Gene Information

Name : tkt (MAP1178c)
Accession : NP_960112.1
Strain : Mycobacterium avium K-10
Genome accession: NC_002944
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 1236763 - 1238862 bp
Length : 2100 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
GTGACGACACTTGAAGAGATCTCTGCGCTGACCCAACCGCACCTTCCCGACGACTGGTCCGAGCTGGACTCGGCCGCCGT
CGACACCATTCGGGTGCTGGCCGCCGACGCGGTGCAAAAGGTGGGCAACGGACATCCCGGGACGGCGATGAGCCTGGCTC
CCCTGGCCTACACGCTGTTTCAGCGGGTGATGCGGCACGACCCCAGCGACACCCACTGGCTGGGCCGGGACCGGTTCGTG
CTGTCGGCCGGGCACAGCAGCCTGACGCTGTACCTGCAGCTGTACCTGGGTGGCTTCGGTCTGGAGCTGTCCGACATCGA
GTCGCTGCGCACCTGGGGCTCCAAGACGCCCGGGCACCCGGAGTTCCGGCACACCAAGGGTGTGGAGATCACCACCGGCC
CGCTGGGCCAGGGCCTGGCCTCCGCGGTGGGCATGGCGATGGCCTCCCGCTACGAGCGCGGGCTGTTCGACCCGGACGCC
GCCGCCGGCACCAGCCCGTTCGACCACTTCATCTACGTGATCGCCTCCGACGGCGACATCGAGGAGGGCGTCACGTCGGA
GGCCTCGTCGCTGGCGGCCGTGCAGCAACTGGGCAACCTGATCGTGTTCTACGACCACAACCAGATCTCCATCGAGGACG
ACACCAACATCGCCCTGTGCGAGGACACCGCCGCCCGCTACGAGGCCTACGGCTGGCACGTGCAGCGCGTCGAGGGTGGC
GAGAACGTCGTCGCCATCGAGGAGGCCATCGCCGCGGCCAAGGCCGTCACCGACCGGCCGTCGTTCATCGAGCTGCGCAC
GATCATCGGCTATCCGGCGCCCAACGCGATGAACACCGGCAAGGCGCACGGCGCGGCGCTGGGCGAGGAGGAGGTGGCCG
CGGTCAAGAAGATCCTCGGCTTCGACCCGGACAAAACGTTCCAGGTGCGCGACGAGGTGATCGCCCACACCCGCAAGCTG
GTCGACCGCGGCCGGGAGGCACACCAGAAGTGGCAGACCGATTTCGACGCCTGGGCGCAGCGCGAGCCCGAGCGCAAGGC
GCTGCTGGAGCGGTTGACGGCCGAGAAGCTGCCCGACGGGTGGGACGCCGACCTGCCGCACTGGGAGGCGGGTTCCGACG
CGATCGCCACCCGCAAGGCCTCCGGCGCGGTGCTCAACGCCGTGGCGCCGAAACTGCCCGAGCTGTGGGGCGGCTCGGCC
GACCTGGCCGAGAGCAACCTCACCACCATCAACAACGCGGATTCCTTTGGGCCCCCGTCGATTTCCACCAAGGAGTTCAC
CGCCTCCTGGTATGGCCGGGTGCTGCATTTCGGTGTCCGCGAACACGCCATGGGGGCGATCCTGTCCGGCATCGTGCTGC
ACGGCCCGACCCGCGCCTACGGCGGCACCTTCCTGCAGTTCTCGGACTACATGCGTCCGGCGGTGCGGCTGGCCTCGCTG
ATGGACATCGACACCATCTACGTGTGGACGCACGATTCCATCGGGCTGGGTGAGGACGGGCCGACGCACCAGCCGATCGA
GCACCTGGCGGCGTTGCGCGCCATCCCCAAGCTGTCGGTGGTGCGCCCGGCCGACGCCAACGAGACCGCCTACGCCTGGC
GCACCATCCTGGCCCGCGGCAACGGCAGCGGCCCGGTCGGATTGGTCCTGACCCGCCAGGGCCTGCCGGTGCTCGAGGGC
ACCGACGCCGACGGTGTCGCCCGCGGCGGCTACATCCTGGGCTCGGACGGCGAGGAGGCCGGCCAGGAGCCCGACGTCAT
CCTGATCGCCACCGGCTCGGAGGTACAGCTGGCCGTCGAGGCGCAGAAGTTGTTGGCGGACAAGGACATTGTGGCGCGGG
TGGTGTCCATGCCGTGCGTGGAATGGTTCGAGTCCCAGCCCGACGACTACCGCGACAGTGTGCTGCCGCCGTCGGTGTCG
GCCCGGGTGGCCGTCGAGGCCGGGGTGGCGCAGAGCTGGCACAAGCTGGTCGGCGACACCGGGAAGATCATCTCGATCGA
GCACTACGGCGAATCCGCCGACTACAAAACGTTGTTCCGTGAATTCGGATTCACCGCCGAAGCCGTCGCTGCCGCCGCGG
AAGAAGTCGTGGACAACTGA

Protein sequence :
MTTLEEISALTQPHLPDDWSELDSAAVDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRVMRHDPSDTHWLGRDRFV
LSAGHSSLTLYLQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTKGVEITTGPLGQGLASAVGMAMASRYERGLFDPDA
AAGTSPFDHFIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDHNQISIEDDTNIALCEDTAARYEAYGWHVQRVEGG
ENVVAIEEAIAAAKAVTDRPSFIELRTIIGYPAPNAMNTGKAHGAALGEEEVAAVKKILGFDPDKTFQVRDEVIAHTRKL
VDRGREAHQKWQTDFDAWAQREPERKALLERLTAEKLPDGWDADLPHWEAGSDAIATRKASGAVLNAVAPKLPELWGGSA
DLAESNLTTINNADSFGPPSISTKEFTASWYGRVLHFGVREHAMGAILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLASL
MDIDTIYVWTHDSIGLGEDGPTHQPIEHLAALRAIPKLSVVRPADANETAYAWRTILARGNGSGPVGLVLTRQGLPVLEG
TDADGVARGGYILGSDGEEAGQEPDVILIATGSEVQLAVEAQKLLADKDIVARVVSMPCVEWFESQPDDYRDSVLPPSVS
ARVAVEAGVAQSWHKLVGDTGKIISIEHYGESADYKTLFREFGFTAEAVAAAAEEVVDN

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 1e-107 44
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 2e-104 43