Gene Information

Name : kdsB (HD0334)
Accession : NP_872922.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 263881 - 264642 bp
Length : 762 bp
Strand : +
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAAATTTACAGTAATTATTCCTGCCCGCTATGCTTCAAGCCGTTTGCCGGGTAAGCCATTATTAGATATTAATGGCTA
TCCTATGATTCAATATGTTTGGCAGAAAGCACAACAAGCGGGAGCAAATCGTGTCATTATTGCCACTGATCATCCACAAA
TTCAAACGGTGGCTAAAGCTTTTGGGGCAGAAGTTTGTATGACTTCTGATCAACATCAATCTGGCACTGAACGTTTGGCG
GAAGTGGTAGCGAAAATGGCGATTGCAGATCAGGAAATTATTGTTAATGTACAAGGCGATGAACCGTTAATTCCACCGAT
TATTGTGCAACAAGTCGCAACTAATTTGGATAAAAACGGTGTAAATATGGCAACGCTAGCGGTCAAATTAACTACTCGTG
AAGAGCTATTTAATCCGAATGTTGTGAAAACGGTGATTAATGACAAAGGAATGGCGCTTTATTTTTCTCGAGCCGCAGTG
CCATTTGCACGAGATCATTTTTCTGAATGTGATGATACTTTTGTCGCAAGCCAATGTTATTTGCGCCATATTGGGATTTA
TGCTTATCGAGCTGGCTTTATTAAACAGTATGTTGCTTGGCAGCCGACGGTGTTAGAACAATTAGAGTCGTTAGAGCAAC
TGCGTGCTTTATGGTATGGCGAGCAAATTCACGTTGAGCTAGCTAAGCAAGCTCCTGCCTTGGGCGTGGATACTGCACAA
GATTTAGCGCGAGTACGGCAAATGTTAAGCCAAACCGTTTAA

Protein sequence : 
MKFTVIIPARYASSRLPGKPLLDINGYPMIQYVWQKAQQAGANRVIIATDHPQIQTVAKAFGAEVCMTSDQHQSGTERLA
EVVAKMAIADQEIIVNVQGDEPLIPPIIVQQVATNLDKNGVNMATLAVKLTTREELFNPNVVKTVINDKGMALYFSRAAV
PFARDHFSECDDTFVASQCYLRHIGIYAYRAGFIKQYVAWQPTVLEQLESLEQLRALWYGEQIHVELAKQAPALGVDTAQ
DLARVRQMLSQTV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 1e-39 42
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 3e-38 41
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 2e-38 41