Gene Information

Name : DIP0585 (DIP0585)
Accession : NP_938961.1
Strain : Corynebacterium diphtheriae NCTC13129
Genome accession: NC_002935
Putative virulence/resistance : Virulence
Product : iron ABC transporter ATP-binding protein
Function : -
COG functional category : P : Inorganic ion transport and metabolism
COG ID : COG1120
EC number : -
Position : 553311 - 554123 bp
Length : 813 bp
Strand : +
Note : Similar to Bacillus subtilis ferrichrome transport ATP-binding protein FhuC SW:FHUC_BACSU (P49938) (269 aa) fasta scores: E(): 1.2e-37, 45.13% id in 257 aa, and to Escherichia coli iron FecE or B4287 SW:FECE_ECOLI (P15031) (255 aa) fasta scores: E(): 5e-3

DNA sequence : 
ATGGACCGTAATTCCACAGCAACAATGCCGCAACAGTCCTTGGGCTGTATGTCGATGTCTGCAGGGTACGGGGCAGAATT
GATTGTTCGAGATGTTTCGCTCGACGTTCCAGCGGGCAAGATTACCGCGTTGATCGGGCCAAACGGTAGCGGAAAGTCGA
CCCTGCTGAAGGTGCTTGGCAGGCAGCTGCGTGCAGAAAGCGGCCAGGTGACGTTGGATGGCCGAGATATTGCGGATTTT
GGTGCGCGGGAGTTCGCACGGAATCTTGCATTCCTTCCGCAACAGCCGGTGGTACCAGACGGCATGACGGTGCGTGAGCT
TATTTCTTTTGGACGCTATCCATATTCGGGCGCGTTTGCGTCGTTAAGCGCGGCAGATCATGCTGCCATTGAGCGGGCTG
CTGCGGCGACGAGTATCACTGAGTTTTTGGACGCCGATGCCATGGCATTGTCCGGTGGGCAAAAACAACGCATGTGGATC
GCGGTCACGCTGGCGCAAGAAACCGGAATTTTGCTTCTCGACGAACCCACGACCTTCCTTGATCCTGCGCATCAATTGGC
GATTCTTGATCTGGTTCATGAGCTGAATCAGCAAGGCCGCACGATTGTGATGGTGTTGCATGATATGGCGCATGCGGCAA
AGTATTCCGACCATGTGGTGGTGATGAAAAATGGGGAAGTTTTGCAGCAAGGGCCAACGCAGTCAACGTTGAATTCTGGG
CTGATTGAGCAGGCTTTTGGTATTTCTACCATGATGGTGACCGATCCAGAGACGAATCGCCAACTTCCGATTGCCTATGG
CATCAAACGATAG

Protein sequence : 
MDRNSTATMPQQSLGCMSMSAGYGAELIVRDVSLDVPAGKITALIGPNGSGKSTLLKVLGRQLRAESGQVTLDGRDIADF
GAREFARNLAFLPQQPVVPDGMTVRELISFGRYPYSGAFASLSAADHAAIERAAAATSITEFLDADAMALSGGQKQRMWI
AVTLAQETGILLLDEPTTFLDPAHQLAILDLVHELNQQGRTIVMVLHDMAHAAKYSDHVVVMKNGEVLQQGPTQSTLNSG
LIEQAFGISTMMVTDPETNRQLPIAYGIKR

• Homologs from PAI DB

GeneGenBank Accn Product Virulance or Resistance PAI or REI Alignment Type E-val Identity
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 2e-115 100
ciuD YP_005685432.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-91 70
ciuD YP_005681255.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-91 70
ciuD YP_005683346.1 Iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-91 70
ciuD YP_003783391.1 iron ABC transporter ATP-binding protein Virulence PiCp 4 Protein 3e-91 70
fecE AAL08451.1 ATP-binding protein FecE Virulence SRL Protein 4e-47 43
iusE YP_005143742.1 iron ABC transporter ATP-binding protein Virulence Not named Protein 3e-45 43
fagC YP_005680307.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-45 42
fagC YP_005682397.1 ATP binding cytoplasmic membrane protein Virulence PiCp 1 Protein 5e-45 42
fagC YP_003782430.1 ABC transporter ATP-binding protein Not tested PiCp 1 Protein 5e-45 42
fagC YP_005684488.1 ATP binding cytoplasmic membrane protein Not tested PiCp 1 Protein 5e-45 42

• Homologs from CARD and BacMet (resistance genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein BAC0164 Protein 2e-47 43

• Homologs from VFDB (virulence genes)

GeneGenBank Accn Product ID of source DB Alignment Type E-val Identity
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein VFG1042 Protein 2e-47 43
DIP0585 NP_938961.1 iron ABC transporter ATP-binding protein VFG0925 Protein 2e-47 41