Gene Information

Name : lpg1010 (lpg1010)
Accession : YP_095043.1
Strain : Legionella pneumophila Philadelphia 1
Genome accession: NC_002942
Putative virulence/resistance : Resistance
Product : cadmium efflux ATPase
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG2217
EC number : 3.6.3.3
Position : 1103657 - 1105564 bp
Length : 1908 bp
Strand : +
Note : -

DNA sequence :
ATGGGCTGCTCGACATGCTCTTCACATAAAGAGCCAATGCCAAAGCTGTGGCATAATCCCAAAGTCATTACAGCAACTAT
AGCTGGTTTATTATTAACTATTGGTTTTGTAGGCTCATATTTGACATTACCAAAAATTATCGCTAACGGGTTTTACGTAG
GCGCAGTTTTAATTGGCGGATATTATTTCGCTCGCGAAGCAATAGACGAATTTATCAAAGAATATGAAATCGGTATTGAA
TTCTTGATGTCTCTTGCTGCCATTGTTGCTGGTATCATGGGACAATGGGCGGAAGCAGCAACATTGGTATTTTTGTATTC
TATTTCTGAAGCTGCTGAAGGTTATTCTGGTGAAAGAGCGCGGCATGCTATCCGAGCATTGATGGATCTTGCCCCAAAAA
CAGCATTAATCCGGCGAAATAATACTGAATTTCGAATACCCATAGAAGAAATTCACATTGGAGATGAATTCATTGTTCTT
CCTGGTGAAAGTCTTGCTACAGATGGAGAAGTCATTTCAGGACATTCTAGTGTTAATCAAGCACCTATTACGGGTGAGTC
AATTCCAGTAGAAAAAACTATAGGGAGTAAAGTTTTTTCTGCAACTATAAACGGTGAAGGAACTCTTACTGTTCGTGCAA
CCAAAAAATTTGCTGATAATACATTATCTCGTATCATATTTCTTGTCGAAAAAGCACAAGACAAAAAGGGGCGTAGTCAA
CGTTTTATAGAACGTTTTGGTAACCTATATAGTCCATTTGTCCTTTTGGTGGGAATACTCATAGCTACTTTACCACCTCT
ATTTGGGCAACCTTGGCAAGAGTGGGTGATTCGTGCCACAGTATTTATTGTTGCTGCAGCACCATGTGCCCTAGTGATTT
CTATACCCATTACACTTGTAGCTGCTCTTGGCACAGCAAGTCGAAATGGAATATTACTAAAAGGTGGCTTATATTTGGAG
CAACTAGTGAAGATAAAGGTTATTGCACTAGATAAAACAGGAACATTAACACAAGGTAAACCGAAGGTTACTGATATCAT
TCCATTGAATAACCATACTCGGAACCAAATTTTAAATGCAGCAGCAACTCTTGAATCGCGTTCCCAGCATCCCATGGCCC
AAGCCATTTTGCAACAAGCCAATGAAGAAAATATTCAATATAATCCTGTTGAACAGTTTAAGTCATTAACTGGTTCAGGT
GTACTTGGTTTTATCAATGGGGAAAAATTCTACATAGGCAATCCAAAATTATTTATTGATATGGGCCTATTGATAGAAAC
ATTAACACAGGAAATAAATAAATTACAGGCCGCTGGAAAGACAGTCGTATTATTAGGAACTGATAAGGAAATCCTCGGTT
TAATTGCAATTGCTGATCCTCTAAGACCAACAGCCAGGCAGATGGTGTCTAACTTAAAATCGATGGGTATTGAACGTGTG
GTTATGCTCACAGGAGATAATTTGATAACTGCCTCTTCAATTGGTGAACAGGCGGGTGTTGATGAAGTATTTTCTGATTT
ATCACCAGAAGATAAGACACGAAAAATTGAAGAGTTAGAAAGACGTTATGGTAAGGTAATGATGGTTGGTGATGGAGTAA
ATGATGCTCCAGCACTCGCAGCAGCTCATGTAGGAGTTGCTATGGGAGCTGTCGGAACCGATGTTGCATTAGAAACTGCG
GATGTAGCCTTAATGGGTGATAATTTATTAAAATTACCTTATCTTATCGCATTTAGTCGTCGAACCTGGAATATAATTTT
ACAAAACTTGGGACTTTCTATAATTGTAATTAGCTCTCTTGTTGTCGGTGCAATAACAGGTTATTTCACGTTGCCGATAG
CAGTTTTAGCTCATGAAATCAGTGAGCTTATTGTTATTGCAAGTGGTCTTCGTATGTTAAAGTCTTAG

Protein sequence :
MGCSTCSSHKEPMPKLWHNPKVITATIAGLLLTIGFVGSYLTLPKIIANGFYVGAVLIGGYYFAREAIDEFIKEYEIGIE
FLMSLAAIVAGIMGQWAEAATLVFLYSISEAAEGYSGERARHAIRALMDLAPKTALIRRNNTEFRIPIEEIHIGDEFIVL
PGESLATDGEVISGHSSVNQAPITGESIPVEKTIGSKVFSATINGEGTLTVRATKKFADNTLSRIIFLVEKAQDKKGRSQ
RFIERFGNLYSPFVLLVGILIATLPPLFGQPWQEWVIRATVFIVAAAPCALVISIPITLVAALGTASRNGILLKGGLYLE
QLVKIKVIALDKTGTLTQGKPKVTDIIPLNNHTRNQILNAAATLESRSQHPMAQAILQQANEENIQYNPVEQFKSLTGSG
VLGFINGEKFYIGNPKLFIDMGLLIETLTQEINKLQAAGKTVVLLGTDKEILGLIAIADPLRPTARQMVSNLKSMGIERV
VMLTGDNLITASSIGEQAGVDEVFSDLSPEDKTRKIEELERRYGKVMMVGDGVNDAPALAAAHVGVAMGAVGTDVALETA
DVALMGDNLLKLPYLIAFSRRTWNIILQNLGLSIIVISSLVVGAITGYFTLPIAVLAHEISELIVIASGLRMLKS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SE0075 NP_763630.1 cadmium resistance protein B Not tested SCCpbp4 Protein 8e-123 46
cadA BAC57487.1 Probable cadmium-transporting ATPase (Cadmium efflux ATPase) Not tested Type-IIIinv SCCmec Protein 4e-121 45
unnamed BAB47609.1 cadmium resistance protein B Not tested Type-III SCCmec Protein 4e-121 45

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
lpg1010 YP_095043.1 cadmium efflux ATPase BAC0092 Protein 4e-101 44
lpg1010 YP_095043.1 cadmium efflux ATPase BAC0298 Protein 1e-94 44
lpg1010 YP_095043.1 cadmium efflux ATPase BAC0100 Protein 6e-87 42
lpg1010 YP_095043.1 cadmium efflux ATPase BAC0124 Protein 9e-87 42