Gene Information

Name : leuS (DVU1196)
Accession : YP_010415.1
Strain : Desulfovibrio vulgaris Hildenborough
Genome accession: NC_002937
Putative virulence/resistance : Unknown
Product : leucyl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0495
EC number : 6.1.1.4
Position : 1287085 - 1289574 bp
Length : 2490 bp
Strand : -
Note : leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl

DNA sequence :
ATGAAATACGATCATCAGTCCATCGAGACCCGGTGGCAGAAGAAGTGGGAAGACAGCGGCATCTTCCAGTGCGATACCGA
AGCCGACAAGCCCAAGTACTATGTGCTCGAGATGTTCCCCTACCCTTCGGGCAACATCCACATGGGGCACGTCCGCAACT
ATTCCATCGGCGACGTGGTGGCGCGCTTCAAGCGCATGCAGGGTTTCAACGTCCTTCACCCCATGGGATGGGACGCCTTC
GGCCTGCCCGCCGAGAACGCGGCCATCAAGAACGGCACCCACCCTGCAAAGTGGACGTTCGCCAACATCGACAACATGCG
CAGCCAGCTCAAACGGCTTGGCTACTCCTACGACTGGCAGCGCGAAGTGGCCACCTGCACACCCGAGTACTACAGGTGGG
AGCAGCTCTTCTTCTTGCGCTTCCTCGAGAAGGGTCTGGTCTACCGCAAGAAGGCGGCCCAGAACTGGTGCCCCAAGTGC
CACACCGTGCTCGCCAACGAGCAGGTCATCGAAGGACTGTGCTGGCGCTGTGACAGCGCAGTGGAACAGAAGGAACTCAC
CCAGTGGTTCCTGCGCATCACCGACTATGCCGAAGAGCTTCTGGCCGACCTTTCCAAGCTCGAGAACGGCTGGCCCGAGC
GCGTCCTCAGCATGCAGCGCAACTGGATTGGCAAGTCGACGGGTGCAGAGATACGTTTCGCGCTGGACGGGCGCGACGAC
TCCATCACCGTCTTCACCACGCGCCCCGACACCATCTTCGGTGCCACCTTCATGAGCATCGCCCCCGAGCATCCGCTCGT
GGAAGAGCTCATCGACGGCAAGCCGCAAGCTGATGACGTGCGAGCCTTCGTCGAGCGCATCCGCAACATGGACCGCATCG
ACCGCCAGTCCGACACCCTCGAAAAGGAGGGAGTGTTCACCGGTGCCTACTGTGTGAACCCCTTCACCGGCCGAAAGATG
CCCATATGGGTGGCCAACTTCGTTCTCGCCGAATACGGAACCGGGGCTGTCATGGCCGTTCCCGCCCATGACCAGCGCGA
CTTCGAATTCGCCCGCAAGTACGACCTGCCCATGCAGGTGGTCATCCAGCCCCAGGGCGAAGCGCTCGACCCCGCCACCA
TGTCTGCGGCATGGACCGAAGCCGGTGCGCTGGTCAATTCCGGCGCCTTCGACGGGCTTGCCAACGAAGACGCCAAGCAG
CGCATCGCCGACGACCTTGAGACCACCGGCAACGGACGCCGCACCATCAACTACCGCCTGCGCGACTGGAACATCTCGCG
CCAGCGTTACTGGGGTGCGCCCATTCCCGTCATCTACTGCGACGCCTGCGGCGTGGTGCCCGAGAAGGAAGAGAACCTTC
CCGTGGTGCTGCCGCTCGATGTGAAGACCCACGATGACGGTCGCTCGCCGCTGCCGCACACTCCGGCATTCTACGAGTGC
ACCTGCCCCGTATGCGGCGGCAAGGCACGGCGCGAGACGGACACCATGGACACCTTCGTCGAGTCGTCGTGGTACTTCGC
ACGGTACACCGACGCCACCAACGACAAGGCGCCCTTCACGCCTGACGCCCTGCGCTACTGGCTGCCCGTGGACCAGTACA
TCGGCGGTGTCGAACACGCCATCCTGCACCTGCTCTACTCCCGCTTCTTCACCAAGGCACTGCGCGACTGCGGCTTCATC
GAACTCGATGAACCCTTCGCCAACCTGCTCACGCAGGGCATGGTGCTCATGGATGGCAGCAAGATGTCCAAGTCGAAGGG
CAACGTCGTCGACCCCACGGAGATGATAGCCCGCTACGGCGCGGACACCGTGCGCCTCTTCTGCCTCTTCGCTGCACCGC
CGGAGCGCGACTTCGACTGGAGCGAGAGCGGCATCGAAGGTTCGTACCGCTTCGTGGGCCGTGTATGGCGTCTTGTCGAA
GAACTGCGCGAGCACCTTCTGGCTGTGGGCGCCTGTTCCAGCACCGCCGAGGACGCGAAGACACCCGTCGCGCGTGAACT
GCGGCTCAAGGAACATGCCACCGTCCGCAAGGCCGGTGACGACCTCAACGACAGGTTCCAGTTCAACACGGCCATCGCGG
CTGTCATGGAACTGGTCAACGCCCTGTATCTCGCCAAGGATGAACTCGTCGCAGACGAATCCGGTCGCAAGGTACTGTCT
TCCGCCGTGTCCACCGTGCTCACGCTGCTCTCTCCCTTCACGCCGCACCTTAGCGAGGAACTCTGGGCGCTTCTCGGCCA
CACCGAAAGCGTCAGCACCTTGCCGTGGCCGCGCTGGAAGGAGGATGCCCTCGTGCGCGATACGGTGACGCTGGTGGTGC
AGGTCAACGGCAAACTGCGCGGCAAGCTCGACATCCCCGCCGATGCGTCGCGCGAAGAGGTGGAGACCCTCGCCCTCAAC
GAACCCAACGTCCTCCGCTATCTGGAAGGCGTGACGGTGCGCAAGGTGGTGGTCATCCCCGGGAAACTCGTCAATGTGGT
CGTCAGCTAG

Protein sequence :
MKYDHQSIETRWQKKWEDSGIFQCDTEADKPKYYVLEMFPYPSGNIHMGHVRNYSIGDVVARFKRMQGFNVLHPMGWDAF
GLPAENAAIKNGTHPAKWTFANIDNMRSQLKRLGYSYDWQREVATCTPEYYRWEQLFFLRFLEKGLVYRKKAAQNWCPKC
HTVLANEQVIEGLCWRCDSAVEQKELTQWFLRITDYAEELLADLSKLENGWPERVLSMQRNWIGKSTGAEIRFALDGRDD
SITVFTTRPDTIFGATFMSIAPEHPLVEELIDGKPQADDVRAFVERIRNMDRIDRQSDTLEKEGVFTGAYCVNPFTGRKM
PIWVANFVLAEYGTGAVMAVPAHDQRDFEFARKYDLPMQVVIQPQGEALDPATMSAAWTEAGALVNSGAFDGLANEDAKQ
RIADDLETTGNGRRTINYRLRDWNISRQRYWGAPIPVIYCDACGVVPEKEENLPVVLPLDVKTHDDGRSPLPHTPAFYEC
TCPVCGGKARRETDTMDTFVESSWYFARYTDATNDKAPFTPDALRYWLPVDQYIGGVEHAILHLLYSRFFTKALRDCGFI
ELDEPFANLLTQGMVLMDGSKMSKSKGNVVDPTEMIARYGADTVRLFCLFAAPPERDFDWSESGIEGSYRFVGRVWRLVE
ELREHLLAVGACSSTAEDAKTPVARELRLKEHATVRKAGDDLNDRFQFNTAIAAVMELVNALYLAKDELVADESGRKVLS
SAVSTVLTLLSPFTPHLSEELWALLGHTESVSTLPWPRWKEDALVRDTVTLVVQVNGKLRGKLDIPADASREEVETLALN
EPNVLRYLEGVTVRKVVVIPGKLVNVVVS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
leuS YP_281511.2 leucyl-tRNA synthetase Not tested Not named Protein 4e-159 42