Gene Information

Name : fliP (lpg1789)
Accession : YP_095815.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Virulence
Product : flagellar biosynthesis protein FliP
Function : -
COG functional category : N : Cell motility
COG ID : COG1338
EC number : -
Position : 1996806 - 1997555 bp
Length : 750 bp
Strand : -
Note : FliP, with proteins FliQ and FliR, forms the core of the central channel in the flagella export apparatus

DNA sequence : 
ATGAAAATTAAAAGTTGGTTACTGATTTTGATATTATTTCTTTTATTACCTGTTGCAGGTCACACAGACCCTTTATCCTT
TCCCGTTGTTACAATGCAACCTGGAACTGATGGTTCGCAATCTTATAGTATCAATCTGCAAATTTTAATTTTTATGACTT
TATTGACCGTATTGCCAGGATTGCTGATGGCAATGACGTCATTTACAAGGATAATTATTGTTCTGTCAATTTTACGGCAG
GCAATAGGGATGGCTCAGACGCCTACCAATCAAATATTAATCGGCATTGCTCTATTTATGACTTATTTTGTTATGTCACC
TGTATTCAACAAAATTAATGAAACAGCAATACAGCCCTATATGAATGAAAGGATTGATTTTTCTCTGGCATTATCCAATG
CACAAAAGCCGCTTCGTCAGTTTATGCTAAATCAAACGAGAAAAAATGATTTATCTTTATTTGAAAAATTTGCTCACAAT
GTACCAAAAAGTTTAGATGAGATTCCTATGAGTGTTCTCATTCCGGCTTTCATTACTAGCGAGTTAAAAACCGCATTTCA
GATAGGCTTTATTCTATTTTTACCTTTTTTAATTATTGATCTTGTTGTGTCCAGTGTTTTGATGGCTATGGGGATGATGA
TGCTTTCACCCTTGATTATTTCATTACCTTTTAAAATCATGTTGTTTGTGATGGTTGATGGATGGACTTTGGTTTTGGGT
TCACTTGCTTCAAGTTTTGCTCTTGCCTAG

Protein sequence : 
MKIKSWLLILILFLLLPVAGHTDPLSFPVVTMQPGTDGSQSYSINLQILIFMTLLTVLPGLLMAMTSFTRIIIVLSILRQ
AIGMAQTPTNQILIGIALFMTYFVMSPVFNKINETAIQPYMNERIDFSLALSNAQKPLRQFMLNQTRKNDLSLFEKFAHN
VPKSLDEIPMSVLIPAFITSELKTAFQIGFILFLPFLIIDLVVSSVLMAMGMMMLSPLIISLPFKIMLFVMVDGWTLVLG
SLASSFALA

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
escR AFO66317.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-21 43
escR AFO66400.1 putative LEE-encoded type III secretion system factor Virulence SESS LEE Protein 3e-21 43
hrcR ABA47279.1 HrcR Virulence S-PAI Protein 6e-20 42
hrcR AAT96303.1 HrcR Virulence S-PAI Protein 2e-18 42
hrcR AAT96343.1 HrcR Virulence S-PAI Protein 2e-18 42
hrcR AAT96262.1 HrcR Virulence S-PAI Protein 2e-18 42
hrcR NP_791222.3 type III secretion protein HrcR Virulence Hrp PAI Protein 3e-12 41
hrcR AAP34349.1 HrcR Virulence Hrp PAI Protein 1e-23 41
YPO0270 YP_002345352.1 type III secretion system protein Virulence Not named Protein 1e-22 41
escR CAI43889.1 EscR protein Virulence LEE Protein 1e-21 41
escR AAC31528.1 L0049 Virulence LEE Protein 1e-21 41
ECs4583 NP_312610.1 type III secretion system protein Virulence LEE Protein 4e-21 41
escR ACU09473.1 type III secretion system protein EscR Virulence LEE Protein 1e-21 41
escR YP_003223490.1 T3SS structure protein EscR Virulence LEE Protein 2e-21 41
escR YP_003232138.1 type III secretion system protein Virulence LEE Protein 2e-21 41
escR YP_003236103.1 T3SS structure protein EscR Virulence LEE Protein 2e-21 41
escR AAK26700.1 EscR Virulence LEE Protein 1e-21 41
escR NP_290283.1 type III secretion system protein Virulence LEE Protein 2e-21 41
escR AAL57527.1 EscR Virulence LEE Protein 1e-21 41
escR CAC81847.1 EscR protein Virulence LEE II Protein 1e-21 41

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG2016 Protein 1e-96 100
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG1259 Protein 1e-56 62
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG2338 Protein 4e-50 55
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG2494 Protein 6e-50 54
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG2131 Protein 4e-24 43
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG0044 Protein 1e-21 42
fliP YP_095815.1 flagellar biosynthesis protein FliP VFG0827 Protein 7e-22 41