Gene Information

Name : clpC (DET0057)
Accession : YP_180810.1
Strain : Dehalococcoides ethenogenes 195
Genome accession: NC_002936
Putative virulence/resistance : Virulence
Product : ATP-dependent Clp protease, ATP-binding subunit ClpC
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0542
EC number : -
Position : 51068 - 53542 bp
Length : 2475 bp
Strand : +
Note : identified by similarity to SP:P37571; match to protein family HMM PF00004; match to protein family HMM PF02861

DNA sequence :
ATGTCTAGCAGATTTGATAAATTTTCTGAAAGAGCGCGCCGGGTTCTTACCTATGCACAGGAGGAAGCCCAAAGCCTTAA
CCATAACTATATCGGCACTGAGCATATTCTGCTGGGGCTGGTTAGGGAAGAAGAAGGCGTGGCCGCCCGCGTACTGGTGA
ATATGGACGTAAACCTGGCCAAGGTACGTTCGGCTGTTGAGTTTATACTGGGGCGGGGCGAACACCCGGCCACCTCTGAA
ACTGGTCTTACCTCCAGAGCCAAAAAGGTAATAGAACTGGGCATTGATGAGGCCCGGAATCTGGGTCACAACTATATCGG
CACTGAACACCTGCTTTTAGGTTTACTGCGTGAAGGCGAAGGGGCGGCTGCCGGTGTCCTTGAGAGTTTCGGGGTTACTG
TTGAAAAGGTACGCACCGAAGTAGGGCGTATTTTGAATCAGGGCTTAAATAAACCTAAAGCCGGCCGGGCAACTCCCAGC
CGCACTCCCCAGCTTGACCAGCTGGGCTTTGACCTGACGGCCGCTGCCAGAACCGGCAAACTTGACCCGGTTATCGGGCG
TGCCAAAGAAATAGAGCGGGTTGTCCAGATTCTTTCCCGCCGTACCAAAAATAACCCTGCCCTTATCGGCGAACCCGGTG
TCGGCAAAACCTCCATTGTGGAGGGGCTGGCCCAGCGGATTGTTTCGGGTGACGTGCCGGAAACTCTGGAACAGAAACAT
ATAATTTCGCTGGACGTGGCCTCACTGGTAGCCGGTACTAAATACCGGGGTGAATTTGAAGAACGGCTCAAGAAAGTTAT
TGAAGAGATTAAAACCGCAGGTAATATAATCCTGTTTATAGACGAATTCCATACCATGGTGGGTGCCGGTGCCGCCGAGG
GTGCGGTAGATGCCGCCAATATCCTCAAGCCTTCGCTGGCCAGAGGTGAGGTACAGGTAATAGGGGCAACCACCCTGGAT
GACTTCCGCAAATATGTTGAGCGGGATGCCGCATTTGAGCGGCGTTTCCAGCCGGTGCTGGTGGAAGAACCGGCCATAGA
AGATACCCTGAGTATACTTCGGGGCATAAAAGAGCGCTACGAAGAGCATCATAAGCTTATCATCAGCGAAGAAGCTATTG
TCGCTGCCGCCAATATGGCTGCCAGATATATACCTGACCGCTTTTTGCCGGATAAGGCTATAGATTTAGTTGATGAAGCC
GCTTCACGGGTGCGGATAAAGAAACGCACCAAGCCGGTCTCTTTGAAAGAGATGAAAGCCATAGAAGACAGCTACCGCCG
GGATAAAGAAGCCGCTTTGGCTACCCAGCAGTATGATTATGCCTCCGAATTGCGTGAGCGTGAGCTTCAGATAGCTGAAA
AGATACGCCGCATGGAAGACGAATGGCAGAACGAACAGGCCATGGATAAGCCGGTGGTGGGCGAAGAAGATATTGCCCAG
GTAGTCAGCATGTGGACGGGTGTGCCGCTGGTACAGCTTACCGGTGACGAAACCGAACGTCTTTTACATATGGAAGAAGC
CCTGCATGAGCGGATTATCGGCCAGGAAGAGGCCATTGTTACCATATCCAAGGCTGTCAGACGGGCACGGGCAGGTCTTA
AAGATCCCCGCCATCCCATCGGCAACTTTGTCTTCCTGGGGCCCACCGGCGTAGGTAAAACCGAGCTGGCACGGGCGCTT
GCCCAGTTTATGTTCGGTTCAGAAGACGCTTTAGTGCGGCTGGATATGTCCGAATTTATGGAAAAGTTTGCCGTATCCCG
TCTGGTGGGTGCGCCCCCCGGATATGTGGGCTATGACGAGGGCGGCCAGTTGACTGAAGCTGTTCGCCGCAAGTCTTATT
GCCTGATACTGCTGGACGAAATAGAAAAAGCTCATCCTGACGTTTTCAATATTCTTCTGCAGATATTTGATGACGGCCAC
CTGACAGATACCAAGGGCAGACGGGTGGACTTTCGGAATACCATTATTATTATGACCTCAAACATCGGGGCGGAGCTTAT
CCGCAAGGGCAGCGGAACTATCGGTTTTGCTACCCAGACAGATGAATCAAAGGCTCAGCAGACCAACTTTGAGCATATGA
AAGACAAGCTGCTGGGTGAGCTTAAGAAGAGCTTCCGCCCGGAGTTCCTGAACCGTATTGACAGTGTGGTGGTCTTCCAC
TCACTTAATAAAGAGCAGATTCGCAGTATTGTTGACCTGATGCTTAAGAGTGTTATCAAGCAGATGTCTGAAAAGGGTAT
CGGGCTTGAAGTGACTGACTCTGCCAAAGACTTGCTGGGCAAGAAGGGTTATGACGAGGTTTATGGTGCAAGGCCGCTGC
GCCGCACTATCCAGACCATGCTGGAGGACAGGCTGTCCGAGGACCTGCTGCGGGCTAAATTTGAAGCCGGGGATAAAGTG
ATAGTGGATACTGCCGAAGACGAAATAATTGTCCGTCTGGCAGAGCCGGCCGAACTTAGCCAGGCCACTTCATAA

Protein sequence :
MSSRFDKFSERARRVLTYAQEEAQSLNHNYIGTEHILLGLVREEEGVAARVLVNMDVNLAKVRSAVEFILGRGEHPATSE
TGLTSRAKKVIELGIDEARNLGHNYIGTEHLLLGLLREGEGAAAGVLESFGVTVEKVRTEVGRILNQGLNKPKAGRATPS
RTPQLDQLGFDLTAAARTGKLDPVIGRAKEIERVVQILSRRTKNNPALIGEPGVGKTSIVEGLAQRIVSGDVPETLEQKH
IISLDVASLVAGTKYRGEFEERLKKVIEEIKTAGNIILFIDEFHTMVGAGAAEGAVDAANILKPSLARGEVQVIGATTLD
DFRKYVERDAAFERRFQPVLVEEPAIEDTLSILRGIKERYEEHHKLIISEEAIVAAANMAARYIPDRFLPDKAIDLVDEA
ASRVRIKKRTKPVSLKEMKAIEDSYRRDKEAALATQQYDYASELRERELQIAEKIRRMEDEWQNEQAMDKPVVGEEDIAQ
VVSMWTGVPLVQLTGDETERLLHMEEALHERIIGQEEAIVTISKAVRRARAGLKDPRHPIGNFVFLGPTGVGKTELARAL
AQFMFGSEDALVRLDMSEFMEKFAVSRLVGAPPGYVGYDEGGQLTEAVRRKSYCLILLDEIEKAHPDVFNILLQIFDDGH
LTDTKGRRVDFRNTIIIMTSNIGAELIRKGSGTIGFATQTDESKAQQTNFEHMKDKLLGELKKSFRPEFLNRIDSVVVFH
SLNKEQIRSIVDLMLKSVIKQMSEKGIGLEVTDSAKDLLGKKGYDEVYGARPLRRTIQTMLEDRLSEDLLRAKFEAGDKV
IVDTAEDEIIVRLAEPAELSQATS

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
clpC YP_005163377.1 ATP-dependent Clp protease ATP-binding subunit Not tested Not named Protein 0.0 55

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
clpC YP_180810.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0079 Protein 0.0 57
clpC YP_180810.1 ATP-dependent Clp protease, ATP-binding subunit ClpC VFG0080 Protein 4e-148 50