Gene Information

Name : rph (MAP2422c)
Accession : NP_961356.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : ribonuclease PH
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0689
EC number : 2.7.7.56
Position : 2719336 - 2720115 bp
Length : 780 bp
Strand : -
Note : RNase PH; tRNA nucleotidyltransferase; forms hexamers in Bacillus subtilis; phosphoroltic 3'-5' exoribonuclease; involved in maturation of tRNA precursors and removes terminal nucleotides near CCA acceptor arms of mature tRNAs

DNA sequence :
GTGACGCGACGAGAAGACGGCCGCCTGGACGACGAGCTTCGCCCGCTGGTGATCACCCGCGGGTTCACCGAACACCCCGC
CGGTTCGGTGCTGATCGAATTCGGCCACACCAAGGTGATGTGCACGGCCAGCGTCACCGAGGGCGTGCCGCGCTGGCGCA
AGGGCTCGGGCCTGGGCTGGCTGACCGCCGAGTACGCGATGTTGCCGTCGGCGACGCACACCCGTTCGGACCGCGAATCG
GTCAAGGGCCGGCTGTCCGGGCGCACCCAGGAGATCAGCCGGCTCATCGGTCGGTCGCTGCGGGCCTGCATCGACCTGGC
GGCGCTGGGGGAGAACACGATCGCCGTCGACTGCGACGTGCTGCAGGCCGACGGCGGCACCCGCACCGCGGCAATCACCG
GCGCCTTCGTGGCGCTGGCCGACGCCGTCACCTACCTGTCGGCGGCGGGGAAACTGTCCGATCCGCGGCCGTTGTCGTGT
GCCATCGCGGCGGTCAGCGTCGGCGTGGTCGACGGCCGGATCCGGGTGGACCTGCCCTACGAGGAGGACGCCCGTGCCGA
GGTCGACATGAACGTCGTCGCCACCGACACCGGCACGCTGGTGGAGGTGCAGGGCACCGGCGAGGGGGCGACCTTCCCGC
GTTCGACCCTGGACAAACTGCTCGACGCGGCGCTGGCCGCCTGCGACAAGCTGTTCGCCGCCCAGCGCGAGGCGCTCAAG
CTGCCCTACCCGGGGGTGTTGCCCGAGGGGCCGCCGCCGCCGAAGGCGTTCGGCAGCTGA

Protein sequence :
MTRREDGRLDDELRPLVITRGFTEHPAGSVLIEFGHTKVMCTASVTEGVPRWRKGSGLGWLTAEYAMLPSATHTRSDRES
VKGRLSGRTQEISRLIGRSLRACIDLAALGENTIAVDCDVLQADGGTRTAAITGAFVALADAVTYLSAAGKLSDPRPLSC
AIAAVSVGVVDGRIRVDLPYEEDARAEVDMNVVATDTGTLVEVQGTGEGATFPRSTLDKLLDAALAACDKLFAAQREALK
LPYPGVLPEGPPPPKAFGS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
rph YP_001800860.1 ribonuclease PH Not tested Not named Protein 7e-62 69