Gene Information

Name : pilR (GSU1495)
Accession : NP_952546.1
Strain : Geobacter sulfurreducens PCA
Genome accession: NC_002939
Putative virulence/resistance : Virulence
Product : sigma-54-dependent transcriptional response regulator PilR
Function : -
COG functional category : T : Signal transduction mechanisms
COG ID : COG2204
EC number : -
Position : 1640715 - 1642091 bp
Length : 1377 bp
Strand : +
Note : domains: REC, sigma54 interaction, HTH8

DNA sequence : 
ATGGAAATTCATGTTCTCGTAGTGGACGATGAACTGAGCATGCGCGAATTCCTCGCCATCCTGCTCGACCGGGAGGGCTA
TACCGTCGACCAGGCCGCCAGCGCCGAAGAGGCGCTGGCCTGTCTTGAACGCAAGACGTATGATCTGGTCATCTCCGACG
TAAAGATGCCGGGGCTTGATGGCATTACCCTCCTGGGCCGCATCAAGGAGATGACGCCCGACACTGCCGTCCTCCTCATG
ACGGCCTTTTCCACTGCCGAGCAGGCCGTGGAAGCCATGAAGCTCGGGGCGTACGACTACATTGCCAAACCCTTCAAGGT
GGAAGAGGTCAAGATTCTCGCCCGCAACGCCCTGGAAAAGAGGGATCTCAAGAGGGAGAACCTGCGGCTTCGCCAGGAGG
TGCAGGAGCGGTACAGCTTCAGCGGTCTGATCGGTAAGAGCAAGAAGATGCGCGAGGTCTACTCCCTGATCGAAAAAGTG
GCGCCAAGTACCGCGAATGTTCTCATTCTCGGTGAGAGCGGCACCGGCAAGGAGCTGGTGGCCCGCGCCATCCACTACAA
CAGCCAACGCAAGGGAAAACCCTTTGTGGCGGTCAACTGCGGCGCCATTCCCGAAACCCTCATGGAGAGTGAATTCTTCG
GTCACAAAAAGGGGGCGTTCACCGGCGCCGTTGGTGACCGGGCGGGGCTCTTCGAGCAGGCCGAGGGTGGTACCCTTTTC
CTGGACGAAATCGGAGAAGTGCCGCTCCAGCTTCAGGCCAAACTTTTGCGGGCCATCCAGGAAAAGGAATTCCGCAGGGT
AGGGGGAACCCTTGACCAGAAGGCCGACGTGCGGCTGGTGGCCGCCTCCAATCGTGATTTGGAAGAGCAGGTGAAGGAAG
GGAGTTTCCGGGAGGATCTCTTTTATCGCCTCAACGTGGTCCAGGTCAAAATGCCCCCACTCCGTGAGCGTGGAGATGAT
ATCCCCATCCTGGTTGAGCACTTTTACAAAAAGTACGTCCAGCCCCCCTACAGCGACCGCATCATAACCCAGGGGGCGCT
GAAGCTGCTCATGTCATACGGATTTCCGGGCAACGTCCGTGAGCTGGAGAACCTGGTCGAGCGCTGCTCCGTGCTCGGCA
ATCGCGAGATCTCGGAAGAATGTCTCCCGCCGCAGCTCCACGCGGGTAAACGGCCTGAATGTGGCGCGGTCACCGAGTGC
GAACTGCCGGAAGAGGGCATGGACCTCGAAGCCTACCTGGACGGCATTGAAAAGCGAATTCTGCTTCAGGCACTGGAACG
CAGCGGCGGTGTGAAAAAGAAGGCGGCCGAACTTTTGAAGCTTACGTTCCGTTCTTTCCGGTATCGCCTGGCAAAATTTG
GCATGGATGAGGAGTGA

Protein sequence : 
MEIHVLVVDDELSMREFLAILLDREGYTVDQAASAEEALACLERKTYDLVISDVKMPGLDGITLLGRIKEMTPDTAVLLM
TAFSTAEQAVEAMKLGAYDYIAKPFKVEEVKILARNALEKRDLKRENLRLRQEVQERYSFSGLIGKSKKMREVYSLIEKV
APSTANVLILGESGTGKELVARAIHYNSQRKGKPFVAVNCGAIPETLMESEFFGHKKGAFTGAVGDRAGLFEQAEGGTLF
LDEIGEVPLQLQAKLLRAIQEKEFRRVGGTLDQKADVRLVAASNRDLEEQVKEGSFREDLFYRLNVVQVKMPPLRERGDD
IPILVEHFYKKYVQPPYSDRIITQGALKLLMSYGFPGNVRELENLVERCSVLGNREISEECLPPQLHAGKRPECGAVTEC
ELPEEGMDLEAYLDGIEKRILLQALERSGGVKKKAAELLKLTFRSFRYRLAKFGMDEE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
BJAB07104_00300 YP_008207765.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR25 Protein 9e-73 41
BJAB0868_00304 YP_008211630.1 Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Not tested AbaR26 Protein 9e-73 41

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR NP_952546.1 sigma-54-dependent transcriptional response regulator PilR BAC0089 Protein 3e-90 48
pilR NP_952546.1 sigma-54-dependent transcriptional response regulator PilR BAC0467 Protein 5e-80 45

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
pilR NP_952546.1 sigma-54-dependent transcriptional response regulator PilR VFG0116 Protein 2e-65 46
pilR NP_952546.1 sigma-54-dependent transcriptional response regulator PilR VFG1214 Protein 9e-84 44