Gene Information

Name : guaA (DVU1043)
Accession : YP_010264.1
Strain : Desulfovibrio vulgaris Hildenborough
Genome accession: NC_002937
Putative virulence/resistance : Unknown
Product : GMP synthase
Function : -
COG functional category : F : Nucleotide transport and metabolism
COG ID : COG0519
EC number : 6.3.5.2
Position : 1145100 - 1146647 bp
Length : 1548 bp
Strand : -
Note : contains glutamine-hydrolyzing domain and glutamine amidotransferase; GMP-binding domain; functions to produce GMP from XMP in the IMP pathway

DNA sequence :
ATGGACGCACAGACCAAGGTCATCATCATCGACTACGGCTCGCAGGTTACGCAGCTCATCGCACGGCGCGTACGCGAAGC
CGGTGTCTACTCCGAGATACACCCCTGCATCGTCACCGCCGAGCAGGTACGGGCCATGAAGCCCGCCGCCATCATCCTTT
CCGGCGGCCCTGCCAGCGTCGGCGAGAAGGACGCACCCGCCCTCGAGAAGGGGCTGCTCGACCTTGGCGTGCCGGTGCTC
GGCATCTGCTACGGCATGCAGCTTCTGGGGCAGGACCTCGGCGGCGAGCTTGCCACCTCCGAGACCCGCGAATACGGGCC
TGCCGACCTCACCCTCACCGCCCCCTGCCCCCTGTGGGACGGTCTCGACCTCGGCACCACCTCGCGCGTGTGGATGTCCC
ATGGCGACAAGGTGAAGACGCCGCCCCCCGGCTTCAAGGTCGTGGGCCGTACCGCCACCCTCGAAGTGGCCGCCATGGCC
GACGAGGCCCGGCGCATCTACGCCGTCCAGTTTCATCCCGAAGTGCACCACTCCGAGGACGGGGCCCGCATCATCAACAA
CTTCCTCTTCCACGTGGCCAAGCTGAAGGCCGACTGGACCATGTCGTCGTTCGTCGAACGCGCCGTGAAGGAGATGGCCG
AAGTCGTGGGTGACAGGCATGTCGTCTGCGCCCTCTCCGGCGGCATCGACTCCACCGTGGTCGCCGTGCTGCTGCACAAG
GCCATAGGCAAGCAACTGCACTGCATCTTCGTTGACAACGGCGTGCTGCGCCTCAACGAGGGACAGGAAGTGGTCGACTA
CCTGCGCGAGCATTTCGACCTCAACCTCAAGTACGTGCAGGCACAGGAGCGTTTCCTCTCCAAGCTGCATGGCGTCGACG
ACCCCGAACAGAAGCGCAAGATCATCGGCTACACCTTCATCGAGGTGTTCGACGAAGAGGCCAAGGCCCTCGGACATGTC
GACTTCCTCGCGCAGGGCACGCTGTACCCCGACGTCATCGAATCGGTGTCGCACAAGGGTCCCTCTGCGGTCATCAAGAG
CCATCACAACGTGGGTGGTCTGCCCGAGAAGATGAACCTGAAGCTCATCGAACCGCTGCGCGAACTCTTCAAGGACGAGG
TCCGCAAGGTCGCCGCCGAACTGGGCCTGCCCGACTTCATCATCTGGCGTCACCCCTTCCCCGGCCCGGGGCTTGCCATC
CGGGTCATCGGCGAGATAACCGAAGAGAGGCTCGACATCCTCCGCCGTGCCGACAAGGTCGTGCAGCAGGAACTCATGTC
CTCCGGCTGGTACCGCAAGGTGTGGCAGGGCTTCGCCGTGCTGCTGCCGCTCAAGACCGTGGGCGTCATGGGTGACGGGC
GTACTTACGAACACGTCATCGCCCTGCGCATCGTCGACAGCGTCGATGCCATGACCGCCGACTGGGCACGCTTGCCTTCC
GAACTGCTTGAGCGTATCTCCAGCCGGATAATCAACGAAGTCAAGGGCGTGAACCGGGTGGTCTACGACATCTCGTCCAA
GCCCCCGAGCACCATAGAATGGGAGTAA

Protein sequence :
MDAQTKVIIIDYGSQVTQLIARRVREAGVYSEIHPCIVTAEQVRAMKPAAIILSGGPASVGEKDAPALEKGLLDLGVPVL
GICYGMQLLGQDLGGELATSETREYGPADLTLTAPCPLWDGLDLGTTSRVWMSHGDKVKTPPPGFKVVGRTATLEVAAMA
DEARRIYAVQFHPEVHHSEDGARIINNFLFHVAKLKADWTMSSFVERAVKEMAEVVGDRHVVCALSGGIDSTVVAVLLHK
AIGKQLHCIFVDNGVLRLNEGQEVVDYLREHFDLNLKYVQAQERFLSKLHGVDDPEQKRKIIGYTFIEVFDEEAKALGHV
DFLAQGTLYPDVIESVSHKGPSAVIKSHHNVGGLPEKMNLKLIEPLRELFKDEVRKVAAELGLPDFIIWRHPFPGPGLAI
RVIGEITEERLDILRRADKVVQQELMSSGWYRKVWQGFAVLLPLKTVGVMGDGRTYEHVIALRIVDSVDAMTADWARLPS
ELLERISSRIINEVKGVNRVVYDISSKPPSTIEWE

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
SAPIG0468 YP_005733278.1 GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) Not tested SAPI-S0385 Protein 4e-137 55
SAMSHR1132_03620 YP_005324884.1 GMP synthase Not tested vSa¥á Protein 4e-137 55
guaA YP_001331415.1 GMP synthase Not tested vSa¥á Protein 5e-137 54
guaA NP_938969.1 GMP synthase Not tested Not named Protein 2e-124 50