Gene Information

Name : nanE (HD1852)
Accession : NP_874204.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Virulence
Product : N-acetylmannosamine-6-phosphate 2-epimerase
Function : -
COG functional category : G : Carbohydrate transport and metabolism
COG ID : COG3010
EC number : 5.1.3.9
Position : 1555079 - 1555768 bp
Length : 690 bp
Strand : -
Note : Converts N-acetylmannosamine-6-phosphate to N-acetylglucosamine-6-phosphate

DNA sequence : 
ATGTCAAAATTATCGCATTCTGAAGTATTAATAATGATTCAAGGTGGCTTAGTGGTCTCTTGTCAACCTGTAGATGATGG
CCCTATGGATCAGCCCGCAATTGTGGCAGCTATGGCGCAAGCCGCAATTGTGGGGGGCGCAGTAGGAGTAAGAATTGAAG
GTGTGCAAAATTTAAAAGCAACGCGTCCAATGGTAACAGCTCCGATTATCGCCATTGTAAAACGGGATTTACCAGAGAGC
GCTGTACGGATTACGCCATTTTTAGCGGATATTGATCAATTAGCGGCCGCTGGTGCTGATATTATCGCAGTAGATGGCAC
GGATAGAGAACGTCCGGTGGCTGTAGTTGCCGCGTTGGAACGCATTCATGCCCAAGGTTGTTTAGCTATGGCAGACTGTT
CGACTTTAGCCGAAGGGCTATATTGTCAGCAATTAGGCTTCGATATTATTGGCAGTACGATGTCTGGTTATACGGGAGGC
GAATTGCCTGTGGAACCAGATTATCAATTAGTCAAAGATTTAAAATCTGCCGGTTGTTATGTGATGGCAGAAGGTCGCTA
TAATTCCCCCGCATTGGCTAAAAGCGCGATGCAAATGGGCGCAGACTGTGTAACAGTTGGATCAGCGTTAACACGGCTAG
AACATATGGTGAGTTGGTTTGCTGTTGCGGTGCAATCTGCTAAGGAATAA

Protein sequence : 
MSKLSHSEVLIMIQGGLVVSCQPVDDGPMDQPAIVAAMAQAAIVGGAVGVRIEGVQNLKATRPMVTAPIIAIVKRDLPES
AVRITPFLADIDQLAAAGADIIAVDGTDRERPVAVVAALERIHAQGCLAMADCSTLAEGLYCQQLGFDIIGSTMSGYTGG
ELPVEPDYQLVKDLKSAGCYVMAEGRYNSPALAKSAMQMGADCVTVGSALTRLEHMVSWFAVAVQSAKE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
VC0395_A1378 YP_001217321.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 3e-37 52
VC1781 NP_231416.1 N-acetylmannosamine-6-phosphate 2-epimerase Not tested VPI-2 Protein 2e-37 52
nanE ACA01846.1 N-acetylmannosamine-6-phosphate epimerase Not tested VPI-2 Protein 2e-37 52

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
nanE NP_874204.1 N-acetylmannosamine-6-phosphate 2-epimerase VFG1114 Protein 7e-38 52