Gene Information

Name : thiC (MAP3913c)
Accession : NP_962847.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : thiamine biosynthesis protein ThiC
Function : -
COG functional category : H : Coenzyme transport and metabolism
COG ID : COG0422
EC number : -
Position : 4375480 - 4377102 bp
Length : 1623 bp
Strand : -
Note : required for the synthesis of the hydromethylpyrimidine moiety of thiamine

DNA sequence :
ATGACCGCAATTGTCGAACCGAGCGTGACCACCGGGCCCATCGCGGGCAGCAGCAAGGTCTACCGCGAACTGGACGGGGT
GCCCGGTGCCCGGGTTCCGTTCCGCCGCGTCCACCTGTCCACCGGCGACCACTTCGACCTCTACGACACCTCCGGCCCCT
ACACCGATCCGGACGCGACGATCGACCTGACGGCCGGGCTGCCGGCGCGGCCGGGCCGGGTGCGCGACCGCGGCACCCAG
CTGCAGCGGGCCCGGGCCGGCGAGATCACCGCGGAGATGGCGTTCATCGCCGCCCGCGAGGGCATGCCGGCGGAGTTGGT
GCGCGACGAGGTCGCCCGCGGCCGCGCCGTGATCCCGGCCAACCACAACCATCCCGAGATCGAGCCGATGATCATCGGCA
AGGCGTTCGCCACCAAGGTCAATGCGAACATCGGCAACTCGGCGGTGACCAGCTCGATCGCCGAGGAGGTCGACAAGATG
GTGTGGGCCACCCGGTGGGGTGCGGACACCATCATGGACCTGTCCACCGGCAAGAACATCCACGAGACCCGCGAATGGAT
CCTGCGTAATTCGCCGGTGCCGGTCGGCACCGTACCGATCTATCAGGCGCTGGAGAAGGTCAAGGGCGATCCGACGCTGC
TGACCTGGGAGATCTACCGCGACACCGTGATCGAGCAGTGCGAGCAGGGCGTGGACTACATGACCGTGCACGCCGGTGTG
CTGCTGCGCTACGTGCCGCTGACCGCCAAGCGGGTCACCGGCATCGTGTCCCGCGGCGGGTCGATCATGGCCGCCTGGTG
CCTGGCGCATCACCGAGAGTCGTTCCTGTACACCAACTTCGACGAGCTGTGCGAGATCTTCGCCCGCTATGACGTCACCT
TCTCCCTGGGCGACGGCCTGCGGCCCGGCTCGATCGCCGACGCCAACGACGCCGCGCAGTTCGCCGAGCTGCGCACCCTG
GGCGAGCTGACCAAGATCGCGAAATCCCATGGCGTGCAAGTGATGATCGAAGGCCCCGGGCACGTTCCGATGCACAAGAT
CGTGGAGAACGTGCGGCTGGAGGAGGAGTGGTGCGAGGAGGCCCCGTTCTACACGCTGGGCCCGCTGGCCACCGACATCG
CCCCGGCCTACGACCACATCACCTCGGCGATCGGCGCGGCCATCATCGCCCAGGCGGGCACGGCGATGCTGTGCTACGTG
ACCCCGAAGGAGCACCTGGGGCTGCCGGACCGCAAGGACGTCAAGGACGGCGTGATCGCCTACAAGATCGCCGCGCACGC
CGGCGACCTGGCCAAGGGGCACCCGCACGCGCAGCAGCGCGATAATGCGTTGAGCCAGGCGCGTTTCGAGTTCCGCTGGA
ACGACCAGTTCGCGCTGTCGCTGGATCCCGACACCGCGCGGGAGTATCACGACGAGACGCTGCCCGCCGAGCCCGCCAAG
ACCGCGCACTTCTGCTCGATGTGCGGGCCGAAGTTCTGCTCGATGCGCATCACCCAGGACGTCCGCGACTATGCGGCCAA
GCACGGGCTGGACAGCGAGGAAGCGATCGAGGCGGCCATGGCCGACAAGTCTCGCGAGTTCGCCGAGCACGGCAACCGGG
TGTATCTACCGCTGGCACAGTGA

Protein sequence :
MTAIVEPSVTTGPIAGSSKVYRELDGVPGARVPFRRVHLSTGDHFDLYDTSGPYTDPDATIDLTAGLPARPGRVRDRGTQ
LQRARAGEITAEMAFIAAREGMPAELVRDEVARGRAVIPANHNHPEIEPMIIGKAFATKVNANIGNSAVTSSIAEEVDKM
VWATRWGADTIMDLSTGKNIHETREWILRNSPVPVGTVPIYQALEKVKGDPTLLTWEIYRDTVIEQCEQGVDYMTVHAGV
LLRYVPLTAKRVTGIVSRGGSIMAAWCLAHHRESFLYTNFDELCEIFARYDVTFSLGDGLRPGSIADANDAAQFAELRTL
GELTKIAKSHGVQVMIEGPGHVPMHKIVENVRLEEEWCEEAPFYTLGPLATDIAPAYDHITSAIGAAIIAQAGTAMLCYV
TPKEHLGLPDRKDVKDGVIAYKIAAHAGDLAKGHPHAQQRDNALSQARFEFRWNDQFALSLDPDTAREYHDETLPAEPAK
TAHFCSMCGPKFCSMRITQDVRDYAAKHGLDSEEAIEAAMADKSREFAEHGNRVYLPLAQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB0868_00321 YP_008211647.1 Thiamine biosynthesis protein ThiC Not tested AbaR26 Protein 4e-158 61
BJAB07104_00317 YP_008207782.1 Thiamine biosynthesis protein ThiC Not tested AbaR25 Protein 4e-158 61