Gene Information

Name : gbsA (lpg0238)
Accession : YP_094292.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Virulence
Product : glycine betaine aldehyde dehydrogenase
Function : -
COG functional category : C : Energy production and conversion
COG ID : COG1012
EC number : 1.2.1.8
Position : 281131 - 282597 bp
Length : 1467 bp
Strand : +
Note : -

DNA sequence : 
ATGGAAATTTACAAAATGTACATTGATGGGAAATTTACTTTAGCCAAAAGTGGGGCTACACGTGACATTTTTGATCCGGC
TAATGGGGATTTGATTGCAAAAGTGCCAGAAAGTGCTAAAGAAGATGCCATACTTGCTATCAAAGCAGCGAGAAAAGCCT
TCGATGAAGGAGAGTGGAGAAAATCACTGGCGCTTGATCGAGGCAAATTGTTATTCAAGCTTGCTGATTTGATTCGAGCC
AATGCTAAAATGTTGGCAGAACTGGAAACTCGAAATTGCGGAAAGCCGTTACTCGAAGCGGAGTTTGATGTCACTGATGC
TGCCAATTGCTTTGAATTTTACGGTGGGCTTGCGACTAAAATTCATGGTGAAACGATGTCGGTTCCAGCGAATTCATTTA
GTTACGTAGTACGTGAACCCATAGGCGTGTGTGGTCAAATCATTCCATGGAATTTTCCACTGCTTATGGCGGCCTGGAAA
CTTGCCCCCGCACTTGCCGCAGGCAATACCGTGGTATTAAAACCATCAGAATTGACCCCGATAACGGCACTTGAGTTATT
CAAGTTGATTGATGAATGCGGATTTCCAGCGGGCGTGGTTAACCTCATTACTGGGCCGGGTATAGGAGTTGGAGAGGAGT
TGGCAAGTAATGCTATGGTGGATAAGGTTGCTTTCACCGGAGGATCGGCAACAGGCAGAAAAATCATGCAGGCGGCTACT
GGCAATTTGAAAAAAATCTCGTTAGAGCTTGGCGGAAAAAATCCAAATATTGTCTTTGCAGACTCTGACCTTGAAATGGC
AATCGACGGTGCCCTTTTTGGTGCTTTTGCAAATCAAGGGGAAGTCTGTTCTGCGGGTTCCCGCTTGCTAGTGGAGCGCT
CTATTCACAAAAAAATAGTAGAGGGAATGTTGAAAAAAATTCCAAATATCAAGCTTGGCCATGGTTTGGACGCCGGGGTA
AAAATGGGGCCTTTGGTTTCAAGTGCACATCGTGAAAAAGTGGAAAGCTATGTCAAGCTTGGAATGGAAGAAGGAGCCAA
ATTACTTTGCGGCGGTAAACGCCCGACAGGCAATGAATTTGCAAAGGGACATTTTTTCGAGCCAACCATTTTTGATGAAG
TGAAATCCACGATGCGCATTGCTCGTGAAGAAATTTTTGGTCCAGTACTCGTAGTGATACCTTTTGACACTGAAGAAGAG
GCCATTCGCATTGCGAACGATACTGATTATGGTTTATCTGGGGCTGTATGGACGAAGAGCGTTACTCGGGCCCATCGAGT
CACATCTCAAATCCGTGCCGGGATTCTTTGGGTGAATCATTACCATCCAACCTATAATGAAATGCCTTGGGGCGGATACA
AACAAAGCGGAGCGGGTCGTGAGTTAGGTTTGTATGGCATTGAGAGTTACCTTGAGGTCAAGCAAGTGAATATTAATCTG
GATGAAACACCAATTGGTTGGTACTAA

Protein sequence : 
MEIYKMYIDGKFTLAKSGATRDIFDPANGDLIAKVPESAKEDAILAIKAARKAFDEGEWRKSLALDRGKLLFKLADLIRA
NAKMLAELETRNCGKPLLEAEFDVTDAANCFEFYGGLATKIHGETMSVPANSFSYVVREPIGVCGQIIPWNFPLLMAAWK
LAPALAAGNTVVLKPSELTPITALELFKLIDECGFPAGVVNLITGPGIGVGEELASNAMVDKVAFTGGSATGRKIMQAAT
GNLKKISLELGGKNPNIVFADSDLEMAIDGALFGAFANQGEVCSAGSRLLVERSIHKKIVEGMLKKIPNIKLGHGLDAGV
KMGPLVSSAHREKVESYVKLGMEEGAKLLCGGKRPTGNEFAKGHFFEPTIFDEVKSTMRIAREEIFGPVLVVIPFDTEEE
AIRIANDTDYGLSGAVWTKSVTRAHRVTSQIRAGILWVNHYHPTYNEMPWGGYKQSGAGRELGLYGIESYLEVKQVNINL
DETPIGWY

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
ORF SG19 AAN62241.1 putative aldehyde dehydrogenase Not tested PAGI-3(SG) Protein 5e-77 44
VC0819 NP_230467.2 aldehyde dehydrogenase Not tested VPI-1 Protein 1e-71 41
aldA AAC12273.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41
aldA AAK20747.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41
aldA AAK20776.1 aldehyde dehydrogenase Virulence VPI Protein 1e-73 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
gbsA YP_094292.1 glycine betaine aldehyde dehydrogenase VFG0082 Protein 5e-72 41