Gene Information

Name : metC (lpg0890)
Accession : YP_094924.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Resistance
Product : cystathionine beta-lyase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0626
EC number : 4.4.1.8
Position : 962856 - 964007 bp
Length : 1152 bp
Strand : -
Note : -

DNA sequence : 
ATGAATAAGACTCATTTCGATACACGTGCAATTCATGCTGGGCAAGAACCATGTAAAAGTACAGGGGCCGTGATGACCCC
TATTTATGCTACCTCCACCTATAAACAAATTGCTCCTGGCGAACATCTTGGCTATGAATACTCACGCACCCAGAACCCCA
CCAGAAAGGCCTATGAGGATTGCATAGCAAGTCTTGAATCAGGCCAAAAAGGATTTGCGTTTGCTTCAGGTATGGCTGCC
ATCAATACAGTTATTGATTTATTAGGTTCCGGAGATCACGTCGTTGCCATGGATGATCTTTATGGAGGGACTTTCCGGCT
TTTTGATAAAGTAAAAACCCGAACTTCTAATTTATCCTTTTCTTTTATTGATATGTCAGTACCCGAGAATATTGAAGCTG
CAATAACTCCGAAGACAAAATTACTATGGTTGGAAACCCCTTCCAATCCCATGCTAAAGCTAGCTAATTTACGAAAAATC
GCTGCTATTGCAAAAAAATATAATTTGATTACAGTTGCCGATAACACCTTTGCAACTCCCTGGATTCAACGCCCTCTTGA
ACTCGGATTTGACATTGTACTTCATTCAGCAACCAAATATCTGAACGGACATTCTGATGTAGTCAGTGGTGTCGTTGTGG
TCGGTGACAATTCAGTGTTGTCTGATAAAATTGCTTTTTTGCAAAATTCATGCGGCGCTGTAGCTGGCCCTTTCGACAGT
TTCCTGGTTCTGAGAAGCTTAAAAACATTATCCGTTCGTATGCAAAGGCACTGTGAAAACGCTAACCATCTGGCTAACTG
GCTTAGCAGCCACCCCAAGATTGAAAAAGTCATTTATCCCGGATTAAAAAGTCATCCGCAATATTCTCTTGCCAAGGAAC
AAATGAACAATTTCGGTGGTATGATATCTTTGGTACTTAAAGGTAGTCTTGAAGATGCCAAACGATTTTTAGCTCGCTGC
GAATTATTTACTTTGGCTGAAAGCCTGGGGGGTGTAGAAAGTTTAATTGAGCATCCTGCAATTATGACCCATGCCTCTAT
TCCAGTCGAACAACGCAAAGCCCTGGGCATAGAAGATGGTTTCATAAGATTATCAGTTGGTATTGAACACATTGATGATC
TGCGTGCCGATCTGGAGCATGCTTTAGGTTAA

Protein sequence : 
MNKTHFDTRAIHAGQEPCKSTGAVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIASLESGQKGFAFASGMAA
INTVIDLLGSGDHVVAMDDLYGGTFRLFDKVKTRTSNLSFSFIDMSVPENIEAAITPKTKLLWLETPSNPMLKLANLRKI
AAIAKKYNLITVADNTFATPWIQRPLELGFDIVLHSATKYLNGHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDS
FLVLRSLKTLSVRMQRHCENANHLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMISLVLKGSLEDAKRFLARC
ELFTLAESLGGVESLIEHPAIMTHASIPVEQRKALGIEDGFIRLSVGIEHIDDLRADLEHALG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAS0418 YP_042545.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 4e-75 47
SAR0460 YP_039909.1 Cys/Met metabolism PLP-dependent enzyme Not tested vSa¥á Protein 5e-74 47
metB YP_281510.1 cystathionine beta-lyase Not tested Not named Protein 6e-55 43

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
metC YP_094924.1 cystathionine beta-lyase BAC0207 Protein 5e-67 45