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Name : mtrA2 (DIP0694) Accession : NP_939068.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Virulence Product : two component system response regulator Function : - COG functional category : T : Signal transduction mechanisms COG ID : COG0745 EC number : - Position : 668619 - 669317 bp Length : 699 bp Strand : + Note : Similar to Mycobacterium tuberculosis MtrA protein or Rv3246c or MTCY20B11.21c TR:Q50447 (EMBL:Z95121) (228 aa) fasta scores: E(): 7.6e-61, 70.66% id in 225 aa, and to Streptomyces coelicolor transcriptional regulatory protein AfsQ1 or 2SCK8.33c SW:AFQ1_S DNA sequence : ATGGAAAGGACCACGGACGGTATGGCACCGAAAATTTTGGTTGTCGACGATGATCCCGCGATTTCAGAGATGCTGACCAT CGTGCTGGAGGCCGAGGGATTTGAGCCGGTCGCGGTCACTGATGGGGCAGTAGCAGTTGATGCCTTTAGGACAGAATCGC CTGATCTAGTCCTACTCGATTTGATGCTGCCTGGTATGAATGGCATCGACATTTGTAGGATAATCCGGCAGGAATCGGCA GTTCCTATCGTCATGCTCACGGCGAAAACCGACACCGTGGACGTAGTCCTTGGTTTGGAATCAGGTGCAGATGACTACAT CAACAAGCCGTTTAAGCCGAAAGAACTCATCGCTCGACTACGTGCACGCTTGCGTCGTACAGAGGACTCTCCGTCCGAAA CCATTGAGATCGGGGATCTTACGATCGACGTCCTAGGCCACGAAGTCACTCGAGGAGATGAGGAAATTCAACTCACTCCT TTAGAGTTTGATTTGCTGCTTGAGCTTGCAAGCAAACCAGGACAGGTGTTCACACGTGAGGAACTTCTGCAAAAAGTTTG GGGCTACCGTAATGCCTCAGACACGAGACTGGTGAATGTCCATGTGCAGCGACTGCGCTCAAAGATCGAGAAAGACCCAG AAAACCCGCACATCGTGTTAACAGTGCGCGGAGTGGGGTATAAGACAGGGCAGGAGTAG Protein sequence : MERTTDGMAPKILVVDDDPAISEMLTIVLEAEGFEPVAVTDGAVAVDAFRTESPDLVLLDLMLPGMNGIDICRIIRQESA VPIVMLTAKTDTVDVVLGLESGADDYINKPFKPKELIARLRARLRRTEDSPSETIEIGDLTIDVLGHEVTRGDEEIQLTP LEFDLLLELASKPGQVFTREELLQKVWGYRNASDTRLVNVHVQRLRSKIEKDPENPHIVLTVRGVGYKTGQE |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| unnamed | CAD42044.1 | hypothetical protein | Not tested | PAI II 536 | Protein | 3e-31 | 44 |
| c3565 | NP_755440.1 | response regulator | Not tested | PAI I CFT073 | Protein | 2e-31 | 44 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| mtrA2 | NP_939068.1 | two component system response regulator | AE000516.2.gene3505. | Protein | 2e-63 | 71 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_012469.1.7685629. | Protein | 3e-36 | 48 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002952.2859905.p0 | Protein | 3e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_013450.8614421.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_007793.3914279.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_007622.3794472.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002745.1124361.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_009782.5559369.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002951.3237708.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_003923.1003749.p0 | Protein | 1e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002758.1121668.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_009641.5332272.p0 | Protein | 2e-36 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | HE999704.1.gene2815. | Protein | 9e-35 | 47 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_012469.1.7686381. | Protein | 3e-32 | 44 |
| mtrA2 | NP_939068.1 | two component system response regulator | CP000675.2.gene1535. | Protein | 3e-26 | 42 |
| mtrA2 | NP_939068.1 | two component system response regulator | AF155139.2.orf0.gene | Protein | 7e-28 | 42 |
| mtrA2 | NP_939068.1 | two component system response regulator | BAC0125 | Protein | 2e-25 | 42 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_010079.5776364.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002952.2859858.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_007622.3794948.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_003923.1003417.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_013450.8614146.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002951.3238224.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_007793.3914065.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | NC_002758.1121390.p0 | Protein | 1e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | HE999704.1.gene1528. | Protein | 5e-27 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | BAC0111 | Protein | 9e-21 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | AE016830.1.gene1681. | Protein | 6e-33 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | BAC0083 | Protein | 5e-21 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | CP000034.1.gene3671. | Protein | 3e-28 | 41 |
| mtrA2 | NP_939068.1 | two component system response regulator | CP001918.1.gene5135. | Protein | 1e-14 | 41 |
| Gene | GenBank Accn | Product | ID of source DB | Alignment Type | E-val | Identity |
| mtrA2 | NP_939068.1 | two component system response regulator | VFG1563 | Protein | 2e-31 | 44 |
| mtrA2 | NP_939068.1 | two component system response regulator | VFG1702 | Protein | 7e-32 | 44 |
| mtrA2 | NP_939068.1 | two component system response regulator | VFG1390 | Protein | 1e-26 | 43 |
| mtrA2 | NP_939068.1 | two component system response regulator | VFG1389 | Protein | 9e-20 | 41 |
