Gene Information

Name : guaB1 (MAP1556c)
Accession : NP_960490.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : inosine 5-monophosphate dehydrogenase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0516
EC number : 1.1.1.205
Position : 1709531 - 1710967 bp
Length : 1437 bp
Strand : -
Note : catalyzes the synthesis of xanthosine monophosphate by the NAD+ dependent oxidation of inosine monophosphate

DNA sequence :
ATGAGGTTTCTCGACGGGCATCGACCCGGATACGACCTGACCTACAACGACGTCTTCATCATGCCGAACCGCTCGGAGGT
GCCGTCGCGCTTCGACGTCGACCTGTCCACCGGCGACGGCTCGGGTACCACGATCCCCGTCGTCGTCGCCAACATGACCG
CGGTGGCCGGGCGGCGGATGGCCGAGACGGTGGCCCGGCGCGGCGGCCTGGTGATCCTGCCGCAGGACCTGCCGATCACC
GCGGTGCAGCAGACGGTGCAGTTCGTCAAGAGCCGCGACCTGGTGCTCGACACTCCGGTGCTGCTCGAGCCCGACGACTC
GGTGTCCGACGCGATGGCGCTGATCCACAAGCGTGCGCACGGCGTGGCGGTGGTGGCCTTCGAGGGCCGCCCGCTGGGAC
TGCTGAGCGAATCGTCGTGCCTGGGCGTGGACCGCTTCACCCGGGTGCGCGACGTCGCGATGACCGACTTCGTGGTGGCC
CCGGTGGGCACCGAGCCGCGCAAGATCTTCGACCTGCTCGAGCAGGCGCCCATCGGCGTCGCGGTCGTCACCAACACCGA
CGGCACGCTGGCCGGCGTGCTGACCCGCACCGGAGCCGTGCGCGCCGGCCTGTACACCCCGGCCGTCGATGCGCAGGGCC
GGTTGCGGGTGGGCGCGGCGATCGGCATCAACGGCGACGTGGGGGCCAAGGCGCGGTCACTGGTCGAGGCCGGAATCGAC
CTGCTGGTGATCGACACGGCGCACGGGCATCAGGTCAAGACGCTGGAGGCGATCCGGACCGTCGCCTCGCTCGAGCTGGG
GGTGCCGCTGGTGGCGGGCAACGTGGTTTCGGCCGACGGCACCCGCGACCTGCTGGGCGCCGGGGCGAACATCGTCAAGG
TGGGCGTGGGCCCGGGGGCGATGTGCACCACCCGGATGATGACCGGCGTGGGCCGCCCGCAGTTCTCCGCTGTTGTCGAA
TGTGCTTCGGCGGCAAGGGAACTGGGTGGACATGTATGGGCCGACGGCGGCATCCGGCACCCGCGTGACGTGGCGCTGGC
GCTGGCCGCCGGGGCGTCGAACGTGATGATCGGATCGTGGTTCGCCGGCACCTACGAGTCGCCCGGCGACCTGATGCGCG
ACCGCGAGGACCAGCCCTACAAGGAGAGCTACGGCATGGCGTCCAAGCGGGCGGTGGTCGCCCGCAGCGGCGCCGAGACG
GCCTTCGACCGGGCCCGCAAATCGCTGTTCGAGGAAGGCATTTCGACGTCGCGGATGGGTCTCGACCCGGCCCGCGGCGG
CGTCGAGGATCTGATCGACCACATCACCTCGGGCGTGCGCAGCACCTGCACCTACGTCGGGGCCGCCACCCTGGCGCAGC
TGTACGAACGGGTCGTGGTCGGGGTGCAGTCGACCGCGGGCTTCGCCGAGGGGCATCCGCTTCCGCTGGGCTGGTGA

Protein sequence :
MRFLDGHRPGYDLTYNDVFIMPNRSEVPSRFDVDLSTGDGSGTTIPVVVANMTAVAGRRMAETVARRGGLVILPQDLPIT
AVQQTVQFVKSRDLVLDTPVLLEPDDSVSDAMALIHKRAHGVAVVAFEGRPLGLLSESSCLGVDRFTRVRDVAMTDFVVA
PVGTEPRKIFDLLEQAPIGVAVVTNTDGTLAGVLTRTGAVRAGLYTPAVDAQGRLRVGAAIGINGDVGAKARSLVEAGID
LLVIDTAHGHQVKTLEAIRTVASLELGVPLVAGNVVSADGTRDLLGAGANIVKVGVGPGAMCTTRMMTGVGRPQFSAVVE
CASAARELGGHVWADGGIRHPRDVALALAAGASNVMIGSWFAGTYESPGDLMRDREDQPYKESYGMASKRAVVARSGAET
AFDRARKSLFEEGISTSRMGLDPARGGVEDLIDHITSGVRSTCTYVGAATLAQLYERVVVGVQSTAGFAEGHPLPLGW

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
cpfrc_01479 YP_003783879.1 hypothetical protein Not tested PiCp 5 Protein 2e-136 59
Cp1002_1469 YP_005681736.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 7e-137 59
CpC231_1472 YP_005683835.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-136 59
CpI19_1479 YP_005685921.1 Inosine 5-monophosphate dehydrogenase Not tested PiCp 5 Protein 2e-136 59