Gene Information

Name : serS (HD1133)
Accession : NP_873606.1
Strain : Haemophilus ducreyi 35000HP
Genome accession: NC_002940
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 901412 - 902719 bp
Length : 1308 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGATCGACCAAAATTTACTTCGCACTAATTTAGACGATGTTGCAAATGCGCTCAAATTAAAACGTAATTTCATCTTAGA
TGTTAACCAAGTAAAAGCACTTGAAGAACAACGTAAAACATTACAAGTCACAACGGAAACCTTGCAAGCTGAACGTAATG
CTCGTTCGAAAAATATTGGCGCAGCTAAAGCACGTGGTGAAAACATTAGCCAACTATTAGCTGAAGTAGACACTATGGGT
AATCAGCTTGAGATAGCAAAAACAGAATTAGATAAAGTACAAAGTGAAATACGTGAATTATTGTTAACTATTCCAAATTT
ACCGGCGGAAGAAGTCCCGCTTGGTAAAGATGATAGCCAAAATAAAGAAATATTACGCTGGGGAACGCCTCGTCAATTTG
ATTTTGAAATCAAAGATCACGTCACGCTTGGTGAAAACTTAAAAGGCATCGATTTTCCTACGGGCGTCAAGTTAACCGCA
AGTCGCTTTGTTGTAATGAAAGACAAAATTGCCCGCTTACACCGTGCATTAGCACAATTTATGTTAGATCTACATAGCGA
ACAACACGGTTATATGGAAGTAAATGTCCCCTTATTGGTCAATCACGACACCTTGTATGGCACAGGTCAACTGCCAAAAT
TTGGTGAAGATCTATTCCATACTCAACCATTAACTGGACAAGATCCTAATGAAGTGCAACGCCCTTATGGTTTAATTCCC
ACCGCTGAAGTTCCGCTAACCAATCTCGTGCGTGATGAAATTGTGGATGAAGATAGTCTGCCAATTAAACTCGTTGCCCA
TACACCTTGTTTCCGTGCAGAAGCAGGTTCTTATGGACGTGATACACGCGGTCTAATACGTATGCATCAATTTGAAAAAG
TCGAATTAGTACAAATTGTGGCACCGGAAAAATCCATGGAAGCACTTGAAGAATTAACAGGTCAAGCAGAAAAAATCTTA
CAACTACTCCATTTACCTTACCGTAAAGTATTACTATGCACAGGCGATATGGGCTTTGGCTCAGCAAAAACATATGACTT
AGAAGTCTGGTTACCGGCACAAAATACTTACCGTGAAATTTCTTCTTGCTCAAATATGTGGGATTTCCAAGCTCGTCGGA
TGTCTGCTCGCTGTAAAGCAAAAGGCGATAAAAAAACACGTTTAGTTCATACCTTAAATGGCTCAGGGCTAGCAGTTGGA
CGGACGTTAGTCGCTGTATTAGAAAATTATCAAAATGCCGACGGCTCGATCACTATCCCAGAAGTATTGCGTCCGTATAT
GGCTGGACAAGAAGCAATTACCGGCTAA

Protein sequence :
MIDQNLLRTNLDDVANALKLKRNFILDVNQVKALEEQRKTLQVTTETLQAERNARSKNIGAAKARGENISQLLAEVDTMG
NQLEIAKTELDKVQSEIRELLLTIPNLPAEEVPLGKDDSQNKEILRWGTPRQFDFEIKDHVTLGENLKGIDFPTGVKLTA
SRFVVMKDKIARLHRALAQFMLDLHSEQHGYMEVNVPLLVNHDTLYGTGQLPKFGEDLFHTQPLTGQDPNEVQRPYGLIP
TAEVPLTNLVRDEIVDEDSLPIKLVAHTPCFRAEAGSYGRDTRGLIRMHQFEKVELVQIVAPEKSMEALEELTGQAEKIL
QLLHLPYRKVLLCTGDMGFGSAKTYDLEVWLPAQNTYREISSCSNMWDFQARRMSARCKAKGDKKTRLVHTLNGSGLAVG
RTLVAVLENYQNADGSITIPEVLRPYMAGQEAITG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 1e-103 54