCGGGTGCTCGGATGCGGATTCGTCGCATGACCGCACCGCCAGACCTACGCGAGTTCGATGAGAA
GATCGCCGAGGCTCGTCGGGAGAAGGAATCGGCTATCGACGCCCAGGACTTCGAGAAGGCCGCCAGCCTGCGCGACCGGG
AGAAGACACTGGTCGCACAGCGTGCTGAGCGCGAAAAGCAGTGGCGTTCAGGCGATCTTGACGTGGTCGCGGAGGTCGAC
GACGAGCAGATCGCCGAGGTGCTGGGCAACTGGACCGGTATCCCGGTGTTCAAGCTCACCGAGGCCGAGACCACCCGGCT
GTTGCGGATGGAAGAAGAGCTGCACAAGCGGATCATCGGGCAAGAGGACGCCGTCAAGGCCGTTTCCAAGGCCATCCGGC
GTACCCGGGCCGGGCTGAAAGACCCCAAGCGCCCGTCGGGCTCGTTCATCTTCGCCGGCCCGTCCGGTGTCGGTAAGACC
GAACTGTCCAAGGCGCTGGCCAACTTCTTGTTCGGTGACGACGACGCGCTTATTCAGATTGACATGGGTGAATTCCACGA
CCGGTTCACCGCGTCGCGGCTATTCGGCGCGCCGCCCGGATACGTCGGCTACGAGGAGGGCGGCCAACTCACCGAGAAGG
TGCGGCGCAAGCCGTTCTCGGTGGTGCTGTTCGACGAGATCGAGAAGGCGCATCAGGAGATCTACAACAGCCTGCTGCAG
GTGCTCGAGGATGGCCGGCTCACCGACGGGCAGGGCCGCACGGTGGACTTCAAGAACACCGTGCTGATCTTTACGTCCAA
TCTGGGCACCTCCGACATCTCTAAGCCGGTCGGTCTGGGCTTTTCCAAGGGCGGCGGTGAGAACGACTACGAGCGGATGA
AACAGAAGGTCAACGACGAGCTGAAGAAACACTTCCGCCCGGAGTTCCTCAACCGCATCGACGACATCATCGTCTTCCAC
CAGCTGACCCGCGAGGAGATCATCCGGATGGTCGACCTGATGATCAGCCGGGTCGCCGGCCAGCTCAAGAGCAAGGACAT
GGCGCTGGTGCTGACCGATGCGGCCAAGGCGCTGCTGGCCAAGCGTGGCTTCGACCCGGTGCTGGGGGCCCGCCCGTTGC
GGCGCACCATCCAGCGTGAGATCGAAGATCAGCTCTCGGAGAAGATCCTCTTCGAGGAGGTCGGGCCGGGTCAGGTGGTC
ACCGTCGACGTGGACAACTGGGACGGTGAAGGTCCCGGCGAGGACGCGGTGTTCACCTTCACCGGTACCCGCAAGCCGCC
GGCCGAGCCGGATCTGGCCAAGGCTGGAGCGCACAGCGCGGGCGGCCCGGAGCCGGCCGCGCGGTAG

Protein sequence :
MFERFTDRARRVVVLAQEEARMLNHNYIGTEHILLGLIHEGEGVAAKSLESLGISLEGVRSQVEEIIGQGQQAPSGHIPF
TPRAKKVLELSLREALQLGHNYIGTEHILLGLIREGEGVAAQVLVKLGAELTRVRQQVIQLLSGYQGKEAAEAGTGGRGG
ESGSPSTSLVLDQFGRNLTAAAMEGKLDPVIGREKEIERVMQVLSRRTKNNPVLIGEPGVGKTAVVEGLAQAIVHGEVPE
TLKDKQLYTLDLGSLVAGSRYRGDFEERLKKVLKEINTRGDIILFIDELHTLVGAGAAEGAIDAASILKPKLARGELQTI
GATTLDEYRKYIEKDAALERRFQPVQVGEPTVEHTIEILKGLRDRYEAHHRVSITDAAMVAAATLADRYINDRFLPDKAI
DLIDEAGARMRIRRMTAPPDLREFDEKIAEARREKESAIDAQDFEKAASLRDREKTLVAQRAEREKQWRSGDLDVVAEVD
DEQIAEVLGNWTGIPVFKLTEAETTRLLRMEEELHKRIIGQEDAVKAVSKAIRRTRAGLKDPKRPSGSFIFAGPSGVGKT
ELSKALANFLFGDDDALIQIDMGEFHDRFTASRLFGAPPGYVGYEEGGQLTEKVRRKPFSVVLFDEIEKAHQEIYNSLLQ
VLEDGRLTDGQGRTVDFKNTVLIFTSNLGTSDISKPVGLGFSKGGGENDYERMKQKVNDELKKHFRPEFLNRIDDIIVFH
QLTREEIIRMVDLMISRVAGQLKSKDMALVLTDAAKALLAKRGFDPVLGARPLRRTIQREIEDQLSEKILFEEVGPGQVV
TVDVDNWDGEGPGEDAVFTFTGTRKPPAEPDLAKAGAHSAGGPEPAAR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 81

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC NP_857266.1 ATP-dependent Clp protease ATP-binding subunit CLPC VFG0079 Protein 0.0 60
clpC NP_857266.1 ATP-dependent Clp protease ATP-binding subunit CLPC VFG0080 Protein 7e-140 51