Gene Information

Name : clpB (HD0565)
Accession : NP_873111.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease subunit B
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 431865 - 434435 bp
Length : 2571 bp
Strand : -
Note : -

DNA sequence :
ATGAATTTCGAAAAATTTACAACTAAATTGCAAGAAGCATTAAATGAAGCACAATCATTAGCAGTCGCCAAAGATAATGC
CTATATTGAACCGGTTCATTTACTTTATGCCTTAGTAAAACAACAAGATGGTGCAATCGCCCCGTTATTTACTACCTTAA
ATGTATCAACCCAAACGTTAATCAACGAGTTAGAACTGATCTTAAATCAATTACCACAAGTAACCGGCACAACAACACAA
GCATCACAACAACTTATTCGTTTATTAAATCAAACGGCTAAATTAGCCCAACAATTTAACGACAGCTTTATTTCATCAGA
ATTATTTTTACTGGCTGCATTAGATGATCATGGCAGCTTAGGTAAATTATTTAAAGCATTTGGCTTAACAAAAGAAAACG
TCACGCAAGCAATCAGCCAAATGCGAGGAGGAGAGAGTGTGAACAATCAGAATGCAGAGCAAACAAGACAAGCATTACAA
AAATATACCATTGATTTAACTGAACGCGCCAAAACAGGCAAATTAGATCCCGTGATTGGCCGTGATGAAGAAATTCGCCG
TACCGTACAAGTATTACAACGCAGAACTAAAAATAATCCCGTATTAATCGGCGAACCCGGAGTGGGTAAAACCGCCATTG
TTGAAGGCCTAGCACAACGTATTGTGAATGGAGAAGTACCAGAAGGTTTAAAAAATAAACGCGTATTATCATTAGATATG
GGCGCACTTATTGCGGGAGCAAAATATCGAGGTGAATTTGAAGAACGTTTAAAAGCGGTATTAAATGAACTCGCCAAAGA
AGAAGGGCAAGTTATTTTATTTATTGACGAAATTCATACGATGGTAGGCGCGGGTAAAACCGATGGCGCAATGGATGCTG
GCAACCTATTAAAACCAAGTTTAGCGCGCGGTGAATTACATTGCGTTGGCGCAACTACCCTAGATGAATATCGACAATAT
ATTGAAAAAGATGCCGCGCTAGAACGCCGTTTCCAAAAAGTTTTAGTTGATGAACCAAGTGTTGAAGACACCATTGCTAT
TTTACGTGGCTTAAAAGAACGTTATGAAATTCATCATCACGTACAAATTACTGATCCAGCCATTGTAGCTGCTGCAACGC
TTTCTCATCGTTATATTAGCGATCGCCAATTACCGGATAAAGCGATTGATTTAATTGATGAAGCAGCTTCTAGTTTACGT
ATGGAAATAGATTCTAAACCAGAGCCATTAGATAAACTCGAGCGCCGTATTATTCAATTAAAATTGGAACGCCAAGCGCT
CCAAAAAGAAAAAGATGAAGCTAGTCGCCAACGGCTTGCAAAATTAGATGAAGAAATGACCGCTAAAGCACAAGAATATT
CAGCACTTGAAGAAGTGTGGAAAGCGGAAAAATCTGCTTTACTTGGCACACAACATCTTAAAACAGAATTAGAAAATGCA
CGCATTGCAATGGATCAAGCCAAACGTGCAGATAATTTTGAAAAAATGTCAGAATTACAATATGGCACCATTCCAGCATT
AGAAAAACAGCTGCAAGACGCCATTAAACGTGAAGAGGAAAACAATGATCACCATTTGTTACGTACTAAAGTAACCGAAG
AAGAAATTGCAGAAGTATTATCAAAAGCGACAGGAATTCCGATCACAAAAATGATGGAAGGCGAAAAAGAAAAATTACTG
CGTATGGAACAAGTATTACATAGCCGAGTTATCGGGCAAAATGAGGCCGTAGAAGCAGTAGCAAATGCGATTCTCCGTAG
CCGTGCAGGGCTTGCTGATCCAAATAAACCCATTGGTTCATTTTTATTCCTTGGGCCAACCGGGGTCGGTAAAACTGAGC
TAAGCAAAACATTAGCCAACTTTTTATTTGATGATGAAAATGCCATCGTGCGGATCGATATGTCAGAATTTATGGAAAAA
CATAGCGTATCACGCTTAGTCGGGGCACCTCCCGGCTATGTAGGTTATGAACAAGGGGGCTATTTAACTGAAGCAGTTCG
TCGCCGTCCATATTCTGTAGTCTTACTAGATGAAGTAGAAAAAGCCCACCCTGATGTGTTTAATATCTTATTACAAGTAT
TAGATGACGGGCGTTTAACCGATGGACAAGGTAGAACGGTGGATTTCCGCAACACTGTAGTAATTATGACTTCAAATTTA
GGCGCACATTTGATCCAAGAAAATGCAGAAATCACTTATTTAGCGATGAAAGAAATGGTAATGTCAGTGGTAAGTCAACA
CTTCCGCCCTGAATTTATCAACCGTATTGATGAAACCGTGGTCTTCCATCCACTCGATCAACAGCATATTCGTGCCATTG
CTAATATTCAATTACAGCGGTTGATACGACGGCTTGCTGAACGTGGCTACCAAGTGACAATAAGTGATACCGCCTTAGAT
CATATCAGCCAAGCGGGCTTCGACTCTTTATTTGGTGCTCGTCCATTAAAACGTGCGATCCAACAAGAGCTTGAAAACCC
TCTTGCACAACAAATATTAAGTGGCAAATTATTGCCAAATAATCCTGTGATTATTGATTATCAAGATAATCACATCATTG
CTAAACAATGA

Protein sequence :
MNFEKFTTKLQEALNEAQSLAVAKDNAYIEPVHLLYALVKQQDGAIAPLFTTLNVSTQTLINELELILNQLPQVTGTTTQ
ASQQLIRLLNQTAKLAQQFNDSFISSELFLLAALDDHGSLGKLFKAFGLTKENVTQAISQMRGGESVNNQNAEQTRQALQ
KYTIDLTERAKTGKLDPVIGRDEEIRRTVQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIVNGEVPEGLKNKRVLSLDM
GALIAGAKYRGEFEERLKAVLNELAKEEGQVILFIDEIHTMVGAGKTDGAMDAGNLLKPSLARGELHCVGATTLDEYRQY
IEKDAALERRFQKVLVDEPSVEDTIAILRGLKERYEIHHHVQITDPAIVAAATLSHRYISDRQLPDKAIDLIDEAASSLR
MEIDSKPEPLDKLERRIIQLKLERQALQKEKDEASRQRLAKLDEEMTAKAQEYSALEEVWKAEKSALLGTQHLKTELENA
RIAMDQAKRADNFEKMSELQYGTIPALEKQLQDAIKREEENNDHHLLRTKVTEEEIAEVLSKATGIPITKMMEGEKEKLL
RMEQVLHSRVIGQNEAVEAVANAILRSRAGLADPNKPIGSFLFLGPTGVGKTELSKTLANFLFDDENAIVRIDMSEFMEK
HSVSRLVGAPPGYVGYEQGGYLTEAVRRRPYSVVLLDEVEKAHPDVFNILLQVLDDGRLTDGQGRTVDFRNTVVIMTSNL
GAHLIQENAEITYLAMKEMVMSVVSQHFRPEFINRIDETVVFHPLDQQHIRAIANIQLQRLIRRLAERGYQVTISDTALD
HISQAGFDSLFGARPLKRAIQQELENPLAQQILSGKLLPNNPVIIDYQDNHIIAKQ

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
STY0294 NP_454876.1 ClpB-like protein Not tested SPI-6 Protein 1e-110 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpB NP_873111.1 ATP-dependent Clp protease subunit B VFG2076 Protein 8e-121 42
clpB NP_873111.1 ATP-dependent Clp protease subunit B VFG2084 Protein 9e-114 41