Gene Information

Name : serS (lpg0513)
Accession : YP_094557.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 553352 - 554632 bp
Length : 1281 bp
Strand : +
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGTTAGATAATCAATTACTTCGAGAGAATCCTCAATATGTAGCAACCCAATTGCTGAAACGAGGATTTCAATTTGATGC
GGTCACTTTCAGTCAGTTGGAAGAAAAGCGTAAGGCTTTGCAAGTAAGTACGCAATCATTACAGAACGAACGAAATTTGC
GTTCGAAAGCCATCGGTGAAGCTAAATCTCGAGGTGAAAACATAGGGCCTATGCGCGAAGAAGTGAATAAACTTGGCGCT
ATACTGGAGCAGCAAAAGACTGAACTGGACGAGGTTCTTAAACAAATTGAGGTAATTAGCCTATCATTACCTAATATTCC
TCATGAATCAGTACCTGTTGGTAAAGATGAATTGGATAATCAGGAAATCAGAAAATGGGGCGACGTACCTGCTTTTTCTT
TCCCTGTAAAGTCACATGATGAATTGGGTGAAGCGCTAGGGCAAATGGATTTTGCGCTTGCAGCTAAAATTACGGGCAGC
CGTTTTGTCGTCATGAAAGGGCATCTGGCCCGATTACATAGGGCTTTAATTCAATTTATGCTGGATATACATATTCAGCA
ACATGGTTACCAGGAAATATATGTACCTTATATTGTTAATGCGGATAGCTTACTAGGGACTGGGCAGTTACCAAAGTTTG
AGGCTGATTTATTTAAATTAACAGGAGATAATGGGTACTACTTGACGTCTACTTCAGAAATTCCAGTGACCAATACAGTA
AGGGAAATGATATTGTCTGCTGAGCAATTACCTATTCGTTATGTTTGCCATTCCCCATGTTTTCGTAGTGAGGCGGGTTC
TTATGGTAAAGACACAAAGGGAATGATTAGACAGCATCAATTTGAGAAAGTTGAACTGGTCTGGATTACCAAACCGGAAG
ATTCTTATAATGCTTTAGAGCAACTTACTCAGCATGCTGAAATTATTTTACAGCGTTTGAACTTGCCTTACCGAGTGGTT
GCTTTGTGTACCGGGGATATAGGTGCCGGTTCAGCCAAAACCTATGATCTTGAGGTTTGGTTGCCTAGCCAGAATACTTA
TCGAGAAATATCCTCTTGTTCCAATATGGAGGCATTTCAGGCACGCCGAATGAAAGCGCGTTTCCGCAATCCGGATACTA
ATGAGATTCAATTAGTCCACACTCTAAATGGATCAGGTTTAGCTGTTGGAAGAACTTTAGTTGCCATTATGGAGAATTAT
CAAGATGAGCATGGAAACATTCATATACCGGATGCTTTGAAGCCTTATTTAGGTGGTATTGATATCATCTCTGTGAAATA
G

Protein sequence :
MLDNQLLRENPQYVATQLLKRGFQFDAVTFSQLEEKRKALQVSTQSLQNERNLRSKAIGEAKSRGENIGPMREEVNKLGA
ILEQQKTELDEVLKQIEVISLSLPNIPHESVPVGKDELDNQEIRKWGDVPAFSFPVKSHDELGEALGQMDFALAAKITGS
RFVVMKGHLARLHRALIQFMLDIHIQQHGYQEIYVPYIVNADSLLGTGQLPKFEADLFKLTGDNGYYLTSTSEIPVTNTV
REMILSAEQLPIRYVCHSPCFRSEAGSYGKDTKGMIRQHQFEKVELVWITKPEDSYNALEQLTQHAEIILQRLNLPYRVV
ALCTGDIGAGSAKTYDLEVWLPSQNTYREISSCSNMEAFQARRMKARFRNPDTNEIQLVHTLNGSGLAVGRTLVAIMENY
QDEHGNIHIPDALKPYLGGIDIISVK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 6e-100 51