Gene Information

Name : smpB (MAP3170c)
Accession : NP_962104.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 3522068 - 3522577 bp
Length : 510 bp
Strand : -
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
GTGGCCAAGGGTTCCGGCCGGGCCAAAGCGGCGGGCGGCAAAGGTGGCAGCAAACAGATCATTGCCACCAATCGCAAAGC
GCGGCACAACTATTCGATCATCGAAACGTACGAGGCCGGGGTGGCGTTGCAAGGAACCGAGGTCAAAAGCCTGCGGGAGG
GCCAAGCGTCGTTAGCTGACGCGTTCGCAACGATCGACGACGGTGAAGTCTGGTTGCGCAACTTGTACATCCCGGAGTAT
CAACACGGTAGCTGGACCAATCACGACCCACGCCGGAACCGAAAGTTGTTGTTACATAGGCAACAAATCGACAGACTGGT
CGGCAAGATCCGGGATGGTAACCTCGCCTTGATGCCGCTGTCGCTGTACTTCTCCGAGGGCAAAGTGAAGGTAGAGCTCG
CTCTCGCGCGCGGCAAGAAGGCTTACGACAAACGCCAGGACCTGGCCCAGCGCGACGCACAGCGCGAAGTCGTTCGTCAA
CTGGGACGCCGAACAAAGGGGATGATCTGA

Protein sequence :
MAKGSGRAKAAGGKGGSKQIIATNRKARHNYSIIETYEAGVALQGTEVKSLREGQASLADAFATIDDGEVWLRNLYIPEY
QHGSWTNHDPRRNRKLLLHRQQIDRLVGKIRDGNLALMPLSLYFSEGKVKVELALARGKKAYDKRQDLAQRDAQREVVRQ
LGRRTKGMI

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-48 69
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 6e-33 49
smpB NP_230495.1 SsrA-binding protein Not tested VPI-1 Protein 5e-23 45