Gene Information

Name : tktA (lpg0139)
Accession : YP_094193.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Unknown
Product : transketolase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG0021
EC number : 2.2.1.1
Position : 167051 - 169129 bp
Length : 2079 bp
Strand : -
Note : catalyzes the formation of ribose 5-phosphate and xylulose 5-phosphate from sedoheptulose 7-phosphate and glyceraldehyde 3-phosphate; can transfer ketol groups between several groups; in Escherichia coli there are two tkt genes, tktA expressed during expo

DNA sequence :
ATGAATGGTCTTCTTGCCGATTTATGCCTTCTGAGCGACAATAGTGCCTCAGTTAAATGCAAAAGAGTAGGCATGAACAG
TTTTACAGAATTAGCTAATGCAGTACGCATGTTAAGCATCGATGCAGTAAACCAAGCTCAATCAGGCCACCCTGGCATGC
CCTTGGGTATGGCTGATATTGCCACCGTTTTATGGAAAAAATTTCTAAAATTCAACCCCAAAAACCCGCACTGGTTTAAC
AGAGACCGTTTTGTATTATCTAATGGCCATGGTTCCATGCTTCTCTATTCTTTACTGCATTTGACCGGATACAACTTGGA
TATTAGCGAGCTTAAAAACTTCCGCCAATTGCACTCAAAAACACCAGGGCATCCGGAACATGGGCACACTCCTGGTGTCG
AAACAACAACAGGGCCATTAGGTCAGGGTTTAGCCAATTCAGTCGGGATGGCCTTAGCGGAGCGTGTGCTGGCTAGTACC
TTTAACCACGATCACTTTAACCTGGTTGATCATTATACATATACTTTTGCCGGTGATGGTTGCCTGATGGAAGGCATTTC
TCATGAGGCGTGTTCTTTAGCTGGCACTCTTGGTTTGGGAAAGCTCATTGTATTTTATGACGACAATGGGATATCTATTG
ATGGTAAGGTAGAATCCTGGTTTACGGACGATACTACGTCTCGCTTTAAAGCCTACAACTGGCAAGTCATAGGCCCCATC
GATGGCCACGACGCAGATCAAATTGAGCAAGCCATATCAGCAGCACGCGAGAACACGACTCAACCTTCATTAATTATCTG
TAAAACCGTCATAGGACTGGGCTCCTCTGTAGCCGGTAGCGAAAAAGCGCACGGCTCTCCATTGAGTGCCCAAGACATAA
ATAATGTCCGTGAATTTTTTAATTGGAAACATGCTCCCTTTGAAATTCCAGATTCGATATACAAGCAATGGGATCATAGA
GAGCAAGGAGAAAAAGAAGAGCAACAATGGCTGCAGCTCCTGCATGAATACCGGCAACAACATCCATCGGAACACGATGA
GTTTTTGCGTCGTGCCAATGGCGACCTGCCCGATGATTGGCAAGAAATATCGGCTGGATTCCTAAAACAATGCCTGAACA
ATGAGAAAGCCATAGCAACGCGTAAGGCGTCGCAGCAATGCATAGAGTTTTTCGCGCCAATATTACCGGAAATGTTTGGC
GGCTCAGCGGATTTGACTGGTTCCAATAATACCGACTGGTCAGGCAGCAAAGCCATCACGGCCCATAATTTTTCCGGAAA
TTACCTTTATTATGGAGTGAGGGAATTTGCCATGGCAGCCATCATGAATGGACTTGCTGTGCATGGGGGATTCATTCCCT
ACGGCGGAACATTCCTTGTTTTCGCAGATTATGCAAGAAATGCCATCCGTTTAAGCGCTTTAATGAAACAAAGAGTGATA
TACGTATTGACTCATGATTCTATCGGTTTAGGGGAAGATGGCCCGACACACCAACCTATAGAACATATCGCTATGTTAAG
AATGACCCCTGGCATGACGGTCTGGCGCCCTGCTGATTTGATGGAAACCGCTGTTGCATGGCAACAATCGTTAGAACATC
ATAATGGCCCGTCTGCCTTATTACTCTCAAGACAAAATCTGCCCGCTTTAGCCCATGGCACCGATGCGGCTGACTTGATT
AAGAAAGGCGGATATATTATTGCCGATTGTGAAGGGAAACCTGATGCTATCCTGATAGCCACTGGTTCAGAAGTTCAACT
GGCTATAACCGCAGCAGAAAAGGCAAAAGCAAGAGGTCTCCAGGTCAGGGTGGTATCCATGCCCTGTGCTGAGCGATTCC
TTGCCCAGAGTGATGATTACAAAAACCAGGTATTACCTGGTCAGGTTCGCACACGTATTGCGATAGAAGCAGCTAGCAGT
GCCTATTGGCACCAATTTGTTGGCTTTGACGGCGCTGTCATTGGGCTGGATTGTTTTGGGGTATCAGCTCCTGCTACAGA
TGCTTTTAATTACCTTGGAATTACAGTAGAAAAAATTATCAATACTCTAGATACATTAACCAAACAAACAATGGTGTAA

Protein sequence :
MNGLLADLCLLSDNSASVKCKRVGMNSFTELANAVRMLSIDAVNQAQSGHPGMPLGMADIATVLWKKFLKFNPKNPHWFN
RDRFVLSNGHGSMLLYSLLHLTGYNLDISELKNFRQLHSKTPGHPEHGHTPGVETTTGPLGQGLANSVGMALAERVLAST
FNHDHFNLVDHYTYTFAGDGCLMEGISHEACSLAGTLGLGKLIVFYDDNGISIDGKVESWFTDDTTSRFKAYNWQVIGPI
DGHDADQIEQAISAARENTTQPSLIICKTVIGLGSSVAGSEKAHGSPLSAQDINNVREFFNWKHAPFEIPDSIYKQWDHR
EQGEKEEQQWLQLLHEYRQQHPSEHDEFLRRANGDLPDDWQEISAGFLKQCLNNEKAIATRKASQQCIEFFAPILPEMFG
GSADLTGSNNTDWSGSKAITAHNFSGNYLYYGVREFAMAAIMNGLAVHGGFIPYGGTFLVFADYARNAIRLSALMKQRVI
YVLTHDSIGLGEDGPTHQPIEHIAMLRMTPGMTVWRPADLMETAVAWQQSLEHHNGPSALLLSRQNLPALAHGTDAADLI
KKGGYIIADCEGKPDAILIATGSEVQLAITAAEKAKARGLQVRVVSMPCAERFLAQSDDYKNQVLPGQVRTRIAIEAASS
AYWHQFVGFDGAVIGLDCFGVSAPATDAFNYLGITVEKIINTLDTLTKQTMV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
tktA AAO17218.1 TktA Not tested tcd island Protein 0.0 57
APECO1_2641 YP_859417.1 transketolase Not tested Not named Protein 0.0 57