Gene Information

Name : purA (lpg0486)
Accession : YP_094530.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Unknown
Product : adenylosuccinate synthetase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0104
EC number : 6.3.4.4
Position : 525922 - 527217 bp
Length : 1296 bp
Strand : +
Note : catalyzes the formation of N6-(1,2,-dicarboxyethyl)-AMP from L-aspartate, inosine monophosphate and GTP in AMP biosynthesis

DNA sequence :
ATGGGTAAGAATGTTGTTGTTTTGGGTACACAATGGGGAGATGAAGGCAAAGGCAAAATTGTTGATTTGCTGACACAAGA
TGCTCAAGTGGTTGTCCGTTATCAAGGGGGCCATAATGCAGGCCATACATTAAAAATCAATGGAGTAAAAACAGTACTTC
GTTTAATTCCATCCGGGATGCTTCGCCCTAACGTAACCTGCTATATTGCAAATGGTGTGGTTTTATCACCTCAGGCATTA
CTTAGTGAAATTAAGGAGCTTGAGGGTAATGGCATCAATGTGAGGGAGCGATTACGCATTAGCCTGGCTTGCCCCCTGAT
TCTCCCTTACCACATTGCTTTGGATAAGGCTCGTGAGACACATATGGGCAAGTCTGCAATTGGAACAACAGGTCGTGGTA
TAGGTCCTGCTTATGAGGATAAAGTGGCTCGGCGCGCTTTAAGAGTAGGTGATTTATTTCATAGAGACCGATTTGCCAAT
AAATTAACAGAATTATTGGATTATCATAATTTTGTATTAACACAATATTTCAAACAACCAGCTGTTGATTTGGAATCCCT
ATTGGGTGAGTCATTACAATGGGCTGAAGAATTAAGACCAATGGTTTGCGATGTTTCTGCATGTTTGCATGAACATAGAA
AACAAGGTGAAAATATTTTATTCGAAGGGGCGCAAGGTGTTTATTTAGATATTGATCATGGAACATACCCCTACGTAACT
TCTTCAAATACCTGTGTGGGATCTGTAATTAATGGTGCGGGATTTGGTCCTCGCTATATTGATTACGTGTTAGGCATTAC
AAAAGCTTACACAACTCGAGTTGGCGGTGGCCCATTCCCCACTGAATTACTTGATGACGTTGGAAAACGCATTGCGGAAC
GAGGACAGGAATTCGGCGCAGTAACTGGTAGACCCAGACGTTGTGGGTGGTTTGACGCTGTTTTATTAAAACGCTCGATT
GAGTTAAATAGTATTTCAGGACTCTGTGTTACCAAATTGGATGTTCTCGATGGCTTAGAGGTATTACGGATTGCTGTGGC
TTATAAAGACAGGGATGGCAATATATTATCTCGACCTCCTCTGGCAGCTGATGATTTCAACGATTTGTTACCAGTCTATG
AGGAGCTTCCTGGTTGGCAGGAATCTACTGCTGATGTGACTGTGATGAGTGACTTACCCGCCAATGCAAGGGCTTATCTA
AAGCGAATTGAAGAGATATTAGGGATTCCTATTGATATGCTATCAACAGGACCTGAAAGGGATTCAACAATTACTTTACG
AGGTCCTTTTCTTTGA

Protein sequence :
MGKNVVVLGTQWGDEGKGKIVDLLTQDAQVVVRYQGGHNAGHTLKINGVKTVLRLIPSGMLRPNVTCYIANGVVLSPQAL
LSEIKELEGNGINVRERLRISLACPLILPYHIALDKARETHMGKSAIGTTGRGIGPAYEDKVARRALRVGDLFHRDRFAN
KLTELLDYHNFVLTQYFKQPAVDLESLLGESLQWAEELRPMVCDVSACLHEHRKQGENILFEGAQGVYLDIDHGTYPYVT
SSNTCVGSVINGAGFGPRYIDYVLGITKAYTTRVGGGPFPTELLDDVGKRIAERGQEFGAVTGRPRRCGWFDAVLLKRSI
ELNSISGLCVTKLDVLDGLEVLRIAVAYKDRDGNILSRPPLAADDFNDLLPVYEELPGWQESTADVTVMSDLPANARAYL
KRIEEILGIPIDMLSTGPERDSTITLRGPFL

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
purA YP_281500.1 adenylosuccinate synthetase Not tested Not named Protein 2e-92 48