Gene Information

Name : murD (HD0245)
Accession : NP_872842.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Unknown
Product : UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG0771
EC number : 6.3.2.9
Position : 185927 - 187234 bp
Length : 1308 bp
Strand : +
Note : UDP-N-acetylmuramoylalanine--D-glutamate ligase; involved in peptidoglycan biosynthesis; cytoplasmic; catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine during cell wall formation

DNA sequence :
ATGATGCAAAATCAATATCAAGGCAAAATAATTACGATTGTCGGTTTAGGTAAGACGGGCCTTTCTTGTGTGGCATTCTT
TGCAGAAAAACAAGCAACAATACAAGTGATTGATACACGAGAACAACCTGCAGGAATTGAGCATTTATCAGACAATGTCG
CATTGCATACCGGTAGCCTAAACCTAGAGTGGCTATTAGCGTCAGATTTAATTGTAATGAGTCCCGGTTTAGCATTAGCC
ACGCCCGAAATCCAAACCGCTATTCAGGCTGGTATTGAAGTTGTTGGTGATATTGAATTATTTGTCCGTGAGGCTAAAGC
ACCGATTATTGCGATTACTGGTTCAAATGGTAAAAGTACAGTGACCACGCTAGTGAGTGAAATGGCACAACAAGCGGGCA
TAAAAGTCGGTATGGGTGGTAATATTGGTATTCCCGCCTTAAGTTTGTTAAATAAAGGATATGAGCTGTTTGTGCTGGAA
CTTTCTAGTTTTCAGTTAGAAACGACCTATTCTTTAAAAGCAAAGGCAGCAACCATTTTGAATGTTAGCCAAGACCATAT
GGATCGCTATGCTTCAGGTGAGCATTATCGGCAAGCGAAATTGCGTATTTATGAAAATGCTGAATACGTGATTGTGAATG
ATGACGATCCACTTACTTATCCACTGCCGTCACAATCGGTGGGTAACTTGCGGCATTTTGCGGAACATGATGCACAGTAT
GCTATAAAGTATGATCAGCTTTGCAGTGGTGATCAAGCGGTGATTAATACGGATCAAATGTTATTAACAGGTCGCCATAA
TCAATTGAATGCTTTGGCTGCTATTGCTTTGGCAGAGGCAGCGGGCATTAATCGAACGGGCATTATCAATGGGTTACGCT
GTTATGGTGGATTAGCTCACCGCTTTCAACGGGTGCCAACGAATGATGGTGTATGTTGGGTGAATGATTCAAAAGCAACG
AATGTTGGTAGTACAGTGGCTGCGTTAAATGGCTTACCGCTATCAGGTACTCTTTATTTATTATTGGGTGGTGATGGAAA
AGGGGCAGATTTTTCAATGTTAAAAGCATTAGTTAATCAGCCACATATTGTGTGTTATTGCTTTGGTAAAGATGGAAAAT
CATTAGCTGAATTAACGACTAACAGTGTGTTAGTGGATACCATGCAACAAGCAATTGAGCAAATTCGTCCGCTTGTTAAG
CAAGGGGATATGGTTTTGTTATCACCAGCGTGTGCCAGTTTAGATCAATTTAATAATTTTGAAGAGCGTGGCGATATGTT
TGCACGATTAGCGCAACAAGCAGTTTAA

Protein sequence :
MMQNQYQGKIITIVGLGKTGLSCVAFFAEKQATIQVIDTREQPAGIEHLSDNVALHTGSLNLEWLLASDLIVMSPGLALA
TPEIQTAIQAGIEVVGDIELFVREAKAPIIAITGSNGKSTVTTLVSEMAQQAGIKVGMGGNIGIPALSLLNKGYELFVLE
LSSFQLETTYSLKAKAATILNVSQDHMDRYASGEHYRQAKLRIYENAEYVIVNDDDPLTYPLPSQSVGNLRHFAEHDAQY
AIKYDQLCSGDQAVINTDQMLLTGRHNQLNALAAIALAEAAGINRTGIINGLRCYGGLAHRFQRVPTNDGVCWVNDSKAT
NVGSTVAALNGLPLSGTLYLLLGGDGKGADFSMLKALVNQPHIVCYCFGKDGKSLAELTTNSVLVDTMQQAIEQIRPLVK
QGDMVLLSPACASLDQFNNFEERGDMFARLAQQAV

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00311 YP_008207776.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR25 Protein 2e-53 41
BJAB0868_00315 YP_008211641.1 UDP-N-acetylmuramoylalanine-D-glutamate ligase Not tested AbaR26 Protein 2e-53 41