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Name : DIP2314 (DIP2314) Accession : NP_940616.1 Strain : Corynebacterium diphtheriae NCTC13129 Genome accession: NC_002935 Putative virulence/resistance : Unknown Product : type I restriction/modification system DNA methylase Function : - COG functional category : V : Defense mechanisms COG ID : COG0286 EC number : - Position : 2413807 - 2415414 bp Length : 1608 bp Strand : - Note : Similar to Klebsiella pneumoniae HsdM SWALL:O34139 (EMBL:U93843) (539 aa) fasta scores: E(): 6.2e-66, 45.37% id in 551 aa, and to Pasteurella multocida HsdM or PM1537 SWALL:Q9CKR9 (EMBL:AE006190) (568 aa) fasta scores: E(): 2e-51, 44.38% id in 561 aa DNA sequence : ATGGTACGGAAGAAGAAGGAAGTGGCGCAGGTCCCTTCCACCTCTAAGGAAATCAAGGACACATTGTGGAAGTCCGCGGA TAAGCTTCGCGGTTCTATGGATGCGTCGCAGTACAAGGATGTTGCTCTGGGGCTGGTGTTCCTAAAGTATGTATCGGATT CCTTTGAGGAACGTCAGAAGGAAATCCGCGCGGAGCTAGAAGGCAAGGGCTTCGATGAGGAATACATCCTAGAAGATCTT GCCGACGTTGACGCTTACACCAGCGAGAATGTTTTTTGGGTGGCGTCGAATGCCCGTTGGGACTTCCTAAAGAAGTATTC CAAGGGCATGGATCTGGAAGGAAAACACAAGTCTATCGGCAAGTTGATCGATGAGGCTATGCAGCAGCTCATGGCGGATA ACGAATCGCTACTGGGCACGCTGCCGCAGATTTATGGCAAGGACAATATCGACCAGCGCCGTCTCGGTGAATTAGTGGAC CTGTTTAGCTCTACGTATTTTGCCAGCACTAAGGATAAGAAGGCCCGCGACCTGCTTGGGGAGGTTTACGAGTACTTTCT GGATAAGTTCGCCAAGGCCGAGGGTAAGAGGGGTGGCGAGTTTTATACGCCGCAGCCGGTCGTGCGGACGTTGGTAGAAA TCCTTGAGCCGACTGAGGGGCGTGTGTATGACCCATGCTGTGGTTCGGGTGGCATGTTTGTGCAGGCGGAAAAGTTCTTG GAGGTTACCAAGCGTGACCGCAGCAACATTGCGGTTTATGGCCAAGAACTCAATGAGCGTACTTGGCGAATGGCGAAGAT GAACTTGGCTATTCACGCCATCAGTTCGTCCGGTTTGGGTGAGCGTTGGGGTGACACGTTTGCTCGCGATATTCATGCGG GCACCAAGATGGATTACATCATGGCTAATCCGCCGTTCAACATTAAGGATTGGATCCGCAATGAGGAGGATGCCCGTTGG AAGTACGGTGTGCCTCCGGCGAAGAATGCGAACTTTGCGTGGATACAGCACATCATTTCGAAGCTGAAGGATCACGGCGA AGCTGGTGTTGTGATGGCGAATGGCACCATGACGTCGCAAAGCTCTGGTGAGGGCGAGATCCGTAAGAACATGGTGGAAG ATGATGTTGTTTCGTGTGTGATTGCGTTGCCGGCGCAGTTGTTCCGTGGCACGGGCATTCCGGTGTGCGTGTGGTTTTTT GCTAAGGATAAGTCGGCGGGTGTTGGTGGCAGTGTTGATCGCCGTGGTGAGGTGTTGCTTATCGACGCCCGCCAGCTCGG CCACATGATCGACCGCACGGAGCGGGCGTTTAGTGATGAGGACATCACCAAGATTGCTAATGCGTTCCGAACCTGGCGTG GGCGTAAGTCCGCGGAGGGAGAGTACGAGGACGAGGCGGGATTCTGTAAGTCCGCCACAATTGAGGAGATCCGCGAAGCT GGCTACGCGCTAACACCTGGCCGCTATGTGGGCATGCCTGAGGCCGAAGAAGATGATGAGCCTATCGACGAAAAGATTGC ACGTCTAACCGCAGAACTGACTGCTGCATTGGACGAGTCTGCACGTTTGGACGCTGTCGTCCGCGAACAGCTGGGGAGGT TGAAGTGA Protein sequence : MVRKKKEVAQVPSTSKEIKDTLWKSADKLRGSMDASQYKDVALGLVFLKYVSDSFEERQKEIRAELEGKGFDEEYILEDL ADVDAYTSENVFWVASNARWDFLKKYSKGMDLEGKHKSIGKLIDEAMQQLMADNESLLGTLPQIYGKDNIDQRRLGELVD LFSSTYFASTKDKKARDLLGEVYEYFLDKFAKAEGKRGGEFYTPQPVVRTLVEILEPTEGRVYDPCCGSGGMFVQAEKFL EVTKRDRSNIAVYGQELNERTWRMAKMNLAIHAISSSGLGERWGDTFARDIHAGTKMDYIMANPPFNIKDWIRNEEDARW KYGVPPAKNANFAWIQHIISKLKDHGEAGVVMANGTMTSQSSGEGEIRKNMVEDDVVSCVIALPAQLFRGTGIPVCVWFF AKDKSAGVGGSVDRRGEVLLIDARQLGHMIDRTERAFSDEDITKIANAFRTWRGRKSAEGEYEDEAGFCKSATIEEIREA GYALTPGRYVGMPEAEEDDEPIDEKIARLTAELTAALDESARLDAVVREQLGRLK |
| Gene | GenBank Accn | Product | Virulance or Resistance | PAI or REI | Alignment Type | E-val | Identity |
| hsdM | YP_251979.1 | type I restriction-modification system DNA methylase | Not tested | SCCmec | Protein | 4e-127 | 50 |
| hsdM | BAH57701.1 | type I restriction-modification system DNA methylase | Not tested | Type-VII SCCmec | Protein | 7e-127 | 50 |
| hsdM | BAD24842.1 | HsdM protein | Not tested | Type-V SCCmec | Protein | 4e-127 | 49 |
| api49 | CAF28523.1 | putative HsdM-like N-methyl transferase | Not tested | YAPI | Protein | 2e-110 | 45 |
