Gene Information

Name : nrdE (MAP3100c)
Accession : NP_962034.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : ribonucleotide-diphosphate reductase subunit alpha
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0209
EC number : 1.17.4.1
Position : 3447754 - 3449934 bp
Length : 2181 bp
Strand : -
Note : Catalyzes the rate-limiting step in dNTP synthesis

DNA sequence :
TTGGAAGGAACAGACGTGTCACCAACCGTCGCTGCAGAGCCTGTAACCGCCGGCGCTCATGGCTTGCCCGACGAAACGGA
CTACCATGCGCTGAACGCGATGCTGAACCTGTACGACGCGGACGGCAAGATCCAGTTCGACAAGGACGTCCTCGCCGCGC
GCCAGTACTTTCTGCAGCACGTCAACCAGAACACCGTCTTCTTTCACAATCAGGACGAGAAACTCGACTACCTGATCCGC
GAAAACTATTACGAGCGTGAGGTTCTCGACCAGTACTCGCGCAACTTCGTCAAGTCGTTGCTGGACCGCGCCTACGCCAA
GAAGTTCCGCTTCCCGACCTTTCTCGGCGCCTTCAAGTACTACACCTCCTACACGCTGAAGACGTTCGACGGGAAGCGCT
ATCTGGAGCGCTTCGAGGACCGCGTGGTCATGGTGGCGCTCACGCTGGCGGCCGGCGACACCGGGCTGGCCGAGAAGCTG
GTCGACGAGATCATCGAGGGCCGTTTCCAGCCGGCCACGCCGACGTTTTTGAACTCCGGCAAGAAGCAGCGCGGCGAGCC
GGTGAGCTGCTTTCTGCTGCGCATCGAGGACAACATGGAGTCCATCGGGCGTTCGATCAACTCCGCGCTGCAGCTGTCCA
AGCGCGGCGGCGGAGTCGCGTTGCTGCTGACCAACATTCGCGAGCACGGCGCGCCGATCAAGAACATCGAGAACCAGTCC
TCGGGCGTCATCCCCATCATGAAGCTGCTGGAGGACTCGTTCTCCTACGCCAATCAGCTCGGGGCGCGCCAGGGGGCCGG
CGCGGTGTACCTGCACGCCCATCACCCCGACATCTACCGCTTCCTGGACACCAAGCGGGAGAACGCCGACGAGAAGATCC
GGATCAAGACGCTGAGCCTGGGCGTGGTGATCCCCGACATCACCTTCGAGCTGGCCAAGAAGAACGAGGACATGTACCTG
TTCTCGCCGTACGACGTGGAACGCGTCTACGGGCTGCCGTTCGCCGACATCTCGGTGACCGAGAAGTACTACGAGATGGT
CGACGACGCCCGCATCCGCAAGACCAAGATCAAGGCGCGGGAGTTCTTCCAGACGCTGGCCGAGCTGCAGTTCGAGTCGG
GCTACCCGTACATCATGTTCGAGGACACGGTGAACCGGGCCAATCCCATCGACGGCAAGATCACCCACTCCAACCTGTGC
TCGGAGATCCTGCAGGTCTCCACGCCGTCGTTGTTCAACGACGACCTGTCGTATGCCAAAGTGGGCAAGGACATTTCGTG
CAACCTGGGTTCGCTGAACATCGCCAAGACGATGGACTCGCCCGACTTCGCCCAGACCATCGAGGTGGCCATCCGGGCGC
TGACCGCCGTTAGCGACCAGACGCACATCACCTCGGTGCCCTCAATCGAGCAGGGCAACAACGATTCTCACGCGATCGGG
CTCGGGCAGATGAACCTGCACGGGTACCTGGCCCGCGAGGGCATCTTCTACGGCTCCGAAGAGGGCATCGACTTCACCAA
CATCTACTTCTACACGGTGCTCTATCACGCGCTGCGCGCGTCGAACCGCATCGCGATCGAACGCGGCACGCACTTCAAGG
GTTTCGAGCGCTCCAAGTACGCGTCGGGGGAGTTCTTCGACAAGTACACCGAGCAGGTGTGGGAGCCGGCGACCGAGAAG
GTGCGCCAACTCTTCGCCGATGCCGGCATCCGCATCCCCACCCAGGACGACTGGAAGCGGCTGAAGGAGTCGGTGCAGGC
GCACGGCATCTACAACCAGAACCTGCAGGCGGTGCCGCCGACCGGGTCGATCTCCTACATCAACCACTCGACGAGCTCGA
TCCACCCGATCGTGTCGAAGGTCGAGATCCGCAAGGAGGGCAAGATCGGGCGGGTCTACTACCCGGCGCCCTACATGACC
AACGACAACCTGGAGTACTACCAGGACGCCTACGAGATCGGTTACGAGAAGATCATCGACACCTACGCCGCGGCCACCCA
GCACGTCGACCAGGGGCTGAGCCTGACGCTGTTCTTCAAGGACACCGCCACCACCCGCGACGTCAACAAGGCGCAGATCT
ACGCCTGGCGCAAGGGCATCAAGACGCTCTACTACATCCGGTTGCGCCAGATGGCGCTGGAGGGAACCGAGGTCGAGGGC
TGCGTGTCCTGCATGCTGTGA

Protein sequence :
MEGTDVSPTVAAEPVTAGAHGLPDETDYHALNAMLNLYDADGKIQFDKDVLAARQYFLQHVNQNTVFFHNQDEKLDYLIR
ENYYEREVLDQYSRNFVKSLLDRAYAKKFRFPTFLGAFKYYTSYTLKTFDGKRYLERFEDRVVMVALTLAAGDTGLAEKL
VDEIIEGRFQPATPTFLNSGKKQRGEPVSCFLLRIEDNMESIGRSINSALQLSKRGGGVALLLTNIREHGAPIKNIENQS
SGVIPIMKLLEDSFSYANQLGARQGAGAVYLHAHHPDIYRFLDTKRENADEKIRIKTLSLGVVIPDITFELAKKNEDMYL
FSPYDVERVYGLPFADISVTEKYYEMVDDARIRKTKIKAREFFQTLAELQFESGYPYIMFEDTVNRANPIDGKITHSNLC
SEILQVSTPSLFNDDLSYAKVGKDISCNLGSLNIAKTMDSPDFAQTIEVAIRALTAVSDQTHITSVPSIEQGNNDSHAIG
LGQMNLHGYLAREGIFYGSEEGIDFTNIYFYTVLYHALRASNRIAIERGTHFKGFERSKYASGEFFDKYTEQVWEPATEK
VRQLFADAGIRIPTQDDWKRLKESVQAHGIYNQNLQAVPPTGSISYINHSTSSIHPIVSKVEIRKEGKIGRVYYPAPYMT
NDNLEYYQDAYEIGYEKIIDTYAAATQHVDQGLSLTLFFKDTATTRDVNKAQIYAWRKGIKTLYYIRLRQMALEGTEVEG
CVSCML

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cur_1481 YP_001800875.1 ribonucleotide-diphosphate reductase subunit alpha Not tested Not named Protein 0.0 79