Gene Information

Name : kdsB (DVU3114)
Accession : YP_012325.1
Strain : Desulfovibrio vulgaris Hildenborough
Genome accession: NC_002937
Putative virulence/resistance : Virulence
Product : 3-deoxy-manno-octulosonate cytidylyltransferase
Function : -
COG functional category : M : Cell wall/membrane/envelope biogenesis
COG ID : COG1212
EC number : 2.7.7.38
Position : 3263483 - 3264241 bp
Length : 759 bp
Strand : -
Note : CMP-2-keto-3-deoxyoctulosonic acid synthetase; catalyzes the formation of CMP-3-deoxy-D-manno-octulosonate from CTP and 3-deoxy-D-manno-octulosonate which is incorporated into LPS

DNA sequence : 
ATGAGCGCACCCCGAACCTGCTACGGCATCATCCCAGCGCGCTACGCTTCGTCGCGCTTTCCGGGCAAGCCCCTTGCCGA
GATCTTGGGCAGGCCCATGTTCTGGCATGTCTACGACAGGGCACGGCGTTGTGCGGCCTTCGACGAGGTGGCCCTCGCCA
CCGACGACGCCCGCATCGCGGACGCCGCGAATGTACTCGGCGTCCCCTGTGTCATGACGGCGGAGCATCACCCGAGCGGC
ACCGACCGGGTACACGAGGCCGCCATGCGCCTCGGCGTGCCCGATGACGCGGTGGTGGTCAACATACAGGGTGATGAACC
GGCACTCGACCCGCGCATGCTCGACCAGCTTGTGGCCCCGTTCGCCGACGCATCGGTGCGCGTCGCCACGCTGGCCATGG
CCCTGTCAGCCCAAGAGGCGCAAAGCCCCGACAGGGTCAAGGTCGTGGTCGCCGCCAACGGCGATGCCCTCTATTTCTCG
CGGGCGGACATACCCTTCGTGCGCGACGGGGATGTCGGGGGCGATACCGCAGGGCGTCTCGGCCATATCGGGCTGTACGC
CTTCCGCATGGAGGCGCTGCGGCGTTTCACGCAGCTACCGCCTTCACGACTTGAACAGACTGAGAAACTCGAACAGCTGC
GGCTGCTCGAGAACGGTATAGCCATTCGTGTGGTGCCTACCACCTACCGTACCCACGGCGTGGACAGGCCCGAAGACATC
GACGTGATCATCAACCTGCTGAGGGAGAACGACGGATGA

Protein sequence : 
MSAPRTCYGIIPARYASSRFPGKPLAEILGRPMFWHVYDRARRCAAFDEVALATDDARIADAANVLGVPCVMTAEHHPSG
TDRVHEAAMRLGVPDDAVVVNIQGDEPALDPRMLDQLVAPFADASVRVATLAMALSAQEAQSPDRVKVVVAANGDALYFS
RADIPFVRDGDVGGDTAGRLGHIGLYAFRMEALRRFTQLPPSRLEQTEKLEQLRLLENGIAIRVVPTTYRTHGVDRPEDI
DVIINLLRENDG

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
kpsU AAZ04469.1 CMP-KDO synthetase Virulence PAI I APEC-O1 Protein 7e-42 45
kpsU YP_854332.1 3-deoxy-manno-octulosonate cytidylyltransferase Not tested PAI I APEC-O1 Protein 9e-42 45
kpsU CAE85213.1 KpsU protein Virulence PAI V 536 Protein 6e-42 44