Gene Information

Name : topB2 (HD1276)
Accession : NP_873711.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Unknown
Product : DNA topoisomerase III
Function : -
COG functional category : L : Replication, recombination and repair
COG ID : COG0550
EC number : -
Position : 1038166 - 1040085 bp
Length : 1920 bp
Strand : +
Note : decatenates replicating daughter chromosomes

DNA sequence :
ATGATGCGAGTGTTTTTAGCCGAAAAACCGAGTTTAGCCCGTGCGATTGCTGAAGTATTGCCTAAACCTCATATCCGAGG
CGATGGTTATATTCAATGTGGTGAACATGATTATGTGACTTGGTGTATAGGCCATTTACTTGAACAGGCAGAGCCAGATG
CATATGATGAACGTTTTAAAACTTGGCGAATGGAGCATTTACCGATTATTCCACAGCAATGGAAATTAATTGCTAAAAAA
CAAACCGCTAAACAGCTTAAAGTGGTCGAAAAATTAGTTAAGAAAGCAGAAATATTAGTCAATGCGGGCGACCCTGATAG
AGAAGGCCAATTATTAGTTGATGAAGTATTTAATTATTTAAATGTGCCAGCGAGTAAAAAAAGCCAAATACAACGCTGTC
TAGTTAGTGACCTTAATCCAACTGCAGTCAGTAAGGCGATCAATAAATTACAAAATAATTGTGATTTTATACCGCTTGCC
ACTTCTGCGTTAGCACGCGCAAGAGCGGATTGGTTGTATGGCATTAATATGACTAGGGCCTATACTCTACAAGGCCGTTG
GGTTGGTTATCAAGGCGTGCTTTCAGTCGGGCGCGTACAAACGCCTGTATTAGGTTTGATTGTACGGCGTGATCTTGAGA
TCGAACATTTTACACCTAAAGATTATTTTGAAGTTTTAGCACATATCATTGTGCCAACCACACAAGAAAGATTTACCGCC
CACTGGCAGCCAAGTAAAGCGTGTGAAGATTACCAAGATGAAGAAGGAAGAGTACTCTCGCGCGCATTGGTGGAAAATGT
TGTTAAACGTATCAGTGATCAAACCGCTTGCGTGACTGATTATCAAGATAAAACCGAAAGTGAAATAGCGCCTTTACCTT
ATTCGCTTTCAGCATTACAGATTGATGCCGCACGCCGTTATGGTCTATCGGCTCAAGCAGTATTAGATATTTGCCAAACC
TTATATGAAACCCACAAATTAATTACTTATCCTCGTTCAGATAATCGTTATTTACCAAATGAACATTATAATGAACGATT
TAACGTCGTGGCAGCGATTGCACATCATCTAACAGAATATCAACAAAAACCCGAAGTCGTTAACTTAGCATTACGTGGCC
GTTGTTGGAATGATAAAAAAATAGAAGCACATCACGCCATTATTCCGACCGCTAGGCAAGGCAATCTGCGACTCACTGAA
AATGAAAAAAGGATTTATCGCTTGATCGCTTGTCAATATTTAATGCAATTTTGCCCAGATGCAGAATATAGCAAAAGAAA
AATTACTTTAGATATTGCGGGAGGCACGTTTATTGCTCAAGCTAGAAATTTAGTGACTGCAGGTTGGAAAGCCTTATTAG
GTAAGGAAGACTGCGATGAAATGATTGAACCATTGTTACCCGCAGTACAGAAAGCACAACGACTGCATTGTGAGAAAAGG
GAAATTATCAGTAAAAAAACACAACTGCCACGCCATTTCACTGATGCAAGTTTGTTATCCGCTATGACAGGTATTGCACG
TTTTGTGCAAGATAAACAGCTTAAAAAAATACTACGTGAAACAGATGGTTTGGGTACAGAAGCCACTCGTGCAGGTATTA
TTGAATTGCTCTTTAAACGCGGTTTTGTTACCAAAAAAGGGCGTAATATTCAAAGTACTGAAACAGGACGAGTTTTAATT
AGCGCCTTGCCAGATATAGCGACTCAACCAGATATGACTGCCCAATGGGAAATGCAACTGAAACAAATTAGCCAAAAACA
AGTCTCTTACCAACAATTTATGCACCAATTAACGACTAAATTACCCGAGCTACTGCATACAGACCGACAAAAATTGCAAA
AACTCAACATAATTACACCGCTTAAGCTACCTGCTAAGCGAACACATACTAAAGCATCAATAATGGCTGATGAAAAATAA

Protein sequence :
MMRVFLAEKPSLARAIAEVLPKPHIRGDGYIQCGEHDYVTWCIGHLLEQAEPDAYDERFKTWRMEHLPIIPQQWKLIAKK
QTAKQLKVVEKLVKKAEILVNAGDPDREGQLLVDEVFNYLNVPASKKSQIQRCLVSDLNPTAVSKAINKLQNNCDFIPLA
TSALARARADWLYGINMTRAYTLQGRWVGYQGVLSVGRVQTPVLGLIVRRDLEIEHFTPKDYFEVLAHIIVPTTQERFTA
HWQPSKACEDYQDEEGRVLSRALVENVVKRISDQTACVTDYQDKTESEIAPLPYSLSALQIDAARRYGLSAQAVLDICQT
LYETHKLITYPRSDNRYLPNEHYNERFNVVAAIAHHLTEYQQKPEVVNLALRGRCWNDKKIEAHHAIIPTARQGNLRLTE
NEKRIYRLIACQYLMQFCPDAEYSKRKITLDIAGGTFIAQARNLVTAGWKALLGKEDCDEMIEPLLPAVQKAQRLHCEKR
EIISKKTQLPRHFTDASLLSAMTGIARFVQDKQLKKILRETDGLGTEATRAGIIELLFKRGFVTKKGRNIQSTETGRVLI
SALPDIATQPDMTAQWEMQLKQISQKQVSYQQFMHQLTTKLPELLHTDRQKLQKLNIITPLKLPAKRTHTKASIMADEK

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
topB1 YP_005176228.1 DNA topoisomerase III Not tested ICEPmu1 Protein 2e-99 41