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Name : leuS (HD1132) Accession : NP_873605.1 Strain : Haemophilus ducreyi 35000HP Genome accession: NC_002940 Putative virulence/resistance : Unknown Product : leucyl-tRNA synthetase Function : - COG functional category : J : Translation, ribosomal structure and biogenesis COG ID : COG0495 EC number : 6.1.1.4 Position : 898676 - 901261 bp Length : 2586 bp Strand : - Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl DNA sequence : ATGCAACAACAATATAACCCAAGTGCTATTGAATCTAAGGTTCAACATTTCTGGGAAGAAAATAAAGTTTTCAAAGCAGT AAAAGATATAACAAAAGAAAAATATTACTGCCTTTCAATGTTACCGTATCCATCTGGTCGCTTGCATATGGGGCATGTAC GTAACTATACCATTGGCGATGTTATTTCACGTTACCAACGGATGATCGGTAAAAATGTATTACAACCTATGGGATGGGAT GCTTTCGGCTTGCCTGCTGAAGGTGCGGCAGTTAAAAATAATACCGCTCCCGCAAAGTGGACCTATGAAAATATTGAATA TATGAAAAATCAATTAAAAGTATTAGGTTTTTCATATGATTGGGATCGCGAAATCACCACTTGCCGTCCTGAATATTACA AATGGGAACAATGGTTCTTCACTGAATTATATAAAAAAGGCTTAGTTTATAAAAAAACCTCTACCGTAAACTGGTGTCCA AATGATGAAACCGTATTAGCCAATGAACAAGTCCACGAAGGTTGTTGTTGGCGTTGTGATACACCGGTTGAACAACGTGA TATCCCTCAATGGTTTATTAAAATCACGGATTATGCAGAAGAATTATTAACGCAGTTAGATAACTTAACGCAATGGCCCG ATCAAGTAAAAACGATGCAACGCAACTGGATTGGCCGTTCTGAAGGGGTAGAGATTACGTTTAAAATCGCTGGCTCAAAT GCGACTTTACCCGTTTATACTACTCGCCCTGATACATTCTTTGGCGTAAGCTATTTAGCCGTGGCCGCAGCCCATCCACT GGCTGAATTAGCTTCAACCAATAATCCAGCATTAGCCGAATTTATTCGTGAAGCTAAAAATACCAAAGTGGCAGAAGCAG AGTTGGCAACCATGGAAAAAAAAGGAATGCCAACCGGTTTATTTGCTATCCATCCATTAACAGGTAAAGAAATACCGGTT TGGGTAGCTAATTTCGTATTAATGCACTATGGCACAGGCGCCGTGATGGCAGTCCCTGCTCACGATGAACGTGACTTCGA TTTTGCTAAAAAATATGGATTACAAATTAATCAAGTAATCCAACCGCTTGATGCATCAACTTGGGACTTTTCACAAGCCG CCTTTACTGAGCACGGTAAATTAATTAATTCAGCAGAATTTGATGGACTAGATTTCAATCATGCATTTAATGCCATTGCC GATAAATTAGAATCCCTTGGAGTTGGTAAACGCCAAGTTAACTTCCGCTTACGTGATTGGGGCGTTTCTCGTCAACGTTA TTGGGGCGCTCCCATTCCAATGATGACCACTGAACAAGGCGAAGTGGTTACCGTTCCATTGAAAGATTTACCGGTTATTT TGCCAGAAAATGTGGTAATGGATGGTGTACAAAGCCCCATTAAATCTGATCCTGAATGGGCAAAAACAACTTATGAAGGA CAACCTGCATTAAAAGAAACAGACACTTTCGATACTTTCATGGAATCATCATGGTATTATGCACGTTATACTTGCCCACA ATATCACCAAGGTATGTTAGATGCTGATGAAGCCAATTATTGGTTACCCGTCGATCAATATATCGGTGGTATTGAGCATG CAACCATGCATTTACTTTACTTCCGCTTCTTCCACAAATTACTACGTGATGCGGGCATTTTAACTTCAGATGAACCGGCA ACTAAACTACTCTGTCAAGGAATGGTATTAGCTGATGCGTTTTATTACACCAGCCCAACTAATGAACGTATCTGGGTAAG CCCAACGCAAGTCAGTTTAGAACGTGATGAAAAAGGCCGCATTATTAACGCAACAGATCCAGCGGGCCACAAATTAGTCC ATAGTGGTATGACCAAGATGTCAAAATCAAAAAACAATGGTATTGACCCGCAAGAAATGGTTGAAAAATATGGTGCTGAT ACTGTCCGCTTATTTATGATGTTTGCATCACCCGCCGAAATGACCCTTGAGTGGCAAGAATCTGGTGTCGAAGGCGCTAA ACGTTTCTTAGGTCGAGTATGGAATTTAGTTTATGAATATGTACAACAGCCGGCAACACAAGCATTAAATGCACTTGAAT TAAATAAAGCGCAAAAAGAATTACGCCGTGATGTACATAAAACCATTGCTAAAGTCAGCGATGATATTGGTCGACGTCAA ACATTTAATACCGCCATTGCGGCCATAATGGAATTGATGAATAAATTAAATAAAGCACCGCTTGAATCTGATCAAGATAA AGCCGTAATGGCAGAAGCATTAAGTGCCGTAGTTCGTATGCTTTATCCAATTACACCGCATATCTGTTTTGAGCTCTGGC AAGCATTAGGCAATCAACAAACTATTGATTTTGCACCTTGGGTCGTTTCTGATGAAACGGCGATGATAGAAGATGAAAAA TTAGTGGTTGTACAAGTCAATGGTAAAGTGCGTGGCAAAATAACCGTGCCCGCAAATGCTTCAGAAGATGAAGTGAAAAT AACTGCCAAAAATGATGCTAACGTAGCAAAATTCTTAGCTGATATGCAAATAGTCAAAGAGATCTATATACCATTTAAAA TGTTAAATTTTGTAGTTAAAGTATAA Protein sequence : MQQQYNPSAIESKVQHFWEENKVFKAVKDITKEKYYCLSMLPYPSGRLHMGHVRNYTIGDVISRYQRMIGKNVLQPMGWD AFGLPAEGAAVKNNTAPAKWTYENIEYMKNQLKVLGFSYDWDREITTCRPEYYKWEQWFFTELYKKGLVYKKTSTVNWCP NDETVLANEQVHEGCCWRCDTPVEQRDIPQWFIKITDYAEELLTQLDNLTQWPDQVKTMQRNWIGRSEGVEITFKIAGSN ATLPVYTTRPDTFFGVSYLAVAAAHPLAELASTNNPALAEFIREAKNTKVAEAELATMEKKGMPTGLFAIHPLTGKEIPV WVANFVLMHYGTGAVMAVPAHDERDFDFAKKYGLQINQVIQPLDASTWDFSQAAFTEHGKLINSAEFDGLDFNHAFNAIA DKLESLGVGKRQVNFRLRDWGVSRQRYWGAPIPMMTTEQGEVVTVPLKDLPVILPENVVMDGVQSPIKSDPEWAKTTYEG QPALKETDTFDTFMESSWYYARYTCPQYHQGMLDADEANYWLPVDQYIGGIEHATMHLLYFRFFHKLLRDAGILTSDEPA TKLLCQGMVLADAFYYTSPTNERIWVSPTQVSLERDEKGRIINATDPAGHKLVHSGMTKMSKSKNNGIDPQEMVEKYGAD TVRLFMMFASPAEMTLEWQESGVEGAKRFLGRVWNLVYEYVQQPATQALNALELNKAQKELRRDVHKTIAKVSDDIGRRQ TFNTAIAAIMELMNKLNKAPLESDQDKAVMAEALSAVVRMLYPITPHICFELWQALGNQQTIDFAPWVVSDETAMIEDEK LVVVQVNGKVRGKITVPANASEDEVKITAKNDANVAKFLADMQIVKEIYIPFKMLNFVVKV |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| leuS | YP_281511.2 | leucyl-tRNA synthetase | Not tested | Not named | Protein | 6e-156 | 42 |
