Gene Information

Name : serS (DET0577)
Accession : YP_181319.1
Strain : Dehalococcoides ethenogenes 195
Genome accession: NC_002936
Putative virulence/resistance : Unknown
Product : seryl-tRNA synthetase
Function : -
COG functional category : J : Translation, ribosomal structure and biogenesis
COG ID : COG0172
EC number : 6.1.1.11
Position : 529182 - 530423 bp
Length : 1242 bp
Strand : -
Note : catalyzes a two-step reaction, first charging a serine molecule by linking its carboxyl group to the alpha-phosphate of ATP, followed by transfer of the aminoacyl-adenylate to its tRNA

DNA sequence :
ATGCTTGATTTGAAATTTATAAGAGAAAATACCGAACTAGTACGCAAAGCGGTAGCCGCCCGTAATACCGATGCCCCCAT
TGATGAGATACTGGAGCTGGATAGTTGCCGCCGCACTCTCAGCCAGGAGCTGGATACCCTTCGCGCCAAACGCAAAATAA
TAGCCAAGCAGCGGGATGAGGCCGCCATTGAAGAAGGGCGGGTATTACGCGGCAGGATAAGTGAACTTGAGACCGGGCTT
TCAGAAGTAGAGGAAAAGCTGACTGACCGCTTGCTCAGGGTACCCAATATCCCGGATGCATCTGTACCTGTGGGCAAAGA
CGAAAGCGAAAACGTAGTCCTTTATTACCGGGGAGAAAAACGTAATTTCAGCTTTACCCCCAAACCCCACTGGGAACTGG
GAGAAGCGCTGGATATTATAGATTTTGACCGGGGTATCAAGCTTTCCGGTTCACGCTTTTATATTTTGAAGGGTGAGGGC
GCGCGCCTTCAAAGGGCACTTATTGCCTTTATGCTGGACCTGCACACCCGCAAACACGGCTATACCGAAATCTACCCGCC
CTACATGATAAAAAGGGAGTGTCTGGTAGCGTCTGGTAACCTGCCCAAATTTGCTGACAATTTGTACCATGACGCAGAGG
AGGACTACTGGTGGGTGCCTACCGCCGAAGCCCCTCTGACTAATTTGCACCGTGACGAAATACTTTCTGTTGAGCAGCTG
CCCATTCATTACGTAGCCTACACCGCCTGTTTCCGCCGCGAAAAAATGTCTGCCGGCAAAGATGTACGCGGTATAAAACG
GCTGCACCAGTTTGACAAGGTTGAACTGTATAAATACTGCAAACCGGAAGACTCTTTTGACGAACTGGAAAAGATGGTGG
CAGATGCTGAAGAAATAGCAGACGCCCTAAAGATACCCTACCGCTTAAAACAGCTGGTTACGGCTGATATCAGTTTCGGT
TCAGCCAAGTCTTATGATATTGAAATGTATTCGCCGGGTGTTGACGAGTGGCTGGAAGTTTCTTCCTGTTCTAACTGCAC
AGATTTTCAGGGCAGGCGGGCTAATGTCCGTTTCCGCCGCACCCCCGAAGCCAAACCCGAATTTGTCCACACCTTAAACG
GCTCCGGGCTGGCCCTGCCCAGGGTGATGATATCGGTTATAGAAAACTACCAGCTGCCGGACGGAAGCATTGTTGTTCCC
GAAGTACTCCGCCCCTTTATGGGAGTGGATGCTATCTGCTAA

Protein sequence :
MLDLKFIRENTELVRKAVAARNTDAPIDEILELDSCRRTLSQELDTLRAKRKIIAKQRDEAAIEEGRVLRGRISELETGL
SEVEEKLTDRLLRVPNIPDASVPVGKDESENVVLYYRGEKRNFSFTPKPHWELGEALDIIDFDRGIKLSGSRFYILKGEG
ARLQRALIAFMLDLHTRKHGYTEIYPPYMIKRECLVASGNLPKFADNLYHDAEEDYWWVPTAEAPLTNLHRDEILSVEQL
PIHYVAYTACFRREKMSAGKDVRGIKRLHQFDKVELYKYCKPEDSFDELEKMVADAEEIADALKIPYRLKQLVTADISFG
SAKSYDIEMYSPGVDEWLEVSSCSNCTDFQGRRANVRFRRTPEAKPEFVHTLNGSGLALPRVMISVIENYQLPDGSIVVP
EVLRPFMGVDAIC

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
serS YP_003446791.1 seryl-tRNA synthetase Not tested The aminoglycoside resistance gene cluster Protein 2e-92 46