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Name : DIP0753 (DIP0753) Accession : NP_939126.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Resistance Product : lantibiotic modifying enzyme Function : - COG functional category : V : Defense mechanisms COG ID : COG4403 EC number : - Position : 729107 - 732040 bp Length : 2934 bp Strand : + Note : Similar to Staphylococcus aureus lantibiotic modifying enzyme TR:Q9S4D1 (EMBL:AF147744) (965 aa) fasta scores: E(): 5.3e-32, 21.471% id in 1006 aa, and to Lactococcus lactis Plasmid pMRC01 lacticin 481/lactococcin biosynthesis protein LcnDR2 TR:O87238 (EM DNA sequence : GTGCTTGTGGGTAGCATTAGGAAATTTTTCCCAGAGATCACAGATGATCTGTTCCAAGAACTATTGACTAGTGCTGCCTA CGAGCACGGTGTGGCCTCGCTCCAAGGAGAGATCGAAAAATTCACACAAAAGAACAGTGAGACTGACGAAGAGGTGCTCG CTGACAATCTTGCAGAACTCTACCGATTCTTCGAACGCGAACCTATCCCCTTCCTTGATTCAACATGGGCACTATCCGAC TTGCAAATATCATCCATCAGGGACGTGATTGATGCTTTTCCTCACAGAATCGACTGCGACGCTGTAATTAAATCATTCGT ATCTGCAAATTGTTCAGCACTTCAACGCCTTCTTCTGAGATGTCAACTCGAGTTCGTTGAAAAGGAAATAAGTAGCAACG GACCAGAACTGACTTATGAAGAGTCCTCTCAAGCACTTTTCCGAAGCTTGGCACAATTTAAGGAACGCTATCCAATTGCG TGGTACCTGGCAAACCGTAAGTGTGAACGCAGTTTAAGGTACCTGTCAGAGATACTAGACCATTTGAAGGAAGACTGGTC TAGACTGTCAAGGTTCGGACTGACAGAGGACTCACAAGTATCAAACATCACCTTTGAACTGGGTGATACGCATGATGGCA AAAGCGTTGCAGTTGTGACCTTGGATGATGGACAACAGATTTTTCACAAACCGCGACCTCTAGATGTAGAGGAGTCTTGC TCGAGGTTTGCCGAGCAGTTGGGCCGAATGTTTGGATTTACCTGCCCGTTCGTCGGAAAGGTAATCACTCGGGGCTCATA CGGCTGGGCAGAGCATGTCCCACACGTCGAAGAAAGCCGCTTTGATAATCCAAGGGCAGCAGCCGAGTTTGCCCTACTCC TGAAGCTTCTAAGTTTTACCGATGTTCATTACGAGAACGTGCGCTTTAGCGCCGATGGTATCCCAATCCTGGTAGACGCT GAGACCGCCCTTACCTCGGGTCTCTGTCGTCGTGACAGTGAGGGTATACCAATACACGCTGCACTATCCGAGACTGTCAC CTCAACAGGCTTTTTCCCGTCACCGCTAGTTATCCCCAAAAAGCGCGGAGAAACTTTTGTAGATGTTGGCGTACTTGGTA GACGCGATAAGAACCTTATTACTGAGCGCCAGCTAGTATTAAAGAATCCTTTTACAAATAAGATGCACTTGGTGTATGAG GATGTAGCCAAGCATATGTCTGATAACGCGTCTAGTTTCCGTTTTTCATCCGACTACGTCAGAAGTTTAACAGAACGCTA CAGAGAACTTACTAAAGCTGTCGTTGACAAAAAGGCATCGATCTCTAACTTGTTACGAGAGTGCTTTTCTAAGTCGTGTT TTCGTGTAGTGGTGCAGGACACCATAAAATACGTTAATGCTATTCAGCTGGCAACAAATCAGCAGTGTCTAAGTAGTCCT AGTCTTTATGTTGGAGCCCTGCTACGCTTTGCTATTGGGCGTTTCGACAGTGACCGGCTACTATTGCGTAACGAGCTTGC AAGCCTCATTTCTGGAGATATTCCTCGATATGTGGTCTCAGCAACATCGAGTGACCTCGAAGGGTCTGTTCAAACAGTCA AAAAGAACTACTTTATCGAGTCGCCCATCGAAAATGCAATAGGTTGTGTGCAAAAGATGGATTCCAAAACCATTGAGCTG GACTGCTGGCTAATCGAGATTTCATTCGCGAGTTATTATGATGAATCATCCAATGCCACACAGTTTAAATATTCCGACAG CCTTTTTAACGTTTCACATAATATCGAAGTGTCACTAAATGAGGCACTTACATCTTTGTTGAATGGGTATGTTTACGGTT CAGGAAGTGCCCCGGCTACTTGGATTGGCGCTAGACTGAGCAACCAGGCTCATCAGTACTGGTACGTCGACGAAGTCTCC ATGGATCTATATGCCGGATCCTCCGGCTTGGCTTTACCGCTTGTGTTGTCGGGGCCTGCGGGTCTTTCCTGTCGAGGAAG AAAAGAGGCACATGACTACTTTGATGGACTAGTCACCAAGCTTGAATCTCTAGATACCACACAGTTGGCTACGCTAAATA CGGGAGCCTTGTCTGGTGCGCACTCTGTGTTGTGGTCATTGCATTGTCATTATTCCGCCGCGGGGGATAACGGTGGACTC GAGCGACTAAAGTCACTAGCCAATAAAATGATTTCGTGTGCCTCGCACGACGGATTCGATTTCACTGGAGGCACTATCGG TTTATCGGTTTTGGCAAAGGCCTTAGGTGTATTCGAATCAACCAAAATTGAAGATGACTATTTAAATGCTCTAGACAGTT TGGCTGAATCGACCTCGCGTGGTTGTAGTTGGTTATCCGGCTATGCACATGGTCATGCCGGTGCTTTAGCCTCCGCTGCT ATGCTCTGCGACCACATTTCGAATAGGGATCGGCTCGAGAGCTCAGTAAGTAGATTGTTTAGTCAGTTCTTGAGTTTCCG TGAGAGTGAATCGAGATTATGGCCAATCGGCTTTGAACAAACTGGCATCGGTAGAGGTTGGTGTTCTGGTACTCCAGGTG TCCTTTTAGCGTTAGCTCAATTCCACGAGAGCGAGTTGGGAAAATGTTATGAGCTTGCTCCCACGATTGAATTTCTCACC GATGTAGTTAAGAAGGAAACCTTCGGCGGTAATCCCACATTGTGCCATGGGGACGTGGGCAATCTCTGGATTCTACAGAA GGTTGGTGAGTTGATAGGGGACCATGCCTTGGTTACAAGAAGTCGCGAGGCCGGCCTCTTCTGGCTCCAAAACGTTCTCC CTAGTTTTCTACGGTCGCTTTCAAGATTTTCGATTTCACACAGCTTCTTCGCTGGAATTGCTGGAACAGCGCTATATGGA GAGTACCTGTTGTCGTCTGAGGAAGTTGTGAGGTGTCCGCTATGGTTAGAGTGA Protein sequence : MLVGSIRKFFPEITDDLFQELLTSAAYEHGVASLQGEIEKFTQKNSETDEEVLADNLAELYRFFEREPIPFLDSTWALSD LQISSIRDVIDAFPHRIDCDAVIKSFVSANCSALQRLLLRCQLEFVEKEISSNGPELTYEESSQALFRSLAQFKERYPIA WYLANRKCERSLRYLSEILDHLKEDWSRLSRFGLTEDSQVSNITFELGDTHDGKSVAVVTLDDGQQIFHKPRPLDVEESC SRFAEQLGRMFGFTCPFVGKVITRGSYGWAEHVPHVEESRFDNPRAAAEFALLLKLLSFTDVHYENVRFSADGIPILVDA ETALTSGLCRRDSEGIPIHAALSETVTSTGFFPSPLVIPKKRGETFVDVGVLGRRDKNLITERQLVLKNPFTNKMHLVYE DVAKHMSDNASSFRFSSDYVRSLTERYRELTKAVVDKKASISNLLRECFSKSCFRVVVQDTIKYVNAIQLATNQQCLSSP SLYVGALLRFAIGRFDSDRLLLRNELASLISGDIPRYVVSATSSDLEGSVQTVKKNYFIESPIENAIGCVQKMDSKTIEL DCWLIEISFASYYDESSNATQFKYSDSLFNVSHNIEVSLNEALTSLLNGYVYGSGSAPATWIGARLSNQAHQYWYVDEVS MDLYAGSSGLALPLVLSGPAGLSCRGRKEAHDYFDGLVTKLESLDTTQLATLNTGALSGAHSVLWSLHCHYSAAGDNGGL ERLKSLANKMISCASHDGFDFTGGTIGLSVLAKALGVFESTKIEDDYLNALDSLAESTSRGCSWLSGYAHGHAGALASAA MLCDHISNRDRLESSVSRLFSQFLSFRESESRLWPIGFEQTGIGRGWCSGTPGVLLALAQFHESELGKCYELAPTIEFLT DVVKKETFGGNPTLCHGDVGNLWILQKVGELIGDHALVTRSREAGLFWLQNVLPSFLRSLSRFSISHSFFAGIAGTALYG EYLLSSEEVVRCPLWLE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| DIP0753 | NP_939126.1 | lantibiotic modifying enzyme | Not tested | Not named | Protein | 0.0 | 100 |
