Gene Information

Name : pepA (HD0555)
Accession : NP_873102.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Unknown
Product : leucyl aminopeptidase
Function : -
COG functional category : E : Amino acid transport and metabolism
COG ID : COG0260
EC number : -
Position : 425279 - 426778 bp
Length : 1500 bp
Strand : +
Note : catalyzes the removal of N-terminal amino acids preferably leucine from various peptides

DNA sequence :
ATGGAATTTAGTGTACAAAGTAGCACGATTGAACAATTACAAACAGAATGCTTGATTGTGGGGGTTTATCAAGATCATCA
ATTATCATCAGCCGCGGTCCAATTAGATCAAGTAAGTGGTGGATATCTAACACGTTTATTGCAAATGGGGGATTTAGATG
GTTCAGTCGGACAAAGTTTATTATTACATAATGTGCCAAATATCAAATCAGCGCGGGTGTTATTAGTCGGTTGTGGCAAA
CAAGATGAATTAACCGAAAGTCAGTATAAAAAAATTATGCAACAAATGATGCATGCCATTAATGCCACGGCGGTTCAGCA
AGCGGTCTGTTTTTTAACCGAATTAATGGTGAAGCAACGTACAATTTACTGGAATATTCGTTTTGCGATAGAAAGCATTC
AAGCTAGTCGCTATGTGTATGATGTATTTAAAAGCATAAAAGCGAAGGTTGTGGGTAAGTTAACGCAGATTATTTTTAAT
GTGGCTAATCAACAAGATTTGCTTGAGGCAGAACGTGGGTTAAAGCACGCACAAGCGATTGCAAGCGGTATGATTTATGC
AAAAAATATGGCGAATTGTCCACCTAATATTTGTAATCCGGCTTATTTAGCTGAATTAGCTCAAGGATTAGCCACTGATT
ATCAACAGATTCAGACGCGGATTGTAGATGAAGCAGAGATGGCAACCTTAGGTATGAATGCGTATTTAGCGGTGTCTCAA
GGATCGCATAATCCCGCCTTTTTATCAGTGATTGAATATAATCATCATCCTGATCCAAGCGCTAAACCGATTGTATTAGT
AGGTAAAGGCTTAACATTTGATGCGGGGGGCATTTCGCTCAAACCATCTGATGCAATGGATGAAATGAAATATGATATGG
GCGGTGCGGCTGCGGTTTATGGCACGATGAAAGCACTAGCGGAAATGCAATTACCATTAAATGTAGTGGGTATTCTTGCC
GGTTGTGAAAATATGCCAGATGGCAACGCTTATCGCCCAGGGGATATCTTAACTACGATGAATGGTTTAACGGTGGAAGT
ATTAAATACGGATGCTGAAGGTCGTTTAGTATTATGCGATGCATTAACTTATGTAGAACGTTTTGATCCCGCTTGTGTGA
TTGACATTGCTACCCTAACAGGGGCTTGTATGGTTGCTTTAGGGACACACAATAGCGGTTTAATGTCTACGCATAATGAG
TTGGCTGATGAGTTATTCACTGCAGCAAGCCAGGCAAATGATAAAGTATGGCGTTTACCTCTAGGTGAAGAATATCAAGA
GCAATTGAAGTCAAATTTTGCCGATCTTGCTAATATTGGTGGTCGTTTTGGTGGGGCTATTACGGCAGGACAATTTTTAT
CTAACTTTACGCAAAAATACCGTTGGGCTCATTTAGATATCGCCGGCACGGCTTGGCAATCAGGCGTAGCAAAAGGCGCA
ACAGGCAGACCTGTGCCATTACTTGCGCAATTCCTAATAAATAGGGCTCAACAGGAATAA

Protein sequence :
MEFSVQSSTIEQLQTECLIVGVYQDHQLSSAAVQLDQVSGGYLTRLLQMGDLDGSVGQSLLLHNVPNIKSARVLLVGCGK
QDELTESQYKKIMQQMMHAINATAVQQAVCFLTELMVKQRTIYWNIRFAIESIQASRYVYDVFKSIKAKVVGKLTQIIFN
VANQQDLLEAERGLKHAQAIASGMIYAKNMANCPPNICNPAYLAELAQGLATDYQQIQTRIVDEAEMATLGMNAYLAVSQ
GSHNPAFLSVIEYNHHPDPSAKPIVLVGKGLTFDAGGISLKPSDAMDEMKYDMGGAAAVYGTMKALAEMQLPLNVVGILA
GCENMPDGNAYRPGDILTTMNGLTVEVLNTDAEGRLVLCDALTYVERFDPACVIDIATLTGACMVALGTHNSGLMSTHNE
LADELFTAASQANDKVWRLPLGEEYQEQLKSNFADLANIGGRFGGAITAGQFLSNFTQKYRWAHLDIAGTAWQSGVAKGA
TGRPVPLLAQFLINRAQQE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00295 YP_008207760.1 Leucyl aminopeptidase Not tested AbaR25 Protein 2e-89 51
BJAB0868_00299 YP_008211625.1 Leucyl aminopeptidase Not tested AbaR26 Protein 2e-89 51