Gene Information

Name : smpB (DET1506)
Accession : YP_182206.1
Strain : Dehalococcoides ethenogenes 195
Genome accession: NC_002936
Putative virulence/resistance : Unknown
Product : SsrA-binding protein
Function : -
COG functional category : O : Posttranslational modification, protein turnover, chaperones
COG ID : COG0691
EC number : -
Position : 1361164 - 1361682 bp
Length : 519 bp
Strand : +
Note : binds to ssrA RNA (tmRNA) and is required for its successful binding to ribosomes; also appears to function in the trans-translation step by promoting accommodation of tmRNA into the ribosomal A site; SmpB protects the tmRNA from RNase R degradation in Ca

DNA sequence :
ATGCATTATGCCCGGATTGTAAGCAATCTGCATCTGGGGTATGATATAATACATATGGCAGAATACGTAACCCTGACAAC
TAACCGCAAGGCATTTCACAACTATTTCCTGGAAGAAAAATACGAAGCCGGGATAATGCTGCTGGGCACGGAGATAAAAT
CCCTCCGAAGCGGCAGAGTAAATATGGGAGATGCCTATGTAAAGCCCCAGAGGGGCGAACTCTGGCTGGTAAATGCCCAT
ATTTCAGCCTACGAGTGCAGCGGACATACCAGCCATGAACCAATGCGGGAACGCAAACTGCTGATGCACCGCAAGGAAAT
AGCCCTGCTCATGTCAAAGGTCAAAGAAAAAGGGCTGACACTGATACCGGTTCGTATTTACCTAAAAAACGATATCGCCA
AGGTAGAGCTGTCACTGGGGCGGGGTAAGAAGCTCTATGACAAAAGGGATACCATAACCAAGCGGGACACCGAACGCGAA
CTTGAGCGGGAGGTCAAATACCGCAATTTCCGCCGCTAG

Protein sequence :
MHYARIVSNLHLGYDIIHMAEYVTLTTNRKAFHNYFLEEKYEAGIMLLGTEIKSLRSGRVNMGDAYVKPQRGELWLVNAH
ISAYECSGHTSHEPMRERKLLMHRKEIALLMSKVKEKGLTLIPVRIYLKNDIAKVELSLGRGKKLYDKRDTITKRDTERE
LEREVKYRNFRR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
unnamed AET14351.1 SsrA-binding protein Not tested SaPI68111 Protein 3e-28 45
smpB YP_001800894.1 SsrA-binding protein Not tested Not named Protein 3e-28 45